2'-5'-oligoadenylate trimer has been researched along with oligonucleotides in 127 studies
Studies (2'-5'-oligoadenylate trimer) | Trials (2'-5'-oligoadenylate trimer) | Recent Studies (post-2010) (2'-5'-oligoadenylate trimer) | Studies (oligonucleotides) | Trials (oligonucleotides) | Recent Studies (post-2010) (oligonucleotides) |
---|---|---|---|---|---|
590 | 4 | 88 | 23,128 | 245 | 7,331 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 114 (89.76) | 18.7374 |
1990's | 9 (7.09) | 18.2507 |
2000's | 3 (2.36) | 29.6817 |
2010's | 1 (0.79) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Birdsall, NJ; Brown, RE; Gilbert, CS; Hovanessian, AG; Kerr, IM; Martin, EM; Williams, BR | 1 |
Brown, RE; Gilbert, CS; Golgher, RR; Kerr, IM; Williams, BR | 1 |
Gerdes, PA; Kidder, GM | 1 |
Alster, DK; Kinjo, JE; Lesiak, K; Pabuccuoglu, A; Torrence, PF | 1 |
Castora, FJ; Erickson, CE; Kovács, T; Lesiak, K; Torrence, PF | 1 |
Hirano, A; Mori, H; Sawai, H | 1 |
Itkes, AV; Severin, ES; Tunitskaia, VL | 1 |
Kerr, IM; Reese, CB; Serafinowska, HT; Watling, D | 1 |
Eslami, B; Konno, S; Wu, JM | 1 |
Imai, J; Lesiak, K; Torrence, PF | 2 |
Itkes, AV; Kafiani, CA; Kartasheva, ON; Severin, ES; Tunitskaya, VL; Turpaev, KT | 1 |
Bayard, B; Bisbal, C; Lebleu, B; Leserman, LD | 1 |
Jamoulle, JC; Lesiak, K; Torrence, PF | 1 |
Lesiak, K; Torrence, PF | 1 |
Hubbell, HR; Lee, C; Pequignot, EC; Suhadolnik, RJ; Willis, DH | 1 |
Rhodes, CJ; Taylor, KW | 1 |
Silverman, RH | 1 |
Lee, C; Suhadolnik, RJ | 1 |
Devash, Y; Reichenbach, NL; Reichman, M; Sela, I; Suhadolnik, RJ | 1 |
Bayard, B; Bisbal, C; Cnockaert, J; Huez, G; Lebleu, B; Silhol, M | 1 |
Cayley, PJ; Davies, JA; Kerr, IM; McCullagh, KG | 1 |
Gosselin, G; Imbach, JL; Müller, WE; Schröder, HC | 1 |
Brown, RE; Cayley, PJ; Gilbert, CS; Kerr, IM; Knight, M; Silverman, RH; Wreschner, DH | 1 |
Ferbus, D; Justesen, J; Thang, MN | 1 |
Kerr, IM; McCauley, JW; Skehel, JJ; Wreschner, DH | 1 |
de Haseth, PL; Uhlenbeck, OC | 1 |
Alonso, A; Krieg, L; Winter, H | 1 |
Kimchi, A; Revel, M; Shure, H | 1 |
James, TC; Kerr, IM; Silverman, RH; Wreschner, DH | 1 |
Floyd-Smith, G; Lengyel, P; Slattery, E | 1 |
Goswami, BB; Sharma, OK | 1 |
Baglioni, C; Maroney, PA; Nilsen, TW | 2 |
Cayley, PJ; Kerr, IM; Knight, M; Silverman, RH; Wreschner, DH | 1 |
Adamus, WS | 1 |
Czarniecki, CW; Falk, H; Friedman, RM; Panet, A | 1 |
Kimchi, A; Lapidot, Y; Panet, A; Rapoport, S; Revel, M; Shure, H | 1 |
Duncan, R; Humphreys, T | 1 |
Charubala, R; Dang, AQ; Doetsch, PW; Flick, MB; Henderson, EE; Mosca, JD; Pfleiderer, W; Reichenbach, NL; Sawada, Y; Suhadolnik, RJ; Wu, JM | 1 |
Baglioni, C; Nilsen, TW; Wood, DL | 2 |
Brown, RE; Hovanessian, AG; Kerr, IM; Knight, M; Martin, EM; Roberts, WK | 1 |
Brown, RE; Gilbert, CS; Golgher, RR; Kerr, IM; Roberts, WK; Silverman, RH; Williams, BR; Wreschner, DH | 1 |
Brown, RE; Cayley, PJ; Kerr, IM | 1 |
Hovanessian, AG; Martin, EM; Reisinger, DM; Williams, BR | 1 |
Biggs, S; Devash, Y; Sela, I | 1 |
Floyd-Smith, G; Lengyel, P; Yoshie, O | 1 |
Baglioni, C; Maroney, PA; Nilsen, TW; Robertson, HD | 1 |
Higashi, Y; Sokawa, Y | 1 |
Leanderson, T; Lundgren, E; Nordfelth, R | 1 |
Fridey, SM; Malik, M; Parthasarathy, R | 1 |
Chapekar, MS; Glazer, RI | 2 |
James, TC; Kerr, IM; Silverman, RH; Skehel, JJ; Wreschner, DH | 1 |
Hughes, BG; Muse, DD; Robins, RK; Srivastava, PC | 1 |
Bosch, JV; Bugany, H; Ferdinand, FJ; Friis, RR | 1 |
Balzarini, J; De Clercq, E; Imai, J; Lesiak, K; Torrence, PF; Warrinnier, J | 1 |
Floyd-Smith, G; Lengyel, P; Samanta, H; Sehgal, PB; St Laurent, G; Yoshie, O | 1 |
Farina, B; Leone, E; Pivazian, AD; Suzuki, H; Vartanian, AA; Zhelkovsky, AM | 1 |
Baglioni, C; Crea, R; D'Alessandro, SB; den Hartog, JA; Nilsen, TW; van Boom, JH | 1 |
Ganz, PR; Kiss, GB; Pearlman, RE | 1 |
Kerr, IM; Knight, M; Silverman, RH; Wreschner, DH | 1 |
Sokawa, Y | 1 |
Charubala, R; Doetsch, PW; Henderson, EE; Pfleiderer, W; Suhadolnik, RJ | 1 |
Content, J; Dumont, JE; Etienne-Smekens, M; Vandenbussche, P | 1 |
Dawid, IB; Di Nocera, PP | 1 |
Itkes, AV; Kochetkova, MN; Severin, ES; Tunitskaia, VL | 1 |
Brown, RE; Hersh, CL; Kerr, IM; Roberts, WK; Stark, GR; Swyryd, EA | 1 |
Itkes, AV; Kafiani, CA; Kartasheva, ON; Severin, ES; Turpaev, KT | 1 |
Esteban, M; Paez, E | 1 |
Black, PL; Charubala, R; Henderson, EE; Pfleiderer, W; Suhadolnik, RJ | 1 |
Imai, J; Torrence, PF | 2 |
Jurovcík, M; Smrt, J; Vilcek, S; Vrtiak, OJ | 1 |
Kerr, IM; Rice, AP; Roberts, WK | 1 |
Hersh, CL; Kerr, IM; Reid, TR; Stark, GR | 1 |
Cailla, H; Laurence, L; Marti, J; Roux, D | 1 |
Imai, J; Jamoulle, JC; Lesiak, K; Torrence, PF | 1 |
Ishibashi, K; Itoh, M; Sawai, H; Watanabe, S | 1 |
Floyd-Smith, G; Imai, J; Lesiak, K; Torrence, PF | 1 |
Eslami, B; Semproni, AR; Wu, JM | 1 |
Sawai, H | 3 |
Hirao, I; Ishido, Y; Miura, K | 1 |
Baydoun, H; Müller, WE; Schenk, P; Schröder, HC; Wagner, KG | 1 |
Friedman, R; Hersh, CL; Reid, TR; Stark, GR | 1 |
Dornfest, BS; Kobylack, M; Orlic, D | 1 |
Mundry, KW; Schön, A | 1 |
Kostka, G; Schweiger, A | 1 |
Imai, J; Jamoulle, JC; Lesiak, K; Sawai, H; Torrence, PF | 1 |
Arad, G; Lapidot, Y; Panet, A; Rappoport, S | 1 |
Alma, NC; Harmsen, BJ; Hilbers, CW; van Boom, JH; van der Marel, G | 1 |
