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2',3'-dideoxycytidinene and zidovudine

2',3'-dideoxycytidinene has been researched along with zidovudine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19907 (43.75)18.7374
1990's7 (43.75)18.2507
2000's2 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Horwitz, JP; Kessel, D; Meltsner, BR; Palomino, E1
Augustyns, K; Balzarini, J; Blaton, N; De Clercq, E; De Ranter, C; Everaert, D; Janssen, G; Jie, L; Peeters, O; Van Aerschot, A1
Baba, M; Balzarini, J; Broder, S; De Clercq, E; Herdewijn, P; Pauwels, R; Vanderhaeghe, H1
Chen, MS; Gao, YS; Ghazzouli, I; Lin, TS; McLaren, C; Prusoff, WH1
Antonenko, SV; Chentsova, NP; Kukhar, VP; Luik, AI; Poda, GI; Tetko, IV1
Chong, Y; Chu, CK; Gumina, G; Schinazi, RF; Wang, J; Zhou, W1
Töglhofer, W1
Chen, CH; Cheng, YC; Vazquez-Padua, M1
Darby, G; Larder, BA; Richman, DD1
Agrawal, KC; Beckman, BS; Gogu, SR1
Hiraoka, W; Kuwabara, M; Matsuda, A; Sato, F; Tanabe, K; Ueda, T1
Chen, MS; Kinney-Thomas, E; Lin, TS; Prusoff, WH; Schinazi, RF1
Hamamoto, Y; Matsuda, A; Matsui, T; Nakashima, H; Ueda, T; Yamamoto, N1
Anderson, KP; Azad, RF; Brown-Driver, V; Buckheit, RW1
Carr, A; Cooper, DA; Emery, S; Kelleher, A; Law, M1
Back, N; Bakker, M; Berkhout, B; de Ronde, A; Jebbink, MF; Jurriaans, S; Parkin, N; Reiss, P; van der Hoek, L1

Trials

1 trial(s) available for 2',3'-dideoxycytidinene and zidovudine

ArticleYear
CD8+ lymphocyte responses to antiretroviral therapy of HIV infection.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, Dec-01, Volume: 13, Issue:4

    Topics: Acetamides; Acetophenones; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; Humans; Lamivudine; Lymphocyte Count; Pyridines; Reverse Transcriptase Inhibitors; Ritonavir; Viral Load; Zalcitabine; Zidovudine

1996

Other Studies

15 other study(ies) available for 2',3'-dideoxycytidinene and zidovudine

ArticleYear
Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: AIDS Dementia Complex; Animals; Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Chemistry, Physical; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Kinetics; Molecular Structure; Phosphorylation; Pyrimidine Nucleosides; Rabbits; Stavudine; T-Lymphocytes; Thymidine Kinase; Thymus Gland; Zidovudine

1990
Synthesis and anti-HIV evaluation of 2',3'-dideoxyribo-5-chloropyrimidine analogues: reduced toxicity of 5-chlorinated 2',3'-dideoxynucleosides.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:6

    Topics: Antiviral Agents; Cell Line; Dideoxynucleosides; HIV; Humans; Molecular Conformation; X-Ray Diffraction

1990
3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:8

    Topics: Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Deoxyribonucleosides; HIV; Humans; Structure-Activity Relationship; T-Lymphocytes; Virus Replication

1987
Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2',3'-unsaturated, and 2',3'-dideoxy analogues of pyrimidine deoxyribonucleosides against retroviruses.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:2

    Topics: Antiviral Agents; Cell Line; HIV; Indicators and Reagents; Magnetic Resonance Spectroscopy; Moloney murine leukemia virus; Pyrimidine Nucleosides; Spectrophotometry; Structure-Activity Relationship

1987
HIV-1 reverse transcriptase inhibitor design using artificial neural networks.
    Journal of medicinal chemistry, 1994, Aug-05, Volume: 37, Issue:16

    Topics: Algorithms; Cell Line; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Structure; Neural Networks, Computer; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; T-Lymphocytes; Zidovudine

1994
Synthesis, structure-activity relationships, and drug resistance of beta-d-3'-fluoro-2',3'-unsaturated nucleosides as anti-HIV Agents.
    Journal of medicinal chemistry, 2004, Jun-17, Volume: 47, Issue:13

    Topics: Anti-HIV Agents; Drug Resistance, Viral; Drug Stability; HIV-1; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Models, Molecular; Molecular Conformation; Nucleosides; Structure-Activity Relationship

2004
[New, in Austria registered specialty drugs. Hivid (2',3'-dideoxycytidine; ddC)].
    Wiener klinische Wochenschrift, 1992, Volume: 104, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Animals; Antiviral Agents; Austria; CD4-Positive T-Lymphocytes; Humans; Leukocyte Count; Zalcitabine; Zidovudine

1992
Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity.
    Molecular pharmacology, 1991, Volume: 39, Issue:5

    Topics: Antiviral Agents; Cell Line; Cytarabine; Didanosine; Dideoxynucleosides; DNA, Mitochondrial; HIV; Humans; Lymphocyte Activation; Nucleosides; Stavudine; T-Lymphocytes; Zalcitabine; Zidovudine

1991
HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy.
    Science (New York, N.Y.), 1989, Mar-31, Volume: 243, Issue:4899

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Dideoxynucleosides; Drug Resistance; Foscarnet; HeLa Cells; HIV; HIV Core Protein p24; Humans; Microbial Sensitivity Tests; Phosphonoacetic Acid; Retroviridae Proteins; Reverse Transcriptase Inhibitors; Viral Plaque Assay; Virus Replication; Zalcitabine; Zidovudine

1989
Anti-HIV drugs: comparative toxicities in murine fetal liver and bone marrow erythroid progenitor cells.
    Life sciences, 1989, Volume: 45, Issue:4

    Topics: Animals; Antiviral Agents; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Dideoxynucleosides; Fetus; Hematopoietic Stem Cells; HIV; Liver; Mice; Ribavirin; Zalcitabine; Zidovudine

1989
Sensitization of X-irradiated Chinese hamster V79 cells by derivatives of pyrimidine nucleosides.
    Journal of radiation research, 1988, Volume: 29, Issue:4

    Topics: Animals; Antiviral Agents; Cell Count; Cell Line; Cell Survival; Dideoxynucleosides; Pyrimidine Nucleosides; Radiation-Sensitizing Agents; Stavudine; Zalcitabine; Zidovudine

1988
Antiviral activity of 2',3'-dideoxycytidin-2'-ene (2',3'-dideoxy-2',3'-didehydrocytidine) against human immunodeficiency virus in vitro.
    Biochemical pharmacology, 1987, Feb-01, Volume: 36, Issue:3

    Topics: Antiviral Agents; Deoxycytidine; Fluorescence; HIV; Humans; In Vitro Techniques; Monocytes; Thymidine; Zalcitabine; Zidovudine

1987
Inhibitory effect of 2',3'-didehydro-2',3'-dideoxynucleosides on infectivity, cytopathic effects, and replication of human immunodeficiency virus.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:6

    Topics: Antigens, Viral; Antiviral Agents; Cells, Cultured; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Stavudine; Thymidine; Viral Plaque Assay; Virus Replication; Zalcitabine; Zidovudine

1987
Antiviral activity of a phosphorothioate oligonucleotide complementary to human cytomegalovirus RNA when used in combination with antiviral nucleoside analogs.
    Antiviral research, 1995, Volume: 28, Issue:2

    Topics: Antiviral Agents; Base Sequence; Cell Line; Cytomegalovirus; Drug Interactions; Foscarnet; Ganciclovir; HIV-1; Humans; Molecular Sequence Data; Nucleic Acid Synthesis Inhibitors; RNA, Viral; Thionucleotides; Virus Replication; Zalcitabine; Zidovudine

1995
Increased multinucleoside drug resistance and decreased replicative capacity of a human immunodeficiency virus type 1 variant with an 8-amino-Acid insert in the reverse transcriptase.
    Journal of virology, 2005, Volume: 79, Issue:6

    Topics: Adult; Amino Acid Substitution; Anti-HIV Agents; Drug Resistance, Multiple, Viral; Evolution, Molecular; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Molecular Sequence Data; Mutation; Recombination, Genetic; Reverse Transcriptase Inhibitors; Sequence Analysis, DNA; Virus Replication; Zalcitabine; Zidovudine

2005