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2',3'-dideoxythymidine and thymidine

2',3'-dideoxythymidine has been researched along with thymidine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199024 (88.89)18.7374
1990's1 (3.70)18.2507
2000's1 (3.70)29.6817
2010's1 (3.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baba, M; Balzarini, J; Broder, S; De Clercq, E; Herdewijn, P; Pauwels, R; Vanderhaeghe, H1
Harano, A; Hatano, A; Nakagomi, Y; Naramoto, Y; Takigawa, Y; Toda, K; Yamada, H1
Li, Y; Liotta, DC; Liu, L; Lutz, S; Soni, PB; Zhang, X1
Koh, HY; Park, IS; Park, JK; Park, SD1
Hanaoka, F; Yamada, K; Yamada, M1
Broder, S; Kuno, S; Looney, DJ; Mitsuya, H; Ueno, R; Wong-Staal, F1
Baba, M; Balzarini, J; De Clerq, E; Herdewijn, P; Pauwels, R1
Broder, S; Mitsuya, H1
Baba, M; De Clercq, E; Desmyter, J; Herdewijn, P; Pauwels, R; Vandeputte, M1
Hamamoto, Y; Matsuda, A; Matsui, T; Nakashima, H; Ueda, T; Yamamoto, N1
Wainwright, LK; Wainwright, SD1
Ireland, CM; Stewart, BW1
Alexandre, H1
Amaudruz, F; Keyse, SM; Pidoux, M; Tyrrell, RM1
Licastro, F; Sarafian, T; Verity, AM; Walford, RL1
Evans, MJ; Huberman, JA; Hughes, RG; Manly, KF; Waqar, MA1
Bolles, CS; Bourguignon, GJ; Corombos, JD; Das, MR; Furmanski, P1
Day, RS; Mattern, MR; Paone, RF1
Cleaver, JE2
Collins, AR; Downes, CS; Johnson, RT1
Hanaoka, F; Kato, H; Yamada, K; Yamada, M1
McLennan, AG1
Charles, WC; Cleaver, JE1
Kumar, A; Nakatsugawa, S; Sugahara, T1
Mikuni, I1
Ben-Hur, E1

Other Studies

27 other study(ies) available for 2',3'-dideoxythymidine and thymidine

ArticleYear
3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:8

    Topics: Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Deoxyribonucleosides; HIV; Humans; Structure-Activity Relationship; T-Lymphocytes; Virus Replication

1987
Kinetic parameters and recognition of thymidine analogues with varying functional groups by thymidine phosphorylase.
    Bioorganic & medicinal chemistry, 2008, Apr-01, Volume: 16, Issue:7

    Topics: Kinetics; Molecular Structure; Structure-Activity Relationship; Substrate Specificity; Thymidine; Thymidine Phosphorylase

2008
Synthesis of fluorescent nucleoside analogs as probes for 2'-deoxyribonucleoside kinases.
    Bioorganic & medicinal chemistry letters, 2010, Feb-01, Volume: 20, Issue:3

    Topics: Animals; Drosophila melanogaster; Fluorescent Dyes; Nucleosides; Phosphotransferases (Alcohol Group Acceptor)

2010
DNA single stranded gaps formed during DNA repair synthesis induced by methyl methanesulfonate are filled by sequential action of aphidicolin- and dideoxythymidine sensitive DNA polymerases in HeLa cells.
    Cell biology and toxicology, 1991, Volume: 7, Issue:1

    Topics: Aphidicolin; Cells, Cultured; Dideoxynucleosides; Diterpenes; DNA Repair; DNA-Directed DNA Polymerase; DNA, Single-Stranded; HeLa Cells; Humans; Methyl Methanesulfonate; Thymidine

1991
Effects of aphidicolin and/or 2',3'-dideoxythymidine on DNA repair induced in HeLa cells by four types of DNA-damaging agents.
    The Journal of biological chemistry, 1985, Sep-05, Volume: 260, Issue:19

    Topics: Aphidicolin; Bleomycin; Dideoxynucleosides; Diterpenes; DNA Polymerase I; DNA Polymerase II; DNA Repair; HeLa Cells; Humans; Hydroxyurea; Kinetics; Sulfuric Acid Esters; Thymidine; Ultraviolet Rays; Zinostatin

1985
Dextran sulfate suppression of viruses in the HIV family: inhibition of virion binding to CD4+ cells.
    Science (New York, N.Y.), 1988, Apr-29, Volume: 240, Issue:4852

    Topics: Antigens, Differentiation, T-Lymphocyte; Cell Line; Dextran Sulfate; Dextrans; Dideoxynucleosides; DNA, Viral; Fluorescent Antibody Technique; HIV; HIV Envelope Protein gp120; Immunologic Techniques; Retroviridae Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Suramin; T-Lymphocytes, Helper-Inducer; Thymidine; Viral Fusion Proteins; Virion; Zidovudine

1988
Anti-retrovirus activity of 3'-fluoro- and 3'-azido-substituted pyrimidine 2',3'-dideoxynucleoside analogues.
    Biochemical pharmacology, 1988, Jul-15, Volume: 37, Issue:14

    Topics: Animals; Antimetabolites; Antiviral Agents; Cell Division; Deoxycytidine; Deoxycytidine Kinase; Dideoxynucleosides; DNA; HIV; Kinetics; Mice; Phosphorylation; Pyrimidine Nucleosides; Retroviridae; Thymidine; Thymidine Kinase; Zalcitabine

1988
Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:6

    Topics: Antiviral Agents; Carbohydrate Conformation; Cell Division; Cytopathogenic Effect, Viral; Deltaretrovirus; Deoxyadenosines; Deoxycytidine; Deoxyribonucleosides; Dideoxyadenosine; Dideoxynucleosides; Gene Products, gag; Humans; Lymphocyte Activation; Mitogens; Retroviridae Proteins; Structure-Activity Relationship; T-Lymphocytes; Thymidine; Vidarabine; Zalcitabine

1986
Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro.
    Biochemical and biophysical research communications, 1987, Jan-15, Volume: 142, Issue:1

    Topics: Antigens, Viral; Antiviral Agents; Cell Line; Cell Survival; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Stavudine; Structure-Activity Relationship; Thymidine; Virus Replication; Zidovudine

1987
Inhibitory effect of 2',3'-didehydro-2',3'-dideoxynucleosides on infectivity, cytopathic effects, and replication of human immunodeficiency virus.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:6

    Topics: Antigens, Viral; Antiviral Agents; Cells, Cultured; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Stavudine; Thymidine; Viral Plaque Assay; Virus Replication; Zalcitabine; Zidovudine

1987
Effects of some inhibitors of DNA synthesis and repair upon the cycle of serotonin N-acetyltransferase activity in cultured chick pineal glands.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 1986, Volume: 64, Issue:4

    Topics: Acetyltransferases; Animals; Aphidicolin; Arylamine N-Acetyltransferase; Benzamides; Cells, Cultured; Chickens; Circadian Rhythm; Cytarabine; Darkness; Deoxyadenosines; Dideoxynucleosides; Diterpenes; DNA Repair; DNA Replication; Kinetics; Light; Pineal Gland; Thymidine

1986
DNA-mediated gene transfer as an indicator of DNA damage and its repair by recipient cells.
    FEBS letters, 1987, Feb-09, Volume: 212, Issue:1

    Topics: Animals; Cytarabine; Dideoxynucleosides; DNA Damage; DNA Repair; L Cells; Methyl Methanesulfonate; Methylnitrosourea; Mice; Thymidine; Thymidine Kinase; Transfection

1987
Involvement of DNA-polymerase activities in mouse-blastocyst differentiation in vitro.
    Differentiation; research in biological diversity, 1985, Volume: 29, Issue:2

    Topics: Animals; Aphidicolin; Blastocyst; Cell Differentiation; Cells, Cultured; Dideoxynucleosides; Dideoxynucleotides; Diterpenes; DNA Polymerase I; DNA Polymerase II; DNA Replication; Female; Gonadotropins; Male; Mice; Thymidine; Thymine Nucleotides; Trophoblasts

1985
Excision repair in u.v. (254 nm) damaged non-dividing human skin fibroblasts: a major biological role for DNA polymerase alpha.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1985, Volume: 48, Issue:5

    Topics: Aphidicolin; Dideoxynucleosides; Diterpenes; DNA; DNA Polymerase II; DNA Repair; Fibroblasts; Humans; Skin; Thymidine; Ultraviolet Rays

1985
Inhibition of polymerases-alpha and -beta completely blocks DNA repair induced by UV irradiation in cultured mouse neuronal cells.
    Biochemical and biophysical research communications, 1985, Nov-15, Volume: 132, Issue:3

    Topics: Animals; Aphidicolin; Cells, Cultured; Dideoxynucleosides; Diterpenes; DNA; DNA Polymerase I; DNA Polymerase II; DNA Repair; Hydroxyurea; Mice; Mice, Inbred C57BL; Neurons; Thymidine; Ultraviolet Rays

1985
Effects of 2',3'-dideoxynucleosides on mammalian cells and viruses.
    Journal of cellular physiology, 1984, Volume: 121, Issue:2

    Topics: Animals; Cell Division; Cell Line; Cell Transformation, Viral; Cells, Cultured; Chlorocebus aethiops; Deoxyribonucleosides; Deoxyribonucleotides; Dideoxynucleosides; Kidney; Kinetics; Leukemia Virus, Murine; Mice; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Simplexvirus; Structure-Activity Relationship; Thymidine

1984
Inhibition by 2',3'-dideoxythymidine of retroviral infection of mouse and human cells.
    Cancer letters, 1980, Volume: 8, Issue:4

    Topics: Animals; Cell Division; Cell Transformation, Viral; Cells, Cultured; Dideoxynucleosides; Humans; Kirsten murine sarcoma virus; Mice; Rats; Retroviridae; Reverse Transcriptase Inhibitors; Thymidine

1980
Eukaryotic DNA repair is blocked at different steps by inhibitors of DNA topoisomerases and of DNA polymerases alpha and beta.
    Biochimica et biophysica acta, 1982, Apr-26, Volume: 697, Issue:1

    Topics: Cell Line; Colonic Neoplasms; Cytarabine; Dideoxynucleosides; DNA Polymerase I; DNA Polymerase II; DNA Repair; Humans; Kinetics; Nalidixic Acid; Novobiocin; Nucleic Acid Synthesis Inhibitors; Thymidine; Topoisomerase I Inhibitors

1982
Structure of repaired sites in human DNA synthesized in the presence of inhibitors of DNA polymerases alpha and beta in human fibroblasts.
    Biochimica et biophysica acta, 1983, Apr-15, Volume: 739, Issue:3

    Topics: Aphidicolin; Cells, Cultured; Cytarabine; Dideoxynucleosides; Diterpenes; DNA Polymerase I; DNA Polymerase II; DNA Repair; DNA Replication; Fibroblasts; Humans; Kinetics; Nucleic Acid Synthesis Inhibitors; Skin; Thymidine

1983
International Workshop on inhibition of DNA repair. King's College, Cambridge, U.K., 29th June-2nd July 1982.
    Mutation research, 1983, Volume: 112, Issue:2

    Topics: Animals; Aphidicolin; Arabinose; Dideoxynucleosides; Diterpenes; DNA Repair; Humans; Hydroxyurea; Thymidine

1983
Completion of excision repair patches in human cell preparations: identification of a probable mode of excision and resynthesis.
    Carcinogenesis, 1984, Volume: 5, Issue:3

    Topics: Aphidicolin; Cell Line; Cell Nucleus; Cytarabine; Dideoxynucleosides; Diterpenes; DNA Polymerase I; DNA Polymerase II; DNA Repair; DNA Replication; Fibroblasts; Humans; Thymidine; Ultraviolet Rays

1984
Unscheduled DNA synthesis in cell lysate system reflecting DNA repair in vivo.
    Cell structure and function, 1984, Volume: 9, Issue:4

    Topics: Cytarabine; Dideoxynucleosides; DNA; DNA Repair; HeLa Cells; Humans; Hydroxyurea; Thymidine; Ultraviolet Rays

1984
Effect of aphidicolin and 2',3'-dideoxythymidine on mitochondrial DNA replication.
    Biochemical and biophysical research communications, 1980, May-14, Volume: 94, Issue:1

    Topics: Animals; Aphidicolin; Cell Line; Cell Nucleus; Cricetinae; Cricetulus; Dideoxynucleosides; Diterpenes; DNA Polymerase I; DNA Polymerase II; DNA Polymerase III; DNA Replication; DNA, Mitochondrial; Kinetics; Lung; Mitochondria; Thymidine

1980
Comparison of nucleoid and alkaline sucrose gradients in the analysis of inhibitors of DNA repair in human fibroblasts.
    Biochemical and biophysical research communications, 1982, Jul-16, Volume: 107, Issue:1

    Topics: Aphidicolin; Benzamides; Cell Line; Cytarabine; Dideoxynucleosides; Diterpenes; DNA Polymerase I; DNA Polymerase II; DNA Repair; DNA Replication; DNA, Single-Stranded; Embryology; Fibroblasts; Humans; Hydroxyurea; Molecular Weight; Nucleic Acid Synthesis Inhibitors; Skin; Thymidine; Ultraviolet Rays

1982
Purine nucleoside analogues inhibit the repair of radiation-induced potentially lethal damage in mammalian cells in culture.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1982, Volume: 41, Issue:3

    Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Deoxycytidine; Deoxyguanosine; Deoxyuridine; Dideoxynucleosides; DNA Repair; Dose-Response Relationship, Drug; Purine Nucleosides; Thymidine; Vidarabine

1982
Posterior subcapsular cortical cataract by inhibitor on DNA replication.
    The Tokai journal of experimental and clinical medicine, 1980, Volume: 5, Issue:3

    Topics: Animals; Cataract; Culture Techniques; Cytarabine; Depression, Chemical; Dideoxynucleosides; DNA Replication; Epithelium; Lens, Crystalline; Male; Rats; Thymidine

1980
Enhanced radiation-induced killing of Chinese hamster cells by dideoxythymidine.
    Radiation research, 1981, Volume: 88, Issue:1

    Topics: Animals; Cell Cycle; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Dideoxynucleosides; DNA; DNA Polymerase I; DNA Repair; Dose-Response Relationship, Radiation; Fibroblasts; Gamma Rays; In Vitro Techniques; Radiation-Sensitizing Agents; Thymidine

1981