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2',3'-dideoxythymidine triphosphate and zidovudine

2',3'-dideoxythymidine triphosphate has been researched along with zidovudine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.79)18.7374
1990's14 (73.68)18.2507
2000's2 (10.53)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
August, EM; Brankovan, V; Ghazzouli, I; Hitchcock, MJ; Lin, TS; Mansuri, MM; Prusoff, WH; Sommadossi, JP; Starrett, JE; Sterzycki, RZ1
Ambrose, Z; Boyer, PL; Hughes, SH; Julias, JG; Liao, C; Marquez, VE; Meier, C; Vu, BC; Warnecke, S1
Goff, SP; Haseltine, W; Myrick, K; Prasad, VR1
Buckheit, RW; Germany, JM; Parker, WB; Ross, LJ; Secrist, JA; Shaddix, SC; Shannon, WM; Vince, R; White, EL1
Kemp, SD; Larder, BA; Lowe, DM; Parmar, V1
Aristoff, PA; Busso, M; Downey, KM; Palmer, JR; Poppe, SM; Resnick, L; Reusser, F; Romero, DL; So, AG; Tan, CK1
Izuta, S; Kojima, K; Sakurai, T; Saneyoshi, M; Suzuki, M; Yoshida, S1
Bernaerts, R; Holý, A; Hrebabecký, H; Merta, A; Otmar, M; Rosenberg, I; Votruba, I1
Boehme, RE; Chen, MS; Chernow, M; Chuang, RY; Marx, PA; Matthews, TR; McRoberts, MJ; Prisbe, EJ; Suttmann, RT; Wu, JC1
Macy, LJ; McCaleb, G; Parker, WB; Secrist, JA; Shaddix, SC; Shannon, WM; Vince, R; White, EL1
Bakhanashvili, M; Hizi, A1
Bakhanashvili, M; Boyer, PL; Hizi, A; Hughes, SH; Loya, S; Tal, R1
Mitsuya, H; Shirasaka, T; Ueno, T1
Clayton, DA; Eriksson, S; Xu, B1
Blackburn, EH; Strahl, C1
Brandi, G; Carnevali, A; Fraternale, A; Magnani, M; Rossi, L; Schiavano, GF1
Alcami, J; Alonso, C; González, CI; López, MC; Martín, F; Thomas, MC1
Cabodevilla, F; Martinez-Irujo, JJ; Santiago, E; Villahermosa, ML1
Guo, D; Jamburuthugoda, VK; Kim, B; Wedekind, JE1

Other Studies

19 other study(ies) available for 2',3'-dideoxythymidine triphosphate and zidovudine

ArticleYear
1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:2

    Topics: Antiviral Agents; Bone Marrow; Dideoxynucleosides; HIV; Stavudine; Thymidine; Zidovudine

1989
The nucleoside analogue D-carba T blocks HIV-1 reverse transcription.
    Journal of medicinal chemistry, 2009, Sep-10, Volume: 52, Issue:17

    Topics: Anti-HIV Agents; Base Sequence; Cell Line, Tumor; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Molecular Conformation; Pyrimidine Nucleosides; Reverse Transcriptase Inhibitors; Thymidine; Virus Replication

2009
Expression of enzymatically active reverse transcriptase of simian immunodeficiency virus in bacteria: sensitivity to nucleotide analogue inhibitors.
    Virology, 1990, Volume: 179, Issue:2

    Topics: Dideoxynucleotides; Escherichia coli; Gene Expression; Recombinant Fusion Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Simian Immunodeficiency Virus; Thymine Nucleotides; Zidovudine

1990
Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine and 3'-deoxythymidine. A novel RN
    The Journal of biological chemistry, 1991, Jan-25, Volume: 266, Issue:3