Hughes, BG; Robins, RK | 1 |
Imai, J; Johnston, MI; Torrence, PF | 2 |
Karemfillis, T; Koliais, SI; Kortsaris, A; Taylor-Papadimitriou, J | 1 |
Dieffenbach, CW; Drocourt, JL; Justesen, J; Thang, MN; Ts'o, PO | 1 |
Crea, R; Goswami, BB; Sharma, OK; Van Boom, JH | 1 |
Lohrmann, R | 1 |
Barnett, JW; Eppstein, DA; Larsen, MA; March, YV; Prisbe, EJ; Schryver, BB; Verheyden, JP | 1 |
Konski, AA; Orlic, D; Quaini, F; Wu, JM | 1 |
Baglioni, C; McCandless, S; Nilsen, TW | 1 |
Gdovinová, A; Sangret, M; Vilcek, S; Vrtiak, OJ | 1 |
Sawai, H; Shinomiya, T | 2 |
Imai, J; Johnston, MI; Lesiak, K; Torrence, PF | 1 |
Crea, R; den Hartog, JA; van Boom, JH; Wijnands, RA | 1 |
Baglioni, C; Minks, MA | 1 |
Borissov, RG; Chernolovskaya, EL; Gorn, VV; Kobets, ND; Vlassov, VV | 1 |
Cruz, BM; Fingerote, RJ; Fung, LS; Gorczynski, RM; Hubbell, HR; Levy, GA; Suhadolnik, RJ | 1 |
Kuroda, K; Ozaki, H; Sawai, H; Seki, J | 1 |
Hemminga, MA; van der Graaf, M; Wolfs, CJ | 1 |
Cirino, NM; Li, G; Silverman, RH; Torrence, PF; Xiao, W | 1 |
Buff, R; Hunziker, J | 1 |
Kawai, G; Okutsu, T; Sawai, H; Shimazu, M; Shiozuka, K | 1 |
BARANOWSKA, J; SHUGAR, D | 1 |
BERTRAND, G | 1 |
DESCHREIDER, AR | 1 |
BROWN, DH; ILLINGWORTH, B | 1 |
MICHELSON, AM | 1 |
DEAN GUELBENZU, M; LOPEZ DE AZCONA, JM; SANTOS RUIZ, A | 1 |
Kitade, Y; Mizutani, Y; Mochizuki, M; Nakamura, KT; Nakanishi, M; Tanaka, N; Ueno, Y | 1 |
Banerjee, AK; Das Gupta, J; Dong, B; Gudkov, A; Jha, BK; Mao, H; Nakamura, AO; Sawai, H; Silverman, KM; Silverman, RH; Thakur, CS | 1 |
Gening, ML; Gerbst, AG; Nifantiev, NE; Roy, A; Saha, T; Talukdar, P; Titov, DV; Tsvetkov, YE | 1 |
3 review(s) available for 2'-5'-oligoadenylate trimer and oligonucleotides
Article | Year |
---|---|
[Mechanisms of the regulation of the biological activity of the cell by 2',5-oligoadenylate].
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Animals; Cell Division; Cell Line; Cells, Cultured; Cyclic AMP; Exoribonucleases; Humans; Interferons; Kinetics; Models, Biological; Oligonucleotides; Oligoribonucleotides; Ribonuclease, Pancreatic; Substrate Specificity | 1985 |
[(2'-5') oligoadenylate and its synthetase (author's transl)].
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Animals; Mice; Nucleotidyltransferases; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; Virus Replication | 1981 |
[Oligonucleotide structural features involved in binding to and activation of the 2-5 A-dependent endoribonuclease].
Topics: Adenine Nucleotides; Animals; Endoribonucleases; Mice; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; RNA, Double-Stranded; Structure-Activity Relationship | 1983 |
124 other study(ies) available for 2'-5'-oligoadenylate trimer and oligonucleotides
Article | Year |
---|---|
Cell-free protein synthesis and interferon action: protein kinase(s) and an oligonucleotide effector, pppA2'p5'A2'p5'A.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Adenosine Triphosphate; Animals; Cell-Free System; Interferons; L Cells; Mice; Oligonucleotides; Oligoribonucleotides; Peptide Chain Initiation, Translational; Peptide Initiation Factors; Phosphorylation; Polynucleotide Ligases; Protein Kinases; RNA, Double-Stranded | 1979 |
Natural occurrence of 2-5A in interferon-treated EMC virus-infected L cells.
Topics: Adenine Nucleotides; Animals; Cell-Free System; Encephalomyocarditis virus; Interferons; L Cells; Mice; Oligonucleotides; Oligoribonucleotides; RNA, Double-Stranded; RNA, Messenger; Virus Replication | 1979 |
Metabolism of oligo(A) tracts and association of oligo(A)(+)RNA with polysomes in molluscan embryos.
Topics: Adenine Nucleotides; Animals; Embryo, Nonmammalian; Mollusca; Oligonucleotides; Oligoribonucleotides; Polyribosomes; Subcellular Fractions | 1979 |
Synthesis and biological activity of uronic acid analogues of 2-5A[5'-O-triphosphoryladenylyl(2----5')adenylyl-(2'----5')adenosine].
Topics: Adenine Nucleotides; Animals; Cell Line; Endoribonucleases; Humans; Liver; Lymphoid Tissue; Mice; Oligonucleotides; Oligoribonucleotides; Protein Synthesis Inhibitors; Uronic Acids | 1992 |
2',5'-oligoadenylates inhibit relaxation of supercoiled DNA by calf thymus DNA topoisomerase I.
Topics: Adenine Nucleotides; Animals; Antiviral Agents; Cattle; DNA, Superhelical; Electrophoresis, Agar Gel; Gene Expression Regulation; Kinetics; Oligonucleotides; Oligoribonucleotides; Phosphorylation; Thymus Gland; Topoisomerase I Inhibitors | 1991 |
Uranyl ion-catalyzed synthesis of several 8-substituted 2'-5'-oligoadenylates, and their properties.
Topics: Adenine Nucleotides; Adenosine; Oligonucleotides; Oligoribonucleotides; Polymers; Uranium | 1990 |
Analogue inhibitor of 2-5A action: effect on the interferon-mediated inhibition of encephalomyocarditis virus replication.
Topics: Adenine Nucleotides; Animals; Cell-Free System; Encephalomyocarditis virus; Enzyme Activation; Interferons; L Cells; Mice; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; Ribonucleases; RNA, Ribosomal; Thionucleotides; Virus Replication | 1985 |
Effects of K+ concentration on inhibition of protein synthesis by trimer and tetramer triphosphates of 2',5'-oligoadenylates in rabbit reticulocyte lysates.
