2',3'-dideoxycytidine 5'-triphosphate and zalcitabine

2',3'-dideoxycytidine 5'-triphosphate has been researched along with zalcitabine in 11 studies

Compound Research Comparison

Studies (2',3'-dideoxycytidine 5'-triphosphate)	Trials (2',3'-dideoxycytidine 5'-triphosphate)	Recent Studies (post-2010) (2',3'-dideoxycytidine 5'-triphosphate)	Studies (zalcitabine)	Trials (zalcitabine)	Recent Studies (post-2010) (zalcitabine)
38	1	0	1,250	155	106
5	0	2	1,250	155	106

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (9.09)	18.7374
1990's	7 (63.64)	18.2507
2000's	3 (27.27)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Amblard, F; Bassit, L; Bondada, L; Coats, SJ; Detorio, M; Grier, J; Hernandez-Santiago, BI; Koontz, D; Mellors, JW; Rapp, KL; Schinazi, RF; Sluis-Cremer, N	1
Betageri, GV; Black, CD; Gartner, S; Parker, RJ; Popovic, M; Szebeni, J; Wahl, LM; Wahl, SM; Weinstein, JN	1
Eriksson, S; Törnevik, Y	1
Cheng, YC; Starnes, MC	1
Agrofoglio, LA; Faraj, A; Gosselin, G; Imbach, JL; Mathe, C; McPherson, S; Morrow, CD; Schinazi, RF; Sommadossi, JP; Wakefield, JK	1
Brandi, G; Chiarantini, L; Fraternale, A; Magnani, M; Rossi, L; Schiavano, GF	1
Baes, MI; Balzarini, J; De Groote, K; Declercq, PE; Naesens, L	1
Casabianca, A; Chiarantini, L; Magnani, M; Rossi, L; Schiavano, GF; Serafini, S; Vallanti, G	1
Bieth, A; Cazaux, C; Hoffmann, JS; Louat, T; Rols, MP; Servant, L; Teissie, J	1
Anderson, KS	1
Bonino, F; d'Urso, N; Ponzetto, A; Zahm, FE	1

Reviews

1 review(s) available for 2',3'-dideoxycytidine 5'-triphosphate and zalcitabine

Article	Year
Perspectives on the molecular mechanism of inhibition and toxicity of nucleoside analogs that target HIV-1 reverse transcriptase. Biochimica et biophysica acta, 2002, Jul-18, Volume: 1587, Issue:2-3 Topics: Anti-HIV Agents; Cytidine Triphosphate; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA Polymerase gamma; DNA-Directed DNA Polymerase; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Nucleosides; Reverse Transcriptase Inhibitors; Stereoisomerism; Zalcitabine	2002

Article

Year

Perspectives on the molecular mechanism of inhibition and toxicity of nucleoside analogs that target HIV-1 reverse transcriptase.

Biochimica et biophysica acta, 2002, Jul-18, Volume: 1587, Issue:2-3

Topics: Anti-HIV Agents; Cytidine Triphosphate; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA Polymerase gamma; DNA-Directed DNA Polymerase; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Nucleosides; Reverse Transcriptase Inhibitors; Stereoisomerism; Zalcitabine

2002

Trials

1 trial(s) available for 2',3'-dideoxycytidine 5'-triphosphate and zalcitabine

Article	Year
Inhibition of HIV-1 in monocyte/macrophage cultures by 2',3'-dideoxycytidine-5'-triphosphate, free and in liposomes. AIDS research and human retroviruses, 1990, Volume: 6, Issue:5 Topics: Acquired Immunodeficiency Syndrome; Antibodies; Antiviral Agents; Capsules; Cells, Cultured; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Deoxycytosine Nucleotides; Dideoxynucleotides; Drug Carriers; HIV-1; Humans; Immunoglobulin G; Kinetics; Liposomes; Macrophages; Monocytes; Virus Replication; Zalcitabine	1990

Article

Year

Inhibition of HIV-1 in monocyte/macrophage cultures by 2',3'-dideoxycytidine-5'-triphosphate, free and in liposomes.