    Topics: Antiviral Agents; Base Sequence; Deoxyguanine Nucleotides; Dideoxynucleotides; DNA; DNA Polymerase I; DNA Polymerase II; DNA Polymerase III; HIV-1; Humans; In Vitro Techniques; Kinetics; Molecular Sequence Data; Reverse Transcriptase Inhibitors; RNA; Templates, Genetic; Thymine Nucleotides; Zidovudine

1991
Mutational analysis of two conserved sequence motifs in HIV-1 reverse transcriptase.
    FEBS letters, 1991, May-06, Volume: 282, Issue:2

    Topics: Amino Acid Sequence; Dideoxynucleotides; DNA Mutational Analysis; Foscarnet; HIV-1; In Vitro Techniques; Kinetics; Molecular Sequence Data; Phosphonoacetic Acid; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Thymine Nucleotides; Zidovudine

1991
Nonnucleoside reverse transcriptase inhibitors that potently and specifically block human immunodeficiency virus type 1 replication.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Oct-01, Volume: 88, Issue:19

    Topics: Animals; Antiviral Agents; Cell Survival; Dideoxynucleotides; DNA, Viral; Drug Synergism; HIV-1; Mice; Mice, Nude; Piperazines; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA, Viral; Thymine Nucleotides; Virus Replication; Zidovudine

1991
Mechanisms of inhibitions of DNA polymerase gamma by nucleotide analogues having anti-HIV activities.
    Nucleic acids symposium series, 1991, Issue:25

    Topics: Animals; Antiviral Agents; Cattle; Dideoxynucleotides; DNA Polymerase III; HIV; Male; Thymine Nucleotides; Zidovudine

1991
Inhibition of herpes simplex virus DNA polymerase by diphosphates of acyclic phosphonylmethoxyalkyl nucleotide analogues.
    Antiviral research, 1990, Volume: 13, Issue:5

    Topics: Acyclovir; Adenine; Antiviral Agents; Arabinofuranosylcytosine Triphosphate; Dideoxynucleotides; DNA Polymerase I; DNA Polymerase II; DNA Replication; HeLa Cells; Humans; Kinetics; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Thymine Nucleotides; Zidovudine

1990
Kinetics and inhibition of reverse transcriptase from human and simian immunodeficiency viruses.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:12

    Topics: Deoxyguanine Nucleotides; Dideoxynucleotides; HIV; Humans; Kinetics; Reverse Transcriptase Inhibitors; Simian Immunodeficiency Virus; Thymine Nucleotides; Zidovudine

1988
Comparison of the effect of Carbovir, AZT, and dideoxynucleoside triphosphates on the activity of human immunodeficiency virus reverse transcriptase and selected human polymerases.
    Biochemical and biophysical research communications, 1989, Jun-15, Volume: 161, Issue:2

    Topics: Deoxyguanine Nucleotides; Dideoxynucleosides; Dideoxynucleotides; DNA Primase; HIV; Humans; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; RNA Nucleotidyltransferases; Thymine Nucleotides; Zidovudine

1989
Interaction of the reverse transcriptase of human immunodeficiency virus type 1 with DNA.
    Biochemistry, 1994, Oct-11, Volume: 33, Issue:40

    Topics: Antiviral Agents; Autoradiography; Base Sequence; Benzodiazepines; Binding, Competitive; Dideoxynucleotides; DNA-Binding Proteins; DNA, Viral; Electrophoresis, Polyacrylamide Gel; HIV Reverse Transcriptase; HIV-1; Imidazoles; Molecular Sequence Data; Oligodeoxyribonucleotides; Quinolones; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Thymine Nucleotides; Zidovudine

1994
Enzymatic properties of two mutants of reverse transcriptase of human immunodeficiency virus type 1 (tyrosine 181-->isoleucine and tyrosine 188-->leucine), resistant to nonnucleoside inhibitors.
    AIDS research and human retroviruses, 1994, Volume: 10, Issue:8

    Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Catalysis; Deoxyguanine Nucleotides; Dideoxynucleotides; DNA, Viral; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Hot Temperature; Humans; Kinetics; Molecular Sequence Data; Mutation; Nevirapine; Phenanthrolines; Pyridines; Reverse Transcriptase Inhibitors; Ribonuclease H; RNA-Directed DNA Polymerase; Templates, Genetic; Thymine Nucleotides; Tyrosine; Zidovudine

1994
Enzymatic characterization of human immunodeficiency virus type 1 reverse transcriptase resistant to multiple 2',3'-dideoxynucleoside 5'-triphosphates.
    The Journal of biological chemistry, 1995, Oct-06, Volume: 270, Issue:40

    Topics: Antiviral Agents; Base Sequence; Binding Sites; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Dideoxynucleotides; DNA Primers; DNA, Viral; Drug Resistance, Multiple; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Thymine Nucleotides; Zidovudine

1995
Efficient incorporation of anti-HIV deoxynucleotides by recombinant yeast mitochondrial DNA polymerase.
    The Journal of biological chemistry, 1995, Aug-11, Volume: 270, Issue:32

    Topics: Antiviral Agents; Base Sequence; Deoxyribonucleotides; Dideoxynucleotides; DNA-Directed DNA Polymerase; HIV; Mitochondria; Molecular Sequence Data; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity; Thymine Nucleotides; Zidovudine

1995
The effects of nucleoside analogs on telomerase and telomeres in Tetrahymena.
    Nucleic acids research, 1994, Mar-25, Volume: 22, Issue:6

    Topics: Animals; Arabinonucleotides; Base Sequence; Cell Survival; Deoxyguanine Nucleotides; Dideoxynucleotides; DNA Nucleotidylexotransferase; Guanosine Triphosphate; Molecular Sequence Data; Nucleotides; Telomere; Tetrahymena thermophila; Thymine Nucleotides; Zidovudine

1994
Effect of antiviral treatments on the bone marrow in murine aids.
    Blood cells, molecules & diseases, 1995, Volume: 21, Issue:2

    Topics: Animals; Antiviral Agents; Bone Marrow; Dideoxynucleotides; Gene Products, gag; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Thymine Nucleotides; Zalcitabine; Zidovudine

1995
Reverse transcriptase-like activity in Trypanosoma cruzi.
    Acta tropica, 1997, Volume: 63, Issue:2-3

    Topics: Animals; Aphidicolin; Cell Nucleus; Cytoplasm; Dactinomycin; Dideoxynucleotides; Enzyme Inhibitors; Magnesium; Nucleic Acid Synthesis Inhibitors; Poly A; Poly C; Poly G; Poly T; Reverse Transcriptase Inhibitors; Rifamycins; RNA-Directed DNA Polymerase; RNA, Protozoan; Thymine Nucleotides; Transcription, Genetic; Trypanosoma; Zidovudine

1997
Synergistic inhibition of HIV-1 reverse transcriptase by combinations of chain-terminating nucleotides.
    Biochemistry, 1997, Oct-28, Volume: 36, Issue:43

    Topics: Anti-HIV Agents; Binding Sites; Dideoxynucleotides; DNA Primers; DNA Replication; DNA, Viral; Dose-Response Relationship, Drug; Drug Synergism; HIV Reverse Transcriptase; Oligodeoxyribonucleotides; Templates, Genetic; Thymine Nucleotides; Zidovudine

1997
Kinetic evidence for interaction of human immunodeficiency virus type 1 reverse transcriptase with the 3'-OH of the incoming dTTP substrate.
    Biochemistry, 2005, Aug-09, Volume: 44, Issue:31

    Topics: Acyclovir; Amino Acid Substitution; Asparagine; Dideoxynucleotides; Glutamine; HIV Reverse Transcriptase; Hydroxyl Radical; Isoleucine; Kinetics; Models, Molecular; Protein Binding; Substrate Specificity; Thymine Nucleotides; Valine; Zidovudine

2005