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2',3'-dideoxythymidine and zidovudine

2',3'-dideoxythymidine has been researched along with zidovudine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19909 (56.25)18.7374
1990's5 (31.25)18.2507
2000's1 (6.25)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balzarini, J; Bergstrom, DE; De Clercq, E; Mott, AW; Swartling, DJ1
August, EM; Brankovan, V; Ghazzouli, I; Lin, TS; Prusoff, WH; Shen, ZY; Yang, H1
Ahn, MK; Chu, CK; Gu, ZP; Schinazi, RF; Ullas, GV1
Baba, M; Balzarini, J; Broder, S; De Clercq, E; Herdewijn, P; Pauwels, R; Vanderhaeghe, H1
Chen, MS; Gao, YS; Ghazzouli, I; Lin, TS; McLaren, C; Prusoff, WH1
Boojamra, CG; Cihlar, T; Douglas, J; Grant, D; Hui, H; Kim, CU; Laflamme, G; Mackman, RL; Parrish, J; Prasad, V; Stoycheva, AD; Swaminathan, S; Wang, K; Zhang, L1
Li, Y; Liotta, DC; Liu, L; Lutz, S; Soni, PB; Zhang, X1
Kahn, J1
Armstrong, D; Chou, TC; Gold, JW; Kong, XB; Polsky, B; Ruprecht, RM; Watanabe, KA; Zeidler, JM; Zhu, QY1
Izuta, S; Kojima, K; Sakurai, T; Saneyoshi, M; Suzuki, M; Yoshida, S1
Yoshida, C; Yoshida, Y1
Broder, S; Kuno, S; Looney, DJ; Mitsuya, H; Ueno, R; Wong-Staal, F1
Broder, S; Cooney, DA; Hao, Z; Hartman, NR; Johns, DG; Mitsuya, H; Perno, CF; Webb, DS; Yarchoan, R1
Agrawal, KC; Beckman, BS; Gogu, SR1
Baba, M; De Clercq, E; Desmyter, J; Herdewijn, P; Pauwels, R; Vandeputte, M1
Hamamoto, Y; Matsuda, A; Matsui, T; Nakashima, H; Ueda, T; Yamamoto, N1

Reviews

1 review(s) available for 2',3'-dideoxythymidine and zidovudine

ArticleYear
Anti-human immunodeficiency virus therapeutics: now and the future.
    Seminars in liver disease, 1992, Volume: 12, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Dideoxynucleosides; HIV; HIV-1; Humans; Trichosanthin; Zalcitabine; Zidovudine

1992

Other Studies

15 other study(ies) available for 2',3'-dideoxythymidine and zidovudine

ArticleYear
3',3'-Difluoro-3'-deoxythymidine: comparison of anti-HIV activity to 3'-fluoro-3'-deoxythymidine.
    Journal of medicinal chemistry, 1992, Sep-04, Volume: 35, Issue:18

    Topics: Antiviral Agents; Dideoxynucleosides; HIV; Molecular Conformation; Structure-Activity Relationship

1992
Synthesis and antiviral activity of several 2,5'-anhydro analogues of 3'-azido-3'-deoxythymidine, 3'-azido-2',3'-dideoxyuridine, 3'-azido-2',3'-dideoxy-5-halouridines, and 3'-deoxythymidine against human immunodeficiency virus and Rauscher-murine leukemia
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:8

    Topics: Antiviral Agents; Chemical Phenomena; Chemistry; Deoxyuridine; HIV-1; Rauscher Virus; Thymidine

1989
Structure-activity relationships of pyrimidine nucleosides as antiviral agents for human immunodeficiency virus type 1 in peripheral blood mononuclear cells.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:3

    Topics: Antiviral Agents; Cell Division; Chemical Phenomena; Chemistry; HIV-1; Humans; Leukocytes, Mononuclear; Pyrimidine Nucleosides; Structure-Activity Relationship

1989
3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:8

    Topics: Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Deoxyribonucleosides; HIV; Humans; Structure-Activity Relationship; T-Lymphocytes; Virus Replication

1987
Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2',3'-unsaturated, and 2',3'-dideoxy analogues of pyrimidine deoxyribonucleosides against retroviruses.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:2

    Topics: Antiviral Agents; Cell Line; HIV; Indicators and Reagents; Magnetic Resonance Spectroscopy; Moloney murine leukemia virus; Pyrimidine Nucleosides; Spectrophotometry; Structure-Activity Relationship

