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2',5'-dideoxyadenosine and adenosine

2',5'-dideoxyadenosine has been researched along with adenosine in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199026 (74.29)18.7374
1990's8 (22.86)18.2507
2000's1 (2.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fain, JN; Li, SY; Moreno, FJ1
Cushing, DJ; Makujina, SR; Mustafa, SJ; Sabouni, MH1
Granger, HJ; Meininger, CJ1
Casolaro, V; Marone, G; Petracca, R; Vigorita, S1
Leoutsakos, A; Pearce, FL1
Church, MK; Hughes, PJ1
Shima, S1
Becker, BF; Gerlach, E; Heier, M; Nees, S; Newman, WH1
Bushfield, M; Johnson, RA; Shoshani, I; Stübner, D; Yeung, SM1
Reinhardt, RR; Wecker, L1
Brückner, R; Fenner, A; Meyer, W; Nobis, TM; Schmitz, W; Scholz, H1
Dorflinger, LJ; Schonbrunn, A1
García-Sáinz, JA; Torner, ML1
Anderson, RJ; Dillingham, MA1
Fredholm, BB; Jonzon, B; Lindström, K1
Miyamoto, T; Nishida, Y; Takeuchi, A1
Condorelli, M; Marone, G; Triggiani, M; Vigorita, S1
Braun, T; Onoda, JM; Wrenn, SM1
Anand-Srivastava, MB; Johnson, RA; Olaus, TH1
Church, MK; Holgate, ST; Hughes, PJ; Roath, S1
Burt, DS; Stanworth, DR1
McCarthy, L; Schimmel, RJ1
Hillyard, PA; Nials, AT; Skidmore, IF; Vardey, CJ1
McMahon, KK; Schimmel, RJ1
Agarwal, KC; Parks, RE2
Stone, TW1
Daly, JW; Law, J; Nimit, Y1
Agarwal, KC; Parks, RE; Russo, FX1
Johnson, RA; Shoshani, I1
Kennedy, TG; Yee, GM1
Ahlgren, SC; Levine, JD1
Bianchi, G; Cali, JJ; Désaubry, L; Iyengar, R; Johnson, RA; Krupinski, J; Lyons, E; Pieroni, JP; Shoshani, I; Taussig, R; Watson, PA1
Hazeki, O; Katada, T; Takasuga, S; Ui, M1
Babcock, DF; Carlson, AE; Conti, M; Hille, B; McKnight, GS; Schuh, SM1

Other Studies

35 other study(ies) available for 2',5'-dideoxyadenosine and adenosine

ArticleYear
Regulation of cyclic AMP metabolism and lipolysis in isolated rat fat cells by insulin, N6-(phenylisopropyl) adenosine and 2',5'-dideoxyadenosine.
    Journal of cyclic nucleotide research, 1979, Volume: 5, Issue:3

    Topics: Adenosine; Adipose Tissue; Animals; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Epinephrine; Female; Insulin; Lipolysis; Phenylisopropyladenosine; Rats

1979
Inhibition of adenylate cyclase attenuates adenosine receptor-mediated relaxation in coronary artery.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:2

    Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Colforsin; Coronary Vessels; Cyclic AMP; Dideoxyadenosine; Dilazep; Guanosine Triphosphate; In Vitro Techniques; Muscle Relaxation; Receptors, Purinergic; Sodium Fluoride; Swine; Vasodilator Agents

1991
Mechanisms leading to adenosine-stimulated proliferation of microvascular endothelial cells.
    The American journal of physiology, 1990, Volume: 258, Issue:1 Pt 2

    Topics: Adenosine; Animals; Biomechanical Phenomena; Cell Division; Cyclic AMP; Dideoxyadenosine; Dipyridamole; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypoxanthine; Hypoxanthines; Inosine; Isomerism; Microcirculation; Molecular Weight; Thioinosine

1990
Adenosine receptors of human leukocytes--II. Characterization of an inhibitory P-site.
    Biochemical pharmacology, 1990, Nov-01, Volume: 40, Issue:9

    Topics: Adenosine; Adenylyl Cyclases; Adult; Cells, Cultured; Cyclic AMP; Dideoxyadenosine; Enzyme Activation; Humans; Lymphocytes; Neutrophils; Purinergic Antagonists; Receptors, Purinergic; Vidarabine