Topics: Adenine Nucleotides; Animals; Cell Line; Endoribonucleases; Humans; Leukemia, Myeloid, Acute; Oligonucleotides; Oligoribonucleotides; Poly A; Potassium; Protein Biosynthesis; Rabbits; Reticulocytes; RNA; RNA, Messenger | 1985 |
Respective role of each of the purine N-6 amino groups of 5'-O-triphosphoryladenylyl(2'----5')adenylyl(2----5')adenosine in binding to and activation of RNase L.
Topics: Adenine Nucleotides; Animals; Cell Line; Encephalomyocarditis virus; Endoribonucleases; Enzyme Activation; Humans; Inosine; Mice; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; RNA, Ribosomal; RNA, Viral; Structure-Activity Relationship | 1985 |
Activities of cAMP-dependent protein kinase and enzymes of 2',5'-oligoadenylate metabolism in NIH 3T3 cells deepening into the resting state.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Animals; Cell Line; Cyclic AMP; Exoribonucleases; Interphase; Mice; Oligonucleotides; Oligoribonucleotides; Protein Kinase Inhibitors; Protein Kinases | 1985 |
Antiviral activity in L1210 cells of liposome-encapsulated (2'-5')oligo(adenylate) analogues.
Topics: Adenine Nucleotides; Animals; Antibodies, Monoclonal; Antiviral Agents; Cell-Free System; Endoribonucleases; Enzyme Activation; Leukemia L1210; Liposomes; Methionine; Mice; Neoplasm Proteins; Oligonucleotides; Oligoribonucleotides; Staphylococcal Protein A; Vesicular stomatitis Indiana virus | 1985 |
Respective role of each of the purine N7 nitrogens of 5'-O-triphosphoadenylyl(2'----5')adenylyl(2'----5')adenosine in binding to and activation of the RNase L of mouse cells.
Topics: Adenine Nucleotides; Alkaline Phosphatase; Animals; Endoribonucleases; Enzyme Activation; Indicators and Reagents; Kinetics; L Cells; Mice; Oligonucleotides; Oligoribonucleotides; Phosphodiesterase I; Phosphoric Diester Hydrolases; Protein Binding; Substrate Specificity; Tubercidin | 1987 |
Phosphorylation of 2-5A core 5'-diphosphate to 2-5A in mouse L cell extracts.
Topics: Adenine Nucleotides; Animals; Biotransformation; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; L Cells; Mice; Oligonucleotides; Oligoribonucleotides; Phosphorylation; Poly A | 1985 |
Differential antiproliferative actions of 2',5' oligo A trimer core and its cordycepin analogue on human tumor cells.
Topics: Adenine Nucleotides; Adenosine; Cell Division; Cell Line; Coformycin; Culture Techniques; Dose-Response Relationship, Drug; Drug Resistance; Humans; Neoplasms; Oligodeoxyribonucleotides; Oligonucleotides; Oligoribonucleotides; Pentostatin | 1985 |
2-5A-dependent endoribonuclease activity and effects of A2'p5'A2'p5'A (2-5A core) in mouse pancreatic islets.
Topics: Adenine Nucleotides; Animals; Endoribonucleases; Glucose; Islets of Langerhans; Male; Mice; Mice, Inbred DBA; Oligonucleotides; Oligoribonucleotides; Poly I-C; Proinsulin | 1985 |
Functional analysis of 2-5A-dependent RNase and 2-5a using 2',5'-oligoadenylate-cellulose.
Topics: Adenine Nucleotides; Animals; Cellulose; Chemical Phenomena; Chemistry; Endoribonucleases; L Cells; Mice; Oligonucleotides; Oligoribonucleotides; Phosphorus Radioisotopes; Radioligand Assay; Reticulocytes | 1985 |
2',5'-Oligoadenylates chiral at phosphorus: enzymatic synthesis, properties, and biological activities of 2',5'-phosphorothioate trimer and tetramer analogues synthesized from (SP)-ATP alpha S.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Animals; Drug Stability; Interferon Type I; Kinetics; L Cells; Mice; Oligonucleotides; Oligoribonucleotides; Phosphorus Radioisotopes; Structure-Activity Relationship; Substrate Specificity; Thionucleotides | 1985 |
Plant oligoadenylates: enzymatic synthesis, isolation, and biological activities.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Animals; Cells, Cultured; Endoribonucleases; Humans; Interferon Type I; Kinetics; Nicotiana; Oligonucleotides; Oligoribonucleotides; Phosphorus Radioisotopes; Plants; Plants, Toxic; Rabbits; Reticulocytes; Tritium | 1985 |
Increased stability and antiviral activity of 2'-O-phosphoglyceryl derivatives of (2'-5')oligo(adenylate).
Topics: Adenine Nucleotides; Antiviral Agents; Chemical Phenomena; Chemistry; Drug Stability; Glyceric Acids; Oligonucleotides; Oligoribonucleotides; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Phosphorylation; Ribose; Vesicular stomatitis Indiana virus | 1984 |
Activation of the ppp(A2'p)nA system in interferon-treated, herpes simplex virus-infected cells and evidence for novel inhibitors of the ppp(A2'p)nA-dependent RNase.
Topics: Adenine Nucleotides; Cell Line; Cell Transformation, Viral; Chromatography, High Pressure Liquid; Electrophoresis, Agar Gel; Endoribonucleases; Enzyme Activation; Interferon Type I; Kinetics; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; Ribonucleases; RNA, Ribosomal; Simplexvirus; Virus Replication | 1984 |
Influence of the xyloadenosine analogue of 2',5'-oligoriboadenylate on poly(A)-specific, 2',5'-oligoriboadenylate degrading 2',3'-exoribonuclease and further enzymes involved in poly(A)(+)mRNA metabolism.
Topics: Adenine Nucleotides; Animals; Cattle; Endoribonucleases; Exoribonucleases; In Vitro Techniques; Oligonucleotides; Oligoribonucleotides; Poly A; Polynucleotide Adenylyltransferase; Ribonucleoproteins; RNA, Messenger | 1984 |
Radioimmune, radiobinding and HPLC analysis of 2-5A and related oligonucleotides from intact cells.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Interferons; Mice; Oligonucleotides; Oligoribonucleotides; Polynucleotide Ligases; Radioimmunoassay; Radioligand Assay | 1980 |
2'5' oligoadenylate synthetase, an interferon induced enzyme: direct assay methods for the products, 2'5' oligoadenylates and 2'5' co-oligonucleotides.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Adenosine Triphosphate; Animals; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Hydrogen-Ion Concentration; Interferons; Oligonucleotides; Oligoribonucleotides; Polynucleotide Ligases; Rabbits; Reticulocytes | 1980 |
Interferon action--sequence specificity of the ppp(A2'p)nA-dependent ribonuclease.
Topics: Adenine Nucleotides; Animals; Base Sequence; Cells, Cultured; Enzyme Activation; Humans; Interferons; Mice; Oligonucleotides; Oligoribonucleotides; Ribonucleases; Substrate Specificity | 1981 |
Interaction of Escherichia coli host factor protein with oligoriboadenylates.
Topics: Adenine Nucleotides; Binding Sites; Binding, Competitive; Carrier Proteins; Chemical Phenomena; Chemistry; Cyclization; Escherichia coli; Escherichia coli Proteins; Filtration; Host Factor 1 Protein; Integration Host Factors; Oligonucleotides; Oligoribonucleotides; Protein Binding; RNA; Spectrometry, Fluorescence | 1980 |
Poly(A)- and oligo(A)-adjacent sequences in RNA from the large hnRNP complexes of rat liver.
