2',6'-dimethyltyrosine has been researched along with endomorphin 2 in 4 studies
| Studies (2',6'-dimethyltyrosine) | Trials (2',6'-dimethyltyrosine) | Recent Studies (post-2010) (2',6'-dimethyltyrosine) | Studies (endomorphin 2) | Trials (endomorphin 2) | Recent Studies (post-2010) (endomorphin 2) |
|---|---|---|---|---|---|
| 27 | 0 | 6 | 443 | 0 | 112 |
| Protein | Taxonomy | 2',6'-dimethyltyrosine (IC50) | endomorphin 2 (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.0482 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.001 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0241 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Imam, MZ; Kong, D; Kuo, A; Smith, MT; Williams, CM | 1 |
| Bryant, SD; Jinsmaa, Y; Lazarus, LH; Li, T; Marczak, ED; Okada, Y; Tsuda, Y | 1 |
| do-Rego, JC; Fichna, J; Gach, K; Janecka, A; Janecki, T; Kluczyk, A; Perlikowska, R; Piekielna, J; Toth, G; Wyrębska, A | 1 |
| Benedek, G; Horváth, G; Kovács, G; Mallareddy, JR; Petrovszki, Z; Tóth, G | 1 |
4 other study(ies) available for 2',6'-dimethyltyrosine and endomorphin 2
| Article | Year |
|---|---|
Analgesic Opioid Ligand Discovery Based on Nonmorphinan Scaffolds Derived from Natural Sources.
Topics: Analgesics, Opioid; Animals; Biological Products; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Discovery; Humans; Ligands; Pain; Peptides; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2022 |
[N-allyl-Dmt1]-endomorphins are micro-opioid receptor antagonists lacking inverse agonist properties.
Topics: Analgesics, Opioid; Animals; Brain; Cell Line; Cell Membrane; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Male; Mice; Oligopeptides; Protein Binding; Radioligand Assay; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Tyrosine | 2007 |
Effect of 2',6'-dimethyl-L-tyrosine (Dmt) on pharmacological activity of cyclic endomorphin-2 and morphiceptin analogs.
Topics: Amino Acid Sequence; Animals; Drug Interactions; Endorphins; Male; Mice; Oligopeptides; Opioid Peptides; Peptides, Cyclic; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship; Tyrosine | 2011 |
Characterization of antinociceptive potency of endomorphin-2 derivatives with unnatural amino acids in rats.
Topics: Aminobutyrates; Analgesics, Opioid; Animals; Arthralgia; Carboxylic Acids; Chronic Pain; Cyclobutanes; Disease Models, Animal; Drug Design; Edema; Hyperalgesia; Injections, Spinal; Male; Nociceptors; Oligopeptides; p-Fluorophenylalanine; Rats; Rats, Wistar; Tyrosine | 2012 |