1987
Synthesis, anti-HIV activity, and resistance profile of thymidine phosphonomethoxy nucleosides and their bis-isopropyloxymethylcarbonyl (bisPOC) prodrugs.
    Bioorganic & medicinal chemistry, 2007, Aug-15, Volume: 15, Issue:16

    Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; Magnetic Resonance Spectroscopy; Methane; Molecular Structure; Nucleosides; Organophosphorus Compounds; Prodrugs; Thymidine

2007
Synthesis of fluorescent nucleoside analogs as probes for 2'-deoxyribonucleoside kinases.
    Bioorganic & medicinal chemistry letters, 2010, Feb-01, Volume: 20, Issue:3

    Topics: Animals; Drosophila melanogaster; Fluorescent Dyes; Nucleosides; Phosphotransferases (Alcohol Group Acceptor)

2010
Synergistic inhibition of human immunodeficiency virus type 1 replication in vitro by two-drug and three-drug combinations of 3'-azido-3'-deoxythymidine, phosphonoformate, and 2',3'-dideoxythymidine.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:10

    Topics: Antiviral Agents; Cell Line; Cell Survival; Cell-Free System; Dideoxynucleosides; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Foscarnet; HIV-1; Humans; Phosphonoacetic Acid; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

1991
The 5'-triphosphates of 3'-azido-3'-deoxythymidine and 2', 3'-dideoxynucleosides inhibit DNA polymerase gamma by different mechanisms.
    Biochemical and biophysical research communications, 1991, Sep-16, Volume: 179, Issue:2

    Topics: Animals; Antiviral Agents; Base Sequence; Cattle; Dideoxynucleosides; Dideoxynucleotides; DNA Polymerase III; DNA, Single-Stranded; Electrophoresis, Polyacrylamide Gel; Male; Mitochondria; Molecular Sequence Data; Oligonucleotides; Testis; Thymine Nucleotides; Zidovudine

1991
Reversal of azidothymidine-induced bone marrow suppression by 2',3'-dideoxythymidine as studied by hemopoietic clonal culture.
    AIDS research and human retroviruses, 1990, Volume: 6, Issue:7

    Topics: Bone Marrow; Colony-Forming Units Assay; Dideoxynucleosides; Erythroid Precursor Cells; Granulocytes; Hematopoietic Stem Cells; Humans; Macrophages; Zidovudine

1990
Dextran sulfate suppression of viruses in the HIV family: inhibition of virion binding to CD4+ cells.
    Science (New York, N.Y.), 1988, Apr-29, Volume: 240, Issue:4852

    Topics: Antigens, Differentiation, T-Lymphocyte; Cell Line; Dextran Sulfate; Dextrans; Dideoxynucleosides; DNA, Viral; Fluorescent Antibody Technique; HIV; HIV Envelope Protein gp120; Immunologic Techniques; Retroviridae Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Suramin; T-Lymphocytes, Helper-Inducer; Thymidine; Viral Fusion Proteins; Virion; Zidovudine

1988
Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2'3'-dideoxythymidine (AZT) and other dideoxynucleoside
    The Journal of experimental medicine, 1989, Mar-01, Volume: 169, Issue:3

    Topics: Cells, Cultured; Colony-Stimulating Factors; Dideoxynucleosides; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; HIV-1; Humans; Lymphocytes; Monocytes; Stavudine; Virus Replication; Zidovudine

1989
Anti-HIV drugs: comparative toxicities in murine fetal liver and bone marrow erythroid progenitor cells.
    Life sciences, 1989, Volume: 45, Issue:4

    Topics: Animals; Antiviral Agents; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Dideoxynucleosides; Fetus; Hematopoietic Stem Cells; HIV; Liver; Mice; Ribavirin; Zalcitabine; Zidovudine

1989
Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro.
    Biochemical and biophysical research communications, 1987, Jan-15, Volume: 142, Issue:1

    Topics: Antigens, Viral; Antiviral Agents; Cell Line; Cell Survival; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Stavudine; Structure-Activity Relationship; Thymidine; Virus Replication; Zidovudine

1987
Inhibitory effect of 2',3'-didehydro-2',3'-dideoxynucleosides on infectivity, cytopathic effects, and replication of human immunodeficiency virus.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:6

    Topics: Antigens, Viral; Antiviral Agents; Cells, Cultured; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Stavudine; Thymidine; Viral Plaque Assay; Virus Replication; Zalcitabine; Zidovudine

1987