1990
The effect of adenosine and its analogues on cyclic AMP changes and histamine secretion from rat peritoneal mast cells stimulated by various ligands.
    Biochemical pharmacology, 1986, Apr-15, Volume: 35, Issue:8

    Topics: Adenosine; Animals; Calcimycin; Concanavalin A; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Dipyridamole; Histamine Release; Immunoglobulin E; In Vitro Techniques; Ligands; Mast Cells; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Theophylline

1986
Inhibition of immunological and nonimmunological histamine release from human basophils by adenosine analogues that act at P-sites.
    Biochemical pharmacology, 1986, Jun-01, Volume: 35, Issue:11

    Topics: Adenosine; Basophils; Calcimycin; Cell Separation; Deoxyadenosines; Dideoxyadenosine; Histamine Release; Humans; Immune Sera; Immunoglobulin E; Kinetics; Vidarabine

1986
Inhibition by adenosine of ACTH-stimulated adenylate cyclase and steroidogenesis in the adrenal cortex.
    Molecular and cellular endocrinology, 1986, Volume: 47, Issue:1-2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Bucladesine; Deoxyadenosines; Dideoxyadenosine; Male; Phenylisopropyladenosine; Rats; Sodium Fluoride; Steroids

1986
Endothelium-mediated coronary dilatation by adenosine does not depend on endothelial adenylate cyclase activation: studies in isolated guinea pig hearts.
    Pflugers Archiv : European journal of physiology, 1988, Volume: 413, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Coronary Vessels; Cyclic AMP; Dideoxyadenosine; Dideoxynucleosides; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Guinea Pigs; Iloprost; In Vitro Techniques; Isoproterenol; Male; Receptors, Adrenergic, alpha; Vasodilation

1988
Cation and structural requirements for P site-mediated inhibition of adenylate cyclase.
    Molecular pharmacology, 1989, Volume: 35, Issue:5

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Brain; Colforsin; Deoxyadenine Nucleotides; Dideoxyadenosine; Dideoxynucleosides; Egtazic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Magnesium; Manganese; Receptors, Purinergic; Structure-Activity Relationship; Thionucleotides

1989
Adenosine inhibits choline kinase activity and decreases the phosphorylation of choline in striatal synaptosomes.
    Journal of neurochemistry, 1988, Volume: 50, Issue:6

    Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Choline; Choline Kinase; Corpus Striatum; Deoxyadenosines; Dideoxyadenosine; Kinetics; Male; Phosphorylation; Phosphorylcholine; Phosphotransferases; Rats; Rats, Inbred Strains; Synaptosomes

1988
Cardiac effects of adenosine and adenosine analogs in guinea-pig atrial and ventricular preparations: evidence against a role of cyclic AMP and cyclic GMP.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Cyclic AMP; Cyclic GMP; Deoxyadenosines; Dideoxyadenosine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Membrane Potentials; Myocardial Contraction; Papillary Muscles; Phenylisopropyladenosine

1985
Adenosine inhibits prolactin and growth hormone secretion in a clonal pituitary cell line.
    Endocrinology, 1985, Volume: 117, Issue:6

    Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Carbachol; Cell Line; Chromatography, High Pressure Liquid; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Dipyridamole; Growth Hormone; Phenylisopropyladenosine; Pituitary Gland; Pituitary Neoplasms; Prolactin; Rats; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide

1985
Rat fat-cells have three types of adenosine receptors (Ra, Ri and P). Differential effects of pertussis toxin.
    The Biochemical journal, 1985, Dec-01, Volume: 232, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adipose Tissue; Animals; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; In Vitro Techniques; Isoproterenol; Male; Pertussis Toxin; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Virulence Factors, Bordetella

1985
Purinergic regulation of basal and arginine vasopressin-stimulated hydraulic conductivity in rabbit cortical collecting tubule.
    The Journal of membrane biology, 1985, Volume: 88, Issue:3

    Topics: Adenosine; Adenylyl Cyclases; Animals; Arginine Vasopressin; Body Water; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; In Vitro Techniques; Kidney Tubules; Kidney Tubules, Collecting; Osmolar Concentration; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Ribose; Water-Electrolyte Balance

1985
Effect of adenosine receptor agonists and other compounds on cyclic AMP accumulation in forskolin-treated hippocampal slices.
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 332, Issue:2

    Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Hippocampus; Histamine; Isoproterenol; Male; Phenylisopropyladenosine; Prostaglandins E; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Xanthines

1986
Modulation of polymorphonuclear leukocyte function by adenosine analogues.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt A

    Topics: Adenosine; Chemotaxis, Leukocyte; Deoxyadenosines; Dideoxyadenosine; Humans; Kinetics; Neutrophils; Phagocytosis; Phenylisopropyladenosine; Reference Values; Superoxides; Thionucleosides

1986
Adenosine receptors on human lymphocytes.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Alprostadil; Binding Sites; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Histamine; Humans; In Vitro Techniques; Isoproterenol; Lymphocytes; Manganese; Neutrophils; Receptors, Purinergic; Theophylline; Vidarabine

1986
Characterization of the purine-reactive site of the rat testis cytosolic adenylate cyclase.
    Biochemical pharmacology, 1987, Jun-15, Volume: 36, Issue:12

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Cytosol; Deoxyadenosines; Dideoxyadenosine; Kinetics; Male; Phenylisopropyladenosine; Purines; Rats; Testis; Vidarabine

1987
Regulation of hepatocyte cAMP and pyruvate kinase by site-specific analogs of adenosine.
    Molecular and cellular endocrinology, 1982, Volume: 26, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenylyl Cyclases; Animals; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Epinephrine; Liver; Male; Phenylisopropyladenosine; Pyruvate Kinase; Rats; Rats, Inbred Strains

1982
The relationship between cyclic AMP changes and histamine release from basophil-rich human leucocytes.
    Biochemical pharmacology, 1983, Sep-01, Volume: 32, Issue:17

    Topics: Adenosine; Aged; Anemia; Basophils; Cell Separation; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Female; Histamine Release; Humans; Kinetics; Sodium Fluoride

1983
The effect of ribose and purine modified adenosine analogues on the secretion of histamine from rat mast cells induced by ionophore A23187.
    Biochemical pharmacology, 1983, Sep-15, Volume: 32, Issue:18

    Topics: Adenosine; Animals; Calcimycin; Deoxyadenosines; Dideoxyadenosine; Histamine Release; Immunoglobulin E; Male; Mast Cells; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Vidarabine

1983
Role of adenosine as an endogenous regulator of respiration in hamster brown adipocytes.
    The American journal of physiology, 1984, Volume: 246, Issue:3 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adipose Tissue, Brown; Animals; Cricetinae; Deoxyadenosines; Dideoxyadenosine; Isoproterenol; Lipolysis; Male; Mesocricetus; Oxygen Consumption

1984
Characterization of the adenosine receptor responsible for the inhibition of histamine and SRS-A release from human lung fragments.
    British journal of pharmacology, 1984, Volume: 83, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Deoxyadenosines; Dideoxyadenosine; Dipyridamole; Guinea Pigs; Hexobendine; Histamine Release; Humans; In Vitro Techniques; Lung; Receptors, Cell Surface; Receptors, Purinergic; SRS-A; Theophylline; Time Factors

1984
Inhibition of lipolysis and cyclic AMP accumulation by adenosine analogues in hamster epididymal adipocytes exposed to cholera toxin.
    Biochimica et biophysica acta, 1980, Dec-01, Volume: 633, Issue:2

    Topics: Adenosine; Adipose Tissue; Animals; Cholera Toxin; Clonidine; Cricetinae; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Epididymis; Lipolysis; Male; Phenylisopropyladenosine

1980
5'-Methylthioadenosine and 2',5'-dideoxyadenosine blockade of the inhibitory effects of adenosine on ADP-induced platelet aggregation by different mechanisms.
    Biochemical pharmacology, 1980, Sep-15, Volume: 29, Issue:18

    Topics: Adenosine; Adenosine Diphosphate; Adenylyl Cyclases; Blood Platelets; Deoxyadenosines; Dideoxyadenosine; Humans; In Vitro Techniques; Platelet Aggregation; Prostaglandins E; Thionucleosides

1980
Purine receptors involved in the depression of neuronal firing in cerebral cortex.
    Brain research, 1982, Sep-30, Volume: 248, Issue:2

    Topics: Adenosine; Adenosine Monophosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebral Cortex; Deoxyadenosines; Dideoxyadenosine; gamma-Aminobutyric Acid; Male; Neural Inhibition; Phenylisopropyladenosine; Rats; Receptors, Drug; Receptors, Purinergic