Topics: Adenine Nucleotides; Animals; Base Sequence; Cell Nucleus; DNA; Liver; Nucleic Acid Hybridization; Oligonucleotides; Oligoribonucleotides; Poly A; Rats; RNA; RNA, Heterogeneous Nuclear; RNA, Messenger | 1981 |
Anti-mitogenic function of interferon-induced (2'-5')oligo(adenylate) and growth-related variations in enzymes that synthesize and degrade this oligonucleotide.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Animals; Cell Division; Cells, Cultured; Chlorocebus aethiops; Concanavalin A; Fibroblasts; Interferons; Kidney; Lymphocytes; Mice; Oligonucleotides; Oligoribonucleotides; Polynucleotide Ligases; Protein Biosynthesis; RNA; Spleen | 1981 |
Ribosomal RNA cleavage, nuclease activation and 2-5A(ppp(A2'p)nA) in interferon-treated cells.
Topics: Adenine Nucleotides; Animals; Endonucleases; Enzyme Activation; Interferons; Kinetics; L Cells; Mice; Oligonucleotides; Oligoribonucleotides; Reticulocytes; RNA, Ribosomal | 1981 |
Interferon action: RNA cleavage pattern of a (2'-5')oligoadenylate--dependent endonuclease.
Topics: Adenine Nucleotides; Animals; Carcinoma, Ehrlich Tumor; Endoribonucleases; HeLa Cells; Humans; Interferons; Mice; Oligonucleotides; Oligoribonucleotides; Ribonucleases; Ribonucleotides; RNA; Substrate Specificity | 1981 |
Inhibition of vaccinia mRNA methylation by 2',5'-linked oligo(adenylic acid) triphosphate.
Topics: Adenine Nucleotides; Animals; Interferons; L Cells; Methylation; Methyltransferases; Mice; Oligonucleotides; Oligoribonucleotides; RNA Caps; RNA, Messenger; RNA, Viral; Vaccinia virus; Virus Replication | 1981 |
Double-stranded RNA causes synthesis of 2',5'-oligo(A) and degradation of messenger RNA in interferon-treated cells.
Topics: Adenine Nucleotides; Binding, Competitive; Endonucleases; Enzyme Activation; Enzyme Induction; Fibroblasts; HeLa Cells; Humans; Interferons; Kinetics; Oligonucleotides; Oligoribonucleotides; Poly I-C; RNA, Messenger | 1981 |
The 2-5A (pppA2'p5'A2'p5'A) and protein kinase systems in interferon-treated and control cells.
Topics: Adenine Nucleotides; Animals; Chromatography, High Pressure Liquid; Drug Stability; Enzyme Activation; Interferons; Kinetics; Nucleic Acid Conformation; Oligonucleotides; Oligoribonucleotides; Phosphorylation; Protein Biosynthesis; Protein Kinases; Rabbits; Reticulocytes; RNA, Double-Stranded | 1981 |
Oligonucleotides - a better alternative to interferon?
Topics: Adenine Nucleotides; Costs and Cost Analysis; Humans; Interferons; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; Research Design | 1981 |
Effect of 2'5'-oligoadenylic acid on a mouse cell line partially resistant to interferon.
Topics: Adenine Nucleotides; Animals; Cell Line; DNA; Drug Resistance; Interferons; Kinetics; L Cells; Mice; Moloney murine leukemia virus; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; Ribonucleases; Vesicular stomatitis Indiana virus; Viral Proteins; Virus Replication | 1981 |
Antimitogenic effects of interferon and (2'-5')-oligoadenylate in synchronized 3T3 fibroblasts.
Topics: Adenine Nucleotides; Animals; DNA; Endoribonucleases; Enzyme Activation; Fibroblasts; Interferons; Interphase; Kinetics; Macromolecular Substances; Mice; Mice, Inbred BALB C; Mitosis; Oligonucleotides; Oligoribonucleotides; Ribonucleases; Structure-Activity Relationship | 1981 |
Multiple oligo(A) tracts associated with inactive sea urchin maternal mRNA sequences.
Topics: Adenine Nucleotides; Animals; Embryo, Nonmammalian; Female; Fertilization; Kinetics; Oligonucleotides; Oligoribonucleotides; Ovum; Poly A; Polyribosomes; RNA; RNA, Messenger; Sea Urchins | 1981 |
Core (2'-5')oligoadenylate and the cordycepin analog: inhibitors of Epstein--Barr virus-induced transformation of human lymphocytes in the absence of interferon.
Topics: Adenine Nucleotides; Adult; Cell Transformation, Viral; Cells, Cultured; Deoxyadenine Nucleotides; Drug Stability; Female; Fetal Blood; Herpesvirus 4, Human; Humans; Infant, Newborn; Interferons; Kinetics; Lymphocytes; Oligodeoxyribonucleotides; Oligonucleotides; Oligoribonucleotides; Pregnancy | 1981 |
Presence of 2',5'-oligo(A) and of enzymes that synthesize, bind, and degrade 2',5'-oligo(A) in HeLa cell nuclei.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Binding, Competitive; Cell Nucleus; Endoribonucleases; HeLa Cells; Humans; Interferons; Kinetics; Nucleotidyltransferases; Oligonucleotides; Oligoribonucleotides; Ribonucleases | 1982 |
Enzymic synthesis, purification, and fractionation of (2'-5')-oligoadenylic acid.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; HeLa Cells; Humans; Interferons; Kinetics; L Cells; Mice; Nucleotidyltransferases; Oligonucleotides; Oligoribonucleotides; Poly I-C; Rabbits; Reticulocytes; RNA, Double-Stranded | 1981 |
Assay of (2'-5')-oligo(A) synthesized in vitro and the analysis of naturally occurring (2'-5')-oligo(A) from intact cells.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Chromatography, Affinity; HeLa Cells; Humans; Interferons; Kinetics; L Cells; Mice; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; Rabbits; Radioisotope Dilution Technique; Reticulocytes; Tritium | 1981 |
Analysis of (2'-5')-oligo(A) and related oligonucleotides by high-performance liquid chromatography.
Topics: Adenine Nucleotides; Animals; Chromatography, High Pressure Liquid; Interferons; L Cells; Mice; Oligonucleotides; Oligoribonucleotides; Rabbits; Reticulocytes | 1981 |
Procedures for the assay of (2'-5')-oligoadenylic acids and their derivatives in intact cells.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Animals; Cell Division; Cell Line; Cricetinae; Embryo, Mammalian; Humans; Interferons; Kidney; Kinetics; Methods; Nucleotidyltransferases; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; Reticulocytes | 1981 |
Multiplication of tobacco mosaic virus in tobacco leaf disks is inhibited by (2'-5) oligoadenylate.
Topics: Adenine Nucleotides; Animals; Cells, Cultured; Interferons; Kinetics; Nicotiana; Oligonucleotides; Oligoribonucleotides; Plants, Toxic; Tobacco Mosaic Virus; Virus Replication | 1982 |
Interferon action. Covalent linkage of (2'-5')pppApApA(32P)pCp to (2'-5')(A)n-dependent ribonucleases in cell extracts by ultraviolet irradiation.
Topics: Adenine Nucleotides; Animals; Carcinoma, Ehrlich Tumor; Chromatography, DEAE-Cellulose; Chromatography, Gel; Endoribonucleases; HeLa Cells; Humans; Interferons; Mice; Molecular Weight; Oligonucleotides; Oligoribonucleotides; Ribonucleases; Ultraviolet Rays | 1982 |
Synthesis of (2'-5')oligoadenylate and activation of an endoribonuclease in interferon-treated HeLa cells infected with reovirus.