AIDS research and human retroviruses, 1990, Volume: 6, Issue:5

Topics: Acquired Immunodeficiency Syndrome; Antibodies; Antiviral Agents; Capsules; Cells, Cultured; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Deoxycytosine Nucleotides; Dideoxynucleotides; Drug Carriers; HIV-1; Humans; Immunoglobulin G; Kinetics; Liposomes; Macrophages; Monocytes; Virus Replication; Zalcitabine

1990

Other Studies

9 other study(ies) available for 2',3'-dideoxycytidine 5'-triphosphate and zalcitabine

Article	Year
Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9 Topics: Anti-HIV Agents; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Molecular Structure; Reverse Transcriptase Inhibitors	2009
2',3'-Dideoxycytidine toxicity in cultured human CEM T lymphoblasts: effects of combination with 3'-azido-3'-deoxythymidine and thymidine. Molecular pharmacology, 1990, Volume: 38, Issue:2 Topics: Cell Division; Cell Line; Cell Survival; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Interactions; Humans; Phosphorylation; T-Lymphocytes; Thymidine; Zalcitabine; Zidovudine	1990
Cellular metabolism of 2',3'-dideoxycytidine, a compound active against human immunodeficiency virus in vitro. The Journal of biological chemistry, 1987, Jan-25, Volume: 262, Issue:3 Topics: Cell Line; Chromatography, High Pressure Liquid; Deoxycytidine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA; HIV; Humans; Kinetics; Nucleic Acid Synthesis Inhibitors; Phosphorylation; RNA; T-Lymphocytes; Zalcitabine	1987
Inhibition of human immunodeficiency virus type 1 reverse transcriptase by the 5'-triphosphate beta enantiomers of cytidine analogs. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:10 Topics: Antiviral Agents; Base Sequence; Cells, Cultured; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA; DNA Polymerase I; DNA, Mitochondrial; HIV Reverse Transcriptase; Molecular Sequence Data; Reverse Transcriptase Inhibitors; Stereoisomerism; Zalcitabine	1994
Inhibition of murine retrovirus-induced immunodeficiency disease by dideoxycytidine and dideoxycytidine 5'-triphosphate. Journal of acquired immune deficiency syndromes, 1993, Volume: 6, Issue:11 Topics: Administration, Oral; Animals; Antiviral Agents; Body Weight; Deoxycytosine Nucleotides; Dideoxynucleotides; Disease Models, Animal; Drug Carriers; Erythrocytes; Female; Gene Products, gag; Immunoblotting; Immunoglobulin G; Immunoglobulin M; Immunohistochemistry; Lactates; Lymph Nodes; Lymphocytes; Macrophages; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Retroviridae; Spleen; Zalcitabine	1993
Effects of 2',3'-dideoxycytidine and 2',3'-dideoxycytidine 5'-triphosphate on phospholipid metabolism in permeabilized rat hepatocytes. Biochemical pharmacology, 1997, Sep-15, Volume: 54, Issue:6 Topics: Animals; Cell Membrane Permeability; Cells, Cultured; Deoxycytosine Nucleotides; Dideoxynucleotides; Liver; Male; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Wistar; Zalcitabine	1997
Metabolism, mitochondrial uptake and toxicity of 2', 3'-dideoxycytidine. The Biochemical journal, 1999, Dec-15, Volume: 344 Pt 3 Topics: Animals; Biological Transport; Carnitine; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Cytidine Triphosphate; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA, Mitochondrial; Humans; Kinetics; Mitochondria, Liver; Rabbits; Rhodamine 123; U937 Cells; Zalcitabine	1999
Antitumor activity of 2',3'-dideoxycytidine nucleotide analog against tumors up-regulating DNA polymerase beta. Molecular pharmacology, 2001, Volume: 60, Issue:3 Topics: Animals; Antineoplastic Agents; Cell Division; Cell Extracts; Cell Survival; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA; DNA Polymerase beta; Enzyme Activation; Melanoma, Experimental; Mice; Neoplasm Transplantation; Simian virus 40; Tumor Cells, Cultured; Up-Regulation; Virus Replication; Zalcitabine	2001
Treatment of woodchuck hepatitis virus infection in vivo with 2', -3'-dideoxycytidine (ddC) and 2',-3'-dideoxycytidine monophosphate coupled to lactosaminated human serum albumin (L-HSA ddCMP). Liver, 1996, Volume: 16, Issue:2 Topics: Animals; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA, Viral; Drug Carriers; Female; Hepatitis B; Hepatitis B Virus, Woodchuck; Male; Marmota; Serum Albumin; Viremia; Virus Replication; Zalcitabine	1996