Compounds > 2',3'-dideoxycytidine 5'-triphosphate
Page last updated: 2024-09-03

2',3'-dideoxycytidine 5'-triphosphate and lamivudine

2',3'-dideoxycytidine 5'-triphosphate has been researched along with lamivudine in 4 studies

Compound Research Comparison

Studies
(2',3'-dideoxycytidine 5'-triphosphate)		Trials
(2',3'-dideoxycytidine 5'-triphosphate)		Recent Studies (post-2010)
(2',3'-dideoxycytidine 5'-triphosphate)		Studies
(lamivudine)		Trials
(lamivudine)		Recent Studies (post-2010) (lamivudine)
38107,0251,4252,177
5027,0251,4252,177

Protein Interaction Comparison

ProteinTaxonomy2',3'-dideoxycytidine 5'-triphosphate (IC50)lamivudine (IC50)
Capsid protein Hepatitis B virus0.1

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amblard, F; Bassit, L; Bondada, L; Coats, SJ; Detorio, M; Grier, J; Hernandez-Santiago, BI; Koontz, D; Mellors, JW; Rapp, KL; Schinazi, RF; Sluis-Cremer, N1
Anderson, KS; Feng, JY2
Anderson, KS1

Reviews

1 review(s) available for 2',3'-dideoxycytidine 5'-triphosphate and lamivudine

ArticleYear
Perspectives on the molecular mechanism of inhibition and toxicity of nucleoside analogs that target HIV-1 reverse transcriptase.
    Biochimica et biophysica acta, 2002, Jul-18, Volume: 1587, Issue:2-3

    Topics: Anti-HIV Agents; Cytidine Triphosphate; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA Polymerase gamma; DNA-Directed DNA Polymerase; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Nucleosides; Reverse Transcriptase Inhibitors; Stereoisomerism; Zalcitabine

2002

Other Studies

3 other study(ies) available for 2',3'-dideoxycytidine 5'-triphosphate and lamivudine

ArticleYear
Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9

    Topics: Anti-HIV Agents; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Molecular Structure; Reverse Transcriptase Inhibitors

2009
Mechanistic studies comparing the incorporation of (+) and (-) isomers of 3TCTP by HIV-1 reverse transcriptase.
    Biochemistry, 1999, Jan-05, Volume: 38, Issue:1

    Topics: Anti-HIV Agents; Binding Sites; Deoxycytidine Monophosphate; Deoxycytosine Nucleotides; Deoxyribonucleosides; Dideoxynucleotides; DNA Primers; DNA, Viral; HIV Reverse Transcriptase; Hydrolysis; Kinetics; Lamivudine; Models, Molecular; Ribonuclease H; RNA, Viral; Stereoisomerism; Templates, Genetic

1999
Mechanistic studies examining the efficiency and fidelity of DNA synthesis by the 3TC-resistant mutant (184V) of HIV-1 reverse transcriptase.
    Biochemistry, 1999, Jul-20, Volume: 38, Issue:29

    Topics: Amino Acid Substitution; Deoxycytidine Monophosphate; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Dideoxynucleotides; DNA Primers; DNA, Viral; Drug Resistance, Microbial; HIV Reverse Transcriptase; Humans; Kinetics; Lamivudine; RNA, Viral; Templates, Genetic; Thermodynamics; Valine

1999