Topics: Adenine Nucleotides; Endoribonucleases; Enzyme Activation; HeLa Cells; Humans; Interferons; Mammalian orthoreovirus 3; Oligonucleotides; Oligoribonucleotides; Polyribosomes; Reoviridae; Ribonucleases; RNA, Messenger; RNA, Ribosomal; RNA, Viral | 1982 |
Heterogeneous nuclear RNA promotes synthesis of (2',5')oligoadenylate and is cleaved by the (2',5')oligoadenylate-activated endoribonuclease.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Adenosine Triphosphate; Deoxyadenine Nucleotides; Endonucleases; Ethidium; HeLa Cells; Humans; Interferons; Nucleotidyltransferases; Oligonucleotides; Oligoribonucleotides; Ribonuclease III; Ribonucleases; RNA, Double-Stranded; RNA, Heterogeneous Nuclear; RNA, Messenger | 1982 |
Microinjection of interferon and 2',5'-oligoadenylate into mouse L cells and their effects on virus growth.
Topics: Adenine Nucleotides; Animals; Interferons; L Cells; Mice; Microinjections; Oligonucleotides; Oligoribonucleotides; Vesicular stomatitis Indiana virus | 1982 |
Antiproliferative effect of (2'-5') oligoadenylate distinct from that of interferon in lymphoid cells.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Animals; Cell Cycle; Cell Division; Concanavalin A; Enzyme Induction; Interferons; Lymphocyte Activation; Lymphocytes; Mice; Oligonucleotides; Oligoribonucleotides; Time Factors | 1982 |
X-ray structure of a dinucleoside monophosphate A2'p5'C that contains a 2'-5' link found in (2'-5')oligo(A)s induced by interferons: single-stranded helical conformation of 2'-5'-linked oligonucleotides.
Topics: Adenine Nucleotides; Interferons; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Oligoribonucleotides; Stereoisomerism; X-Ray Diffraction | 1982 |
Effects of fibroblast and recombinant leukocyte interferons and double-stranded RNA on ppp(2'-5')An synthesis and cell proliferation in human colon carcinoma cells in vitro.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Cell Division; Colonic Neoplasms; DNA Replication; Humans; Interferon Type I; Oligonucleotides; Oligoribonucleotides; Phosphoric Diester Hydrolases; Poly I-C; RNA; RNA, Double-Stranded | 1983 |
rRNA cleavage as an index of ppp(A2'p)nA activity in interferon-treated encephalomyocarditis virus-infected cells.
Topics: Adenine Nucleotides; Animals; Cell-Free System; Encephalomyocarditis virus; Endoribonucleases; Enzyme Activation; HeLa Cells; Interferons; L Cells; Mice; Oligonucleotides; Oligoribonucleotides; Ribosomes; RNA, Ribosomal | 1983 |
2',5'-Oligoadenylates and related 2',5'-oligonucleotide analogues. 1. Substrate specificity of the interferon-induced murine 2',5'-oligoadenylate synthetase and enzymatic synthesis of oligomers.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Animals; Chromatography, High Pressure Liquid; Interferons; Kinetics; Mice; Oligonucleotides; Oligoribonucleotides; Ribonucleotides; Structure-Activity Relationship; Substrate Specificity | 1983 |
Inhibition of Rous sarcoma virus assembly by treatment with 2',5' adenosine nucleotides.
Topics: Adenine Nucleotides; Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Oligonucleotides; Oligoribonucleotides; RNA-Directed DNA Polymerase; RNA, Viral; Structure-Activity Relationship; Viral Proteins; Viral Structural Proteins; Virus Replication | 1983 |
Structure--activity relationships for and potentiation of the antimitogenic activity of 2-5A core derived from 2-5A, a mediator of interferon action.
Topics: Adenine Nucleotides; Animals; Drug Synergism; Fibroblasts; Interferons; Mice; Mice, Inbred BALB C; Mitogens; Oligonucleotides; Oligoribonucleotides; Structure-Activity Relationship | 1983 |
Interferon action: two (2'-5')(A)n synthetases specified by distinct mRNAs in Ehrlich ascites tumor cells treated with interferon.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Animals; Carcinoma, Ehrlich Tumor; Endoribonucleases; Female; Interferons; Mice; Molecular Weight; Oligonucleotides; Oligoribonucleotides; Oocytes; RNA, Messenger; Xenopus laevis | 1983 |
Regulation of poly(ADP-ribose) transferase activity by 2',5'-oligoadenylates.
Topics: Adenine Nucleotides; Animals; Cattle; Cell Nucleus; Cytoplasm; Endoribonucleases; In Vitro Techniques; Interferons; Kinetics; L Cells; Male; Mice; NAD+ Nucleosidase; Oligonucleotides; Oligoribonucleotides; Phosphoric Diester Hydrolases; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Testis | 1984 |
Analogs of (2'-5')oligo(A). Endonuclease activation and inhibition of protein synthesis in intact cells.
Topics: Adenine Nucleotides; Cell Transformation, Viral; Endonucleases; Enzyme Activation; HeLa Cells; Humans; Kinetics; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; RNA, Messenger; Structure-Activity Relationship; Vesicular stomatitis Indiana virus | 1981 |
Oligo(A)-stimulated Tetrahymena rDNA synthesis in vito.
Topics: Adenine Nucleotides; Animals; Deoxyribonuclease HindIII; DNA Restriction Enzymes; DNA-Directed DNA Polymerase; DNA, Recombinant; DNA, Ribosomal; Methyltransferases; Nucleic Acid Hybridization; Oligonucleotides; Oligoribonucleotides; Site-Specific DNA-Methyltransferase (Adenine-Specific); Templates, Genetic; Tetrahymena | 1981 |
Radioimmune and radiobinding assays for A2'p5'A2'p5'A, pppA2'p5'A, and related oligonucleotides.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Animals; Immune Sera; Nucleotidyltransferases; Oligonucleotides; Oligoribonucleotides; Phosphorus Radioisotopes; Radioimmunoassay; Radioligand Assay; RNA Ligase (ATP); T-Phages | 1981 |
Inhibition of Epstein-Barr virus-associated nuclear antigen (EBNA) induction by (2',5')oligoadenylate and the cordycepin analog: mechanism of action for inhibition of EBV-induced transformation.
Topics: Adenine Nucleotides; Antigens, Viral; Cell Transformation, Viral; Deoxyadenosines; DNA Replication; Epstein-Barr Virus Nuclear Antigens; Gene Expression Regulation; Herpesvirus 4, Human; Interferon Type I; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; Transcription, Genetic | 1982 |
(2'-5')Oligoadenylate in rat liver: modulation after partial hepatectomy.
Topics: Adenine Nucleotides; Animals; Chromatography, High Pressure Liquid; Hepatectomy; Kinetics; Liver; Liver Regeneration; Male; Micrococcal Nuclease; Oligonucleotides; Oligoribonucleotides; Phosphodiesterase I; Phosphoric Diester Hydrolases; Rats; Rats, Inbred Strains | 1983 |
Interdigitated arrangement of two oligo(A)-terminated DNA sequences in Drosophila.
Topics: Adenine Nucleotides; Animals; Base Sequence; Cloning, Molecular; DNA; DNA Restriction Enzymes; Drosophila melanogaster; Nucleic Acid Hybridization; Oligonucleotides; Oligoribonucleotides | 1983 |
[The process of cyclic adenosine-3',5'-monophosphate phosphodiesterase activation by 2',5'-oligoadenylate].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenine Nucleotides; Animals; Cells, Cultured; Enzyme Activation; Kinetics; Mice; Oligonucleotides; Oligoribonucleotides; Protein Binding | 1983 |
Simian virus 40-infected, interferon-treated cells contain 2',5'-oligoadenylates which do not activate cleavage of RNA.
Topics: Adenine Nucleotides; Animals; Cell Line; Cell Transformation, Viral; Chlorocebus aethiops; Interferon Type I; Kidney; Kinetics; Oligonucleotides; Oligoribonucleotides; Radioimmunoassay; Radioligand Assay; RNA, Messenger; Simian virus 40 | 1984 |
Cyclic AMP-dependent regulation of activities of synthetase and phosphodiesterase of 2',5'-oligoadenylate in NIH 3T3 cells.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Adenylyl Cyclases; Animals; Cell Line; Cyclic AMP; Dactinomycin; Epinephrine; Exoribonucleases; Mice; Oligonucleotides; Oligoribonucleotides; Phosphoric Diester Hydrolases; Protein Kinases; Theophylline | 1984 |
Nature and mode of action of vaccinia virus products that block activation of the interferon-mediated ppp(A2'p)nA-synthetase.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Enzyme Induction; HeLa Cells; Humans; Interferon Type I; L Cells; Mice; Oligonucleotides; Oligoribonucleotides; Phosphoric Monoester Hydrolases; Phosphorylation; Vaccinia virus; Viral Proteins | 1984 |
2',5'-Oligoadenylate trimer core and the cordycepin analog augment the tumoricidal activity of human natural killer cells.
Topics: Adenine Nucleotides; Adenosine; Adjuvants, Immunologic; Adult; Cell Line; Cytotoxicity, Immunologic; Deoxyadenosines; Humans; Killer Cells, Natural; Kinetics; Leukemia, Myeloid; Macromolecular Substances; Oligodeoxyribonucleotides; Oligonucleotides; Oligoribonucleotides | 1984 |
Stability of (2'-5')oligoriboadenylates in various sera.
Topics: Adenine Nucleotides; Animals; Birds; Cattle; Chickens; Edetic Acid; Geese; Kinetics; Oligonucleotides; Oligoribonucleotides; Sheep; Species Specificity; Structure-Activity Relationship; Turkeys | 1984 |
2-5A accumulates to high levels in interferon-treated, vaccinia virus-infected cells in the absence of any inhibition of virus replication.
Topics: Adenine Nucleotides; Animals; Cell Line; Cycloheximide; Cytarabine; Endoribonucleases; Haplorhini; HeLa Cells; Humans; Interferon Type I; Mice; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; RNA, Double-Stranded; RNA, Ribosomal; RNA, Viral; Transcription, Genetic; Vaccinia virus; Viral Proteins; Virus Replication | 1984 |
Analysis of 2',5'-oligoadenylates in cells and tissues.
Topics: Adenine Nucleotides; Animals; Body Fluids; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Female; Haplorhini; Humans; Oligonucleotides; Oligoribonucleotides; Radioimmunoassay; Rats | 1984 |
Effects of human immune interferon on cell viability, (2',5')oligoadenylate synthesis, and polyamine-dependent protein phosphorylation in human colon carcinoma cells in vitro.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Cell Line; Cell Survival; Colonic Neoplasms; DNA Replication; Humans; Interferon-gamma; Kinetics; Neoplasm Proteins; Oligonucleotides; Oligoribonucleotides; Phosphorylation; Polyamines; Protein Biosynthesis; Transcription, Genetic | 1984 |
Immunological evidence for the in vivo occurrence of (2'-5')adenylyladenosine oligonucleotides in eukaryotes and prokaryotes.
Topics: Adenine Nucleotides; Animals; Antibodies, Monoclonal; Antigen-Antibody Complex; Cell Line; Chromatography, High Pressure Liquid; Cross Reactions; Drosophila melanogaster; Escherichia coli; Fungi; Humans; Mice; Mice, Inbred C3H; Oligonucleotides; Oligoribonucleotides; Radioimmunoassay; Rats; Rats, Inbred Strains; Species Specificity; Tissue Distribution | 1984 |
Synthesis and biological activity of tubercidin analogues of ppp5'A2'p(5'A2'p)n5'A.
Topics: Adenine Nucleotides; Animals; Burkitt Lymphoma; Cell Line; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Humans; Indicators and Reagents; L Cells; Magnetic Resonance Spectroscopy; Mice; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; Rabbits; Reticulocytes; Ribonucleosides; Structure-Activity Relationship; Tubercidin | 1984 |
2',5'-Oligoadenylate and 2',5'-oligoadenylate phosphodiesterase in human plasma.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Humans; Microchemistry; Oligonucleotides; Oligoribonucleotides; Radioimmunoassay; Reference Values | 1984 |
Chemical synthesis and biological activities of partially inosine-substituted 2',5'-oligoadenylates: functional discrimination of three adenine amino groups on 2-5A for the binding to and activation of 2-5A-dependent endonuclease.
Topics: Adenine Nucleotides; Animals; Cell Line; Endoribonucleases; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Inosine; L Cells; Mice; Oligonucleotides; Oligoribonucleotides; Structure-Activity Relationship | 1984 |
Biological activities of phosphodiester linkage isomers of 2-5A.
Topics: Adenine Nucleotides; Chemical Phenomena; Chemistry; Endoribonucleases; Kinetics; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; Structure-Activity Relationship | 1983 |
Effect of temperature on ppp(A2'p)nA binding protein activities in rabbit reticulocyte lysates and other mammalian extracts.
Topics: Adenine Nucleotides; Animals; Cells, Cultured; Endoribonucleases; Female; Humans; Kidney; Kinetics; Liver; Lung; Mice; Myocardium; Oligonucleotides; Oligoribonucleotides; Organ Specificity; Placenta; Pregnancy; Reticulocytes; Ribonucleases; Species Specificity; Temperature | 1983 |
NMR, CD and UV studies of 2'-5' and 3'-5' linked oligoadenylates.
Topics: Adenine Nucleotides; Circular Dichroism; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Oligoribonucleotides; Poly A; Spectrophotometry, Ultraviolet | 1983 |
Difference of the 2',5'-oligoadenylate and the 3',5'-oligoadenylate in the formation of base pairings.
Topics: Adenine Nucleotides; Circular Dichroism; Hydrogen Bonding; Nucleic Acid Conformation; Oligonucleotides; Oligoribonucleotides; Poly A; Poly U | 1983 |
Occurrence of short-sized oligo(A) fragments during course of cell cycle and ageing.
Topics: Adenine Nucleotides; Aging; Animals; Cell Cycle; Cells, Cultured; Female; Interphase; Leukemia L5178; Mice; Molecular Weight; Oligonucleotides; Oligoribonucleotides; Oviducts; Phosphorylation; Poly A; Quail; RNA, Messenger | 1983 |
Preparation, characterization, and use of an antiserum specific for 2',5'-oligoadenylates.
Topics: Adenine Nucleotides; Cross Reactions; Hemocyanins; Immune Sera; Oligonucleotides; Oligoribonucleotides; Oxidation-Reduction; Radioimmunoassay; Radioligand Assay; Serum Albumin, Bovine | 1984 |
Inhibition of CFU-E in rat bone marrow perfused with 2'-5'-oligoadenylate core.