1982
Binding of 2',5'-dideoxyadenosine to brain membranes. Comparison to P-site inhibition of adenylate cyclase.
    Biochemical pharmacology, 1982, Oct-15, Volume: 31, Issue:20

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Binding Sites; Brain; Deoxyadenosines; Dideoxyadenosine; In Vitro Techniques; Kinetics; Membranes; Rats; Rats, Inbred Strains; Theophylline; Vidarabine

1982
Inhibition of human and rat platelet aggregation by extracts of Mo-er (Auricularia auricula).
    Thrombosis and haemostasis, 1982, Oct-29, Volume: 48, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Animals; Deoxyadenosines; Depression, Chemical; Dideoxyadenosine; Fungi; Humans; Plant Extracts; Platelet Aggregation; Rats; Rats, Inbred Strains; Thionucleosides

1982
Synergistic inhibition of platelet aggregation by forskolin plus PGE1 or 2-fluoroadenosine: effects of 2',5'-dideoxyadenosine and 5'-methylthioadenosine.
    Biochemical pharmacology, 1982, Nov-15, Volume: 31, Issue:22

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Alprostadil; Colforsin; Deoxyadenosines; Dideoxyadenosine; Diterpenes; Drug Synergism; Humans; In Vitro Techniques; Platelet Aggregation; Prostaglandins E; Thionucleosides

1982
Preparation and use of "P"-site-targeted affinity ligands for adenylyl cyclases.
    Methods in enzymology, 1994, Volume: 238

    Topics: Adenosine; Adenylyl Cyclases; Affinity Labels; Azides; Dideoxyadenosine; Indicators and Reagents; Isomerism; Kinetics; Ligands; Molecular Structure; Radioisotope Dilution Technique; Recombinant Proteins; Tritium

1994
Prostaglandin E2, cAMP and cAMP-dependent protein kinase isozymes during decidualization of rat endometrial stromal cells in vitro.
    Prostaglandins, 1993, Volume: 46, Issue:2

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Alkaline Phosphatase; Animals; Bucladesine; Cell Differentiation; Cells, Cultured; Cyclic AMP; Decidua; Dideoxyadenosine; Dinoprostone; Endometrium; Female; Isoenzymes; Kinetics; Protein Kinases; Rats; Rats, Sprague-Dawley

1993
Mechanical hyperalgesia in streptozotocin-diabetic rats.
    Neuroscience, 1993, Volume: 52, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenylate Cyclase Toxin; Animals; Diabetes Mellitus, Experimental; Dideoxyadenosine; Dinoprostone; GTP-Binding Proteins; Guanosine Diphosphate; Hyperalgesia; Indomethacin; Male; Mechanoreceptors; Pain; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Sensory Thresholds; Thionucleotides; Virulence Factors, Bordetella

1993
Isozyme-dependent sensitivity of adenylyl cyclases to P-site-mediated inhibition by adenine nucleosides and nucleoside 3'-polyphosphates.
    The Journal of biological chemistry, 1997, Apr-04, Volume: 272, Issue:14

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Brain; Calcium; Calmodulin; Cattle; Dideoxyadenosine; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gs; Isoenzymes; Membrane Proteins; Nerve Tissue Proteins; Oncogene Proteins; Rats; Recombinant Proteins; Structure-Activity Relationship

1997
Enhancement by adenosine of insulin-induced activation of phosphoinositide 3-kinase and protein kinase B in rat adipocytes.
    The Journal of biological chemistry, 1999, Jul-09, Volume: 274, Issue:28

    Topics: Adenosine; Adenosine Deaminase; Adipocytes; Animals; Dideoxyadenosine; Dinoprostone; Enzyme Activation; Insulin; Male; Phenylisopropyladenosine; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Second Messenger Systems; Xanthines

1999
Signaling pathways for modulation of mouse sperm motility by adenosine and catecholamine agonists.
    Biology of reproduction, 2006, Volume: 74, Issue:3

    Topics: Adenine; Adenosine; Adenylyl Cyclases; Animals; Calcium; Catecholamines; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Dideoxyadenosine; Enzyme Inhibitors; Imines; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein Kinase Inhibitors; Signal Transduction; Sperm Motility; Sperm Tail; Sulfonamides

2006