2',3'-dideoxyadenosine triphosphate has been researched along with didanosine in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 7 (43.75) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| abu Sheikha, G; Cappellacci, L; de Montis, A; Franchetti, P; Grifantini, M; La Colla, P; Loi, AG; Messini, L; Spiga, MG; Tramontano, E | 1 |
| Amblard, F; Bassit, L; Bondada, L; Coats, SJ; Detorio, M; Grier, J; Hernandez-Santiago, BI; Koontz, D; Mellors, JW; Rapp, KL; Schinazi, RF; Sluis-Cremer, N | 1 |
| Nair, V; Sells, TB | 1 |
| Fridland, A; Johnson, MA | 1 |
| Ahluwalia, G; Broder, S; Cooney, DA; Dalal, M; Flora, KP; Fridland, A; Hao, Z; Johns, DG; Mitsuya, H | 1 |
| Balzarini, J; Eschbach, A; Halazy, S; Navé, JF; Wolff-Kugel, D | 1 |
| López, M; Mayol, N; Vázquez-Padua, MA | 1 |
| Boyer, PL; Hughes, SH; Lisziewicz, J; Lori, F | 1 |
| Beuneu, C; Buc, H; Lemaire, G; Lepoivre, M; Roux, P; Roy, B | 1 |
| Back, DJ; Barry, MG; Henry-Mowatt, JS; Hoggard, PG; Kewn, S; Sales, SD; Veal, GJ | 1 |
| Agrofoglio, LA; Cahours, X; Kieda, C; Mesplet, N; Morin, P; Tran, TT | 1 |
| Cupo, A; Dellamonica, P; Durant, J; Duval, D; Ettesse, H; Guedj, R; Le Saint, C; Terreux, R; Vincent, JP | 1 |
| Boretto, J; Canard, B; Courcambeck, J; Deval, J; Garrido-Urbani, S; Halfon, P; Navarro, JM; Selmi, B; Sire, J | 1 |
| Babusis, D; Durand-Gasselin, L; Flaherty, JF; Hawkins, T; Ray, AS; Reddy, YS; Veikley, W | 1 |
| Baev, D; Cahn, P; Calarota, SA; De Forni, D; Katabira, E; Lori, F; Maserati, R; Rakhmanova, A; Stevens, MR; Testori, M | 1 |
| Gang, L; Huilin, G; Lan, X; Lvjiang, H; Mingdao, L; Wei, G; Yan, Z | 1 |
2 trial(s) available for 2',3'-dideoxyadenosine triphosphate and didanosine
| Article | Year |
|---|---|
Intracellular nucleotide levels during coadministration of tenofovir disoproxil fumarate and didanosine in HIV-1-infected patients.
Topics: Adenine; Adult; Aged; Anti-HIV Agents; Chromatography, Liquid; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Didanosine; Dideoxynucleotides; Female; HIV Infections; Humans; Male; Middle Aged; Nucleotides; Organophosphonates; Tandem Mass Spectrometry; Tenofovir; Young Adult | 2011 |
VS411 reduced immune activation and HIV-1 RNA levels in 28 days: randomized proof-of-concept study for antiviral-hyperactivation limiting therapeutics.
Topics: Adult; Analysis of Variance; Anti-HIV Agents; Biomarkers; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Delayed-Action Preparations; Deoxyadenine Nucleotides; Didanosine; Dideoxynucleotides; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; HIV Infections; HIV-1; Humans; Immunomodulation; Male; Placebos; RNA, Viral; Urea; Viral Load | 2012 |
14 other study(ies) available for 2',3'-dideoxyadenosine triphosphate and didanosine
| Article | Year |
|---|---|
Synthesis and evaluation of the anti-HIV activity of aza and deaza analogues of isoddA and their phosphates as prodrugs.
Topics: Adenosine Triphosphate; Antiviral Agents; Aza Compounds; Dideoxyadenosine; Dideoxynucleotides; HIV Reverse Transcriptase; HIV-1; HIV-2; Molecular Structure; Phosphates; Recombinant Proteins; Reverse Transcriptase Inhibitors | 1994 |
Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.
Topics: Anti-HIV Agents; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Molecular Structure; Reverse Transcriptase Inhibitors | 2009 |
Interpretation of the roles of adenylosuccinate lyase and of AMP deaminase in the anti-HIV activity of 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine.