Topics: Adenine Nucleotides; Animals; Bone Marrow; Bone Marrow Cells; Erythroblasts; Erythropoietin; Macromolecular Substances; Male; Microscopy, Electron; Oligonucleotides; Oligoribonucleotides; Perfusion; Rats; Stem Cells; Time Factors | 1984 |
Coordinated two-disk nucleation, growth and properties, of virus-like particles assembled from tobacco-mosaic-virus capsid protein with poly(A) or oligo(A) of different length.
Topics: Adenine Nucleotides; Capsid; Chemical Phenomena; Chemistry; Micrococcal Nuclease; Nephelometry and Turbidimetry; Oligonucleotides; Oligoribonucleotides; Poly A; Protein Conformation; RNA, Viral; Spectrophotometry, Ultraviolet; Tobacco Mosaic Virus; Ultracentrifugation | 1984 |
Synthesis of 2',5'-oligoadenylate by rat liver nuclear matrix protein.
Topics: Adenine Nucleotides; Animals; Cell Nucleus; Electrophoresis, Polyacrylamide Gel; In Vitro Techniques; Liver; Oligonucleotides; Oligoribonucleotides; Rats | 1984 |
Oligonucleotide structural parameters that influence binding of 5'-O-triphosphoadenylyl-(2'----5')-adenylyl-(2'----5')-adenosine to the 5'-O-triphosphoadenylyl-(2'----5')-adenylyl-(2'----5')-adenosine dependent endoribonuclease: chain length, phosphorylat
Topics: Adenine Nucleotides; Animals; Endoribonucleases; Mice; Oligonucleotides; Oligoribonucleotides; Phosphorylation; Structure-Activity Relationship | 1984 |
Activation of ribonuclease F by the two isomers (2'--5') oligoadenylate and (3'--5') oligoadenylate.
Topics: Adenine Nucleotides; Alkaline Phosphatase; Endoribonucleases; Enzyme Activation; Escherichia coli; Kinetics; Oligonucleotides; Oligoribonucleotides | 1982 |
500 MHz 1H NMR study of the role of lysines and arginines in the binding of gene-5 protein to oligoadenylic acids.
Topics: Adenine Nucleotides; Arginine; Binding Sites; Coliphages; Lysine; Magnetic Resonance Spectroscopy; Oligonucleotides; Oligoribonucleotides; Protein Binding; Viral Proteins | 1981 |
2',5'-Oligoadenylates and related 2',5'-oligonucleotide analogues. 2. Effect on cellular proliferation, protein synthesis, and endoribonuclease activity.
Topics: Adenine Nucleotides; Animals; Biological Transport; Cell Division; Endoribonucleases; HeLa Cells; Humans; Kinetics; L Cells; Mice; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; Structure-Activity Relationship | 1983 |
5'-O-Monophosphoryladenylyl(2' goes to 5')adenylyl(2' goes to 5')adenosine is an antagonist of the action of 5'-O-triphosphoryladenylyl-(2' goes to 5')adenylyl(2' goes to 5')adenosine and double-stranded RNA.
Topics: Adenine Nucleotides; Animals; Dose-Response Relationship, Drug; Kinetics; L Cells; Mice; Oligonucleotides; Oligoribonucleotides; Poly I-C; Protein Biosynthesis; RNA, Double-Stranded | 1981 |
Mitochondrial protein synthesis is inhibited by 2'-5' linked oligoadenylic acid triphosphate.
Topics: Adenine Nucleotides; Burkitt Lymphoma; Cell Line; Chloramphenicol; Cycloheximide; Humans; Kinetics; Mitochondria; Neoplasm Proteins; Oligonucleotides; Oligoribonucleotides; Poly U; Protein Biosynthesis; T-Lymphocytes | 1980 |
Structural requirements of (2'-5') oligoadenylate for protein synthesis inhibition in human fibroblasts.
Topics: Adenine Nucleotides; Cell Line; Fibroblasts; Humans; Kinetics; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; Proteins; Structure-Activity Relationship | 1982 |
2'-5'-Linked oligo(adenylic acid) and its analogs. A new class of inhibitors of mRNA methylation.
Topics: Adenine Nucleotides; Animals; Kinetics; L Cells; Methyltransferases; Mice; Oligonucleotides; Oligoribonucleotides; RNA, Messenger; Structure-Activity Relationship; Vaccinia virus | 1982 |
Oligonucleotide formation catalyzed by mononucleotide matrices.
Topics: Adenine Nucleotides; Chemical Phenomena; Chemistry; Chromatography, Paper; Lead; Nucleotides; Oligonucleotides; Oligoribonucleotides | 1982 |
Chemical modification potentiates the biological activities of 2-5A and its congeners.
Topics: Adenine Nucleotides; Animals; Drug Stability; Endoribonucleases; L Cells; Mice; Oligonucleotides; Oligoribonucleotides; Structure-Activity Relationship | 1982 |
Analogs of (A2'p)nA. Correlation of structure of analogs of ppp(A2'p)2A and (A2'p)2A with stability and biological activity.
Topics: Adenine Nucleotides; Animals; Biological Assay; Cells, Cultured; DNA Replication; Drug Stability; L Cells; Mice; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; Structure-Activity Relationship | 1982 |
2'5'-adenylate inhibition of erythropoietin-dependent colony formation.
Topics: Adenine Nucleotides; Animals; Colony-Forming Units Assay; Erythropoiesis; Erythropoietin; Hematopoietic Stem Cells; In Vitro Techniques; Male; Oligonucleotides; Oligoribonucleotides; Rats | 1982 |
2', 5'-oligo(A)-activated endonuclease in NIH 3T3 mouse cells chronically infected with Moloney murine leukemia virus.
Topics: Adenine Nucleotides; Animals; Cell Extracts; Cell Line; Cell Nucleus; Cytoplasm; Endoribonucleases; HeLa Cells; Humans; Mice; Moloney murine leukemia virus; Oligonucleotides; Oligoribonucleotides; Phenylmethylsulfonyl Fluoride | 1982 |
[Substance 2-5A--a newly discovered inhibitor of proteosynthesis].
Topics: Adenine Nucleotides; Chemical Phenomena; Chemistry; Oligonucleotides; Oligoribonucleotides; Viral Proteins | 1982 |
Characterization of antibody to 2'-5' linked oligoadenylic acid.
Topics: Adenine Nucleotides; Animals; Antibodies; Antibody Specificity; Cattle; Chromatography, Affinity; Cross Reactions; Immunochemistry; Immunoglobulin G; Oligonucleotides; Oligoribonucleotides; Protein Conformation | 1982 |
Preparation and binding specificity of antibody to 2'-5' linked triadenylic acid.
Topics: Adenine Nucleotides; Antibodies; Antigen-Antibody Complex; Chromatography, Affinity; Cross Reactions; Oligonucleotides; Oligoribonucleotides; Structure-Activity Relationship | 1982 |
Oligonucleotide structural features involved in binding to and activation of the 2-5A-dependent endoribonuclease of L cells.
Topics: Adenine Nucleotides; Animals; Endoribonucleases; Enzyme Activation; Kinetics; L Cells; Mice; Oligonucleotides; Oligoribonucleotides; Structure-Activity Relationship | 1982 |
Oligouridylates as a template for nonenzymatic synthesis of oligoadenylates.
Topics: Adenine Nucleotides; Biological Evolution; Oligonucleotides; Oligoribonucleotides; Thermodynamics; Uracil Nucleotides | 1981 |
Chemical synthesis of an effective inhibitor of protein synthesis in eukaryotic cells: pppA2'-5'A2'-5'A and some analogues.
Topics: Adenine Nucleotides; Adenosine; Indicators and Reagents; Methods; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; Structure-Activity Relationship | 1980 |
Template-directed synthesis of oligoadenylate. Template effect of oligouridylates and catalytic activity of Pb2+ ion.
Topics: Adenine Nucleotides; Indicators and Reagents; Lead; Methods; Oligonucleotides; Oligoribonucleotides; Templates, Genetic; Uracil Nucleotides | 1980 |
2',5'-Oligo(A)-activated endoribonuclease. Tissue distribution and characterization with a binding assay.
Topics: Adenine Nucleotides; Animals; Cell Line; Endoribonucleases; HeLa Cells; Humans; Kidney; Kinetics; L Cells; Liver; Lymphocytes; Mice; Molecular Weight; Oligonucleotides; Oligoribonucleotides; Protein Binding; Reticulocytes; Ribonucleases; Species Specificity; Spleen; Tissue Distribution | 1981 |
An efficient chemical synthesis of adenylyl(2' goes to 5')adenylyl(2' goes to 5')adenosine [(2'-5')-oligo(A)].
Topics: Adenine Nucleotides; Chromatography, Thin Layer; Indicators and Reagents; Magnetic Resonance Spectroscopy; Oligonucleotides; Oligoribonucleotides | 1981 |
Chromatographic assay on DEAE-cellulose for (2'-5')-oligo(A) synthesis in cell extracts.
Topics: Adenine Nucleotides; Animals; Cell Line; Cells, Cultured; Chromatography, DEAE-Cellulose; Fibroblasts; HeLa Cells; Humans; Kinetics; L Cells; Magnesium; Male; Mice; Oligonucleotides; Oligoribonucleotides; RNA, Double-Stranded; Skin | 1981 |
Oligo(A), oligo(TG), and Alu repeats of DNA in chromatin are available for sequence-specific chemical modification with oligodeoxynucleotide derivatives.
Topics: Adenine Nucleotides; Base Sequence; Chromatin; DNA; Guanine Nucleotides; Molecular Sequence Data; Oligonucleotides; Oligoribonucleotides; Repetitive Sequences, Nucleic Acid; Thymine Nucleotides | 1994 |
A 2',5'-oligoadenylate analogue inhibits murine hepatitis virus strain 3 (MHV-3) replication in vitro but does not reduce MHV-3-related mortality or induction of procoagulant activity in susceptible mice.
Topics: Adenine Nucleotides; Alanine Transaminase; Animals; Antiviral Agents; Blood Coagulation Factors; Endoribonucleases; Enzyme Activation; Female; Hepatitis, Viral, Animal; Interferon-gamma; Mice; Mice, Inbred BALB C; Murine hepatitis virus; Oligonucleotides; Oligoribonucleotides; Th1 Cells; Virus Replication | 1995 |
Double and triple helix formation of 2'-5' and 3'-5' oligonucleotides.
Topics: Adenine Nucleotides; Circular Dichroism; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligonucleotides; Oligoribonucleotides; Poly U; Spectrophotometry, Ultraviolet; Thermodynamics; Uracil Nucleotides | 1993 |
Conformational changes in oligo-nucleotides upon binding to a peptide representing the N-terminal region of a viral coat protein. An optical spectroscopy study.
Topics: Adenine Nucleotides; Amino Acid Sequence; Base Composition; Capsid; Circular Dichroism; Hydrogen Bonding; Molecular Sequence Data; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Oligonucleotides; Oligoribonucleotides; Peptides; Plant Viruses; Poly dA-dT; Protein Binding; Thermodynamics | 1993 |
Targeting RNA decay with 2',5' oligoadenylate-antisense in respiratory syncytial virus-infected cells.
Topics: Adenine Nucleotides; Antiviral Agents; Binding Sites; Cell Line; Electrophoresis, Agar Gel; Endoribonucleases; Humans; Nucleic Acid Conformation; Oligonucleotides; Oligoribonucleotides; Polymerase Chain Reaction; Respiratory Syncytial Viruses; RNA, Antisense; RNA, Messenger; RNA, Viral; Viral Proteins; Virus Replication | 1997 |
2'-Deoxy-2'(S)-ethinyl oligonucleotides: a modification which selectively stabilizes oligoadenylate pairing to DNA complements.
Topics: Adenine Nucleotides; Base Sequence; DNA; Molecular Sequence Data; Oligonucleotides; Oligoribonucleotides | 1998 |
Conformational properties of 2',5' linked Rp- and Sp-phosphorothioate oligoadenylates studied by circular dichroism and NMR.
Topics: Adenine Nucleotides; Base Pairing; Chromatography, High Pressure Liquid; Circular Dichroism; Magnetic Resonance Spectroscopy; Molecular Conformation; Oligonucleotides; Oligoribonucleotides; Temperature; Thermodynamics | 2003 |
[VI International Congress of Comparative Pathology, Madrid, 4-11 May, 1952; oligo-elements and their deficiency in comparative pathology].
Topics: Adenine Nucleotides; Humans; Metabolism; Oligonucleotides; Oligoribonucleotides | 1952 |
Photochemistry of model oligo and poly-nucleotides. III. Cross-linking and staining properties of ultraviolet irradiated films of nucleic acids and oligonucleotides.
Topics: Adenine Nucleotides; Nucleic Acids; Nucleosides; Nucleotides; Oligonucleotides; Oligoribonucleotides; Staining and Labeling; Ultraviolet Rays | 1960 |
[Idea of oligo-elements in biology].
Topics: Adenine Nucleotides; Oligonucleotides; Oligoribonucleotides; Trace Elements | 1959 |
[Oligo-elements and alimentary hygiene].
Topics: Adenine Nucleotides; Folliculitis; Humans; Hygiene; Oligonucleotides; Oligoribonucleotides; Trace Elements | 1959 |
The properties of an oligo-1,4--1,4-glucantransferase from animal tissues.
Topics: Adenine Nucleotides; Glucosyltransferases; Oligonucleotides; Oligoribonucleotides | 1962 |
Hypochromicity of oligo- and polynucleotides.
Topics: Adenine Nucleotides; Nucleic Acids; Nucleosides; Nucleotides; Oligonucleotides; Oligoribonucleotides; Polynucleotides | 1962 |
[Oligo-elements in the white rat].
Topics: Adenine Nucleotides; Oligonucleotides; Oligoribonucleotides; Rats | 1951 |
Functional characterization of 2',5'-linked oligoadenylate binding determinant of human RNase L.
Topics: Adenine Nucleotides; Arginine; Crystallography, X-Ray; Dose-Response Relationship, Drug; Endoribonucleases; Enzyme Activation; Gene Deletion; Genetic Vectors; Glutathione Transferase; Humans; Hydrogen Bonding; Lysine; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Oligoribonucleotides; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Tryptophan | 2005 |
Small-molecule activators of RNase L with broad-spectrum antiviral activity.
Topics: Adenine Nucleotides; Animals; Antiviral Agents; Cell Line; Chromatography, High Pressure Liquid; Dimerization; Endoribonucleases; Enzyme Activation; Enzyme Activators; Fluorescence Resonance Energy Transfer; Immunity, Innate; Mice; Models, Molecular; Oligonucleotides; Oligoribonucleotides; Parainfluenza Virus 3, Human; Protein Binding; Protein Structure, Tertiary; Structure-Activity Relationship; Surface Plasmon Resonance; Virus Replication | 2007 |
Trimodal Control of Ion-Transport Activity on Cyclo-oligo-(1→6)-β-D-glucosamine-Based Artificial Ion-Transport Systems.
Topics: Adenine Nucleotides; Anions; Glucosamine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ion Transport; Oligonucleotides; Oligoribonucleotides | 2015 |