2',3'-dideoxycytidine 5'-triphosphate and zidovudine

2',3'-dideoxycytidine 5'-triphosphate has been researched along with zidovudine in 7 studies

Compound Research Comparison

Studies (2',3'-dideoxycytidine 5'-triphosphate)	Trials (2',3'-dideoxycytidine 5'-triphosphate)	Recent Studies (post-2010) (2',3'-dideoxycytidine 5'-triphosphate)	Studies (zidovudine)	Trials (zidovudine)	Recent Studies (post-2010) (zidovudine)
38	1	0	10,180	1,399	1,188

Protein Interaction Comparison

Protein	Taxonomy	zidovudine (IC50)
Thymidine kinase, cytosolic	Homo sapiens (human)	3
Reverse transcriptase/RNaseH	Human immunodeficiency virus 1	0.6633
Protease	Human immunodeficiency virus 1	0.015

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	6 (85.71)	18.2507
2000's	1 (14.29)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Amblard, F; Bassit, L; Bondada, L; Coats, SJ; Detorio, M; Grier, J; Hernandez-Santiago, BI; Koontz, D; Mellors, JW; Rapp, KL; Schinazi, RF; Sluis-Cremer, N	1
Chen, MS; Copeland, WC; Wang, TS	1
Eriksson, S; Törnevik, Y	1
Kraut, J; Kumar, A; Pelletier, H; Sawaya, MR; Wilson, SH	1
Gu, Z; Li, X; Parniak, MA; Quan, Y; Wainberg, MA	1
Aluigi, G; Brandi, G; Casabianca, A; Chiarantini, L; Fraternale, A; Magnani, M; Rossi, L; Schiavano, GF	1
Benatti, U; Brandi, G; Casabianca, A; De Flora, A; Fraternale, A; Magnani, M; Rossi, L	1

Reviews

1 review(s) available for 2',3'-dideoxycytidine 5'-triphosphate and zidovudine

Article	Year
Targeting antiviral nucleotide analogues to macrophages. Journal of leukocyte biology, 1997, Volume: 62, Issue:1 Topics: Animals; Antiviral Agents; Cats; Deoxycytosine Nucleotides; Dideoxynucleotides; Drug Carriers; Erythrocytes; HIV-1; Humans; Immunodeficiency Virus, Feline; Leukemia Virus, Murine; Macrophages; Mice; Murine Acquired Immunodeficiency Syndrome; Nucleotides; Thymine Nucleotides; Virus Replication; Zidovudine	1997

Article

Year

Targeting antiviral nucleotide analogues to macrophages.

Journal of leukocyte biology, 1997, Volume: 62, Issue:1

Topics: Animals; Antiviral Agents; Cats; Deoxycytosine Nucleotides; Dideoxynucleotides; Drug Carriers; Erythrocytes; HIV-1; Humans; Immunodeficiency Virus, Feline; Leukemia Virus, Murine; Macrophages; Mice; Murine Acquired Immunodeficiency Syndrome; Nucleotides; Thymine Nucleotides; Virus Replication; Zidovudine

1997

Other Studies

6 other study(ies) available for 2',3'-dideoxycytidine 5'-triphosphate and zidovudine

Article	Year
Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9 Topics: Anti-HIV Agents; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Molecular Structure; Reverse Transcriptase Inhibitors	2009
Human DNA polymerases alpha and beta are able to incorporate anti-HIV deoxynucleotides into DNA. The Journal of biological chemistry, 1992, Oct-25, Volume: 267, Issue:30 Topics: Antiviral Agents; Base Sequence; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA; DNA Polymerase I; DNA Polymerase II; HIV; Humans; Kinetics; Molecular Sequence Data; Terminator Regions, Genetic; Thymine Nucleotides; Zidovudine	1992
2',3'-Dideoxycytidine toxicity in cultured human CEM T lymphoblasts: effects of combination with 3'-azido-3'-deoxythymidine and thymidine. Molecular pharmacology, 1990, Volume: 38, Issue:2 Topics: Cell Division; Cell Line; Cell Survival; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Interactions; Humans; Phosphorylation; T-Lymphocytes; Thymidine; Zalcitabine; Zidovudine	1990
Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP. Science (New York, N.Y.), 1994, Jun-24, Volume: 264, Issue:5167 Topics: Animals; Base Sequence; Binding Sites; Crystallization; Crystallography, X-Ray; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA; DNA Polymerase I; DNA Primers; DNA-Directed RNA Polymerases; HIV Reverse Transcriptase; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Rats; Recombinant Proteins; RNA-Directed DNA Polymerase; Templates, Genetic; Thymine Nucleotides; Viral Proteins; Zidovudine	1994
Studies of neutralizing monoclonal antibody to human immunodeficiency virus type 1 reverse transcriptase: antagonistic and synergistic effects in reactions performed in the presence of nucleoside and nonnucleoside inhibitors, respectively. Journal of virology, 1996, Volume: 70, Issue:4 Topics: Animals; Antibodies, Monoclonal; Antiviral Agents; Delavirdine; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA; HIV Antibodies; HIV Reverse Transcriptase; Humans; Indoles; Mice; Neutralization Tests; Nevirapine; Peptide Chain Elongation, Translational; Piperazines; Pyridines; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Thymine Nucleotides; Zidovudine	1996
Inhibition of murine AIDS by combination of AZT and dideoxycytidine 5'-triphosphate. Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, Jun-01, Volume: 12, Issue:2 Topics: Animals; Antiviral Agents; Base Sequence; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA Primers; DNA, Viral; Drug Therapy, Combination; Female; Leukemia Virus, Murine; Lymph Nodes; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Murine Acquired Immunodeficiency Syndrome; Polymerase Chain Reaction; Proviruses; Spleen; Zidovudine	1996