Topics: Adenosine; Adenylosuccinate Lyase; AMP Deaminase; Deoxyadenine Nucleotides; Didanosine; Dideoxyadenosine; Dideoxynucleotides; HIV; Succinates | 1992 |
Phosphorylation of 2',3'-dideoxyinosine by cytosolic 5'-nucleotidase of human lymphoid cells.
Topics: 5'-Nucleotidase; Adenosine Triphosphate; Deoxyadenine Nucleotides; Didanosine; Dideoxynucleosides; Dideoxynucleotides; Dinucleoside Phosphates; Humans; In Vitro Techniques; Inosine Monophosphate; Kinetics; Nucleotidases; Phosphorylation; T-Lymphocytes | 1989 |
Initial studies on the cellular pharmacology of 2',3'-dideoxyinosine, an inhibitor of HIV infectivity.
Topics: Alanine; Animals; Cell Line; Chromatography, High Pressure Liquid; Deoxyadenine Nucleotides; Deoxyribonucleotides; Didanosine; Dideoxynucleotides; HIV; Inosine; Nucleotides; T-Lymphocytes | 1987 |
Enzymatic phosphorylation and pyrophosphorylation of 2',3'-dideoxyadenosine-5'-monophosphate, a key metabolite in the pathway for activation of the anti-HIV (human immunodeficiency virus) agent 2',3'-dideoxyinosine.
Topics: Adenosine Triphosphate; Adenylate Kinase; Animals; Biotransformation; Deoxyadenine Nucleotides; Didanosine; Dideoxynucleotides; Escherichia coli; HIV; Kinetics; Phosphorylation; Rats; Ribose-Phosphate Pyrophosphokinase; Substrate Specificity | 1994 |
Uptake and distribution of 2',3'-dideoxyinosine and its derivatives in a human monocytoid cell line.
Topics: Biological Transport; Biotransformation; Cell Division; Deoxyadenine Nucleotides; Didanosine; Dideoxynucleotides; DNA Damage; DNA Replication; DNA, Neoplasm; Humans; Lymphoma, Large B-Cell, Diffuse; Monocytes; RNA, Neoplasm; Tumor Cells, Cultured; Zidovudine | 1995 |
Analysis of amino insertion mutations in the fingers subdomain of HIV-1 reverse transcriptase.
Topics: Anti-HIV Agents; Deoxyadenine Nucleotides; Didanosine; Dideoxynucleotides; Drug Resistance, Microbial; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Mutagenesis, Insertional; Protein Conformation | 1999 |
Simultaneous determination of pyrimidine or purine deoxyribonucleoside triphosphates using a polymerase assay.
Topics: Anti-HIV Agents; Base Sequence; Cell Line; Chromatography, High Pressure Liquid; Deoxyadenine Nucleotides; Deoxyribonucleotides; Didanosine; Dideoxynucleotides; DNA Polymerase I; DNA Primers; Humans; Lymphocytes; Sensitivity and Specificity | 1999 |
Intracellular activation of 2',3'-dideoxyinosine and drug interactions in vitro.
Topics: Anti-HIV Agents; Deoxyadenine Nucleotides; Didanosine; Dideoxynucleotides; Drug Interactions; Guanosine; Humans; Hydroxyurea; Inosine; Intracellular Fluid; Lamivudine; Pentoxifylline; Stavudine; U937 Cells; Zidovudine | 1999 |
Analysis of intracellular didanosine triphosphate at sub-ppb level using LC-MS/MS.
Topics: Cells, Cultured; Chromatography, Liquid; Deoxyadenine Nucleotides; Didanosine; Dideoxynucleotides; Humans; Radioimmunoassay; Reproducibility of Results; Solutions; Spectrometry, Mass, Electrospray Ionization | 2001 |
Determination of ddATP levels in human immunodeficiency virus-infected patients treated with dideoxyinosine.
Topics: Anti-HIV Agents; Antibodies; Biotransformation; Chromatography, Ion Exchange; Deoxyadenine Nucleotides; Didanosine; Dideoxynucleotides; HIV Infections; Humans; Hydrolysis; In Vitro Techniques; Leukocyte Count; Models, Molecular; Neutrophils; Phosphorylation; Radioimmunoassay | 2004 |
A loss of viral replicative capacity correlates with altered DNA polymerization kinetics by the human immunodeficiency virus reverse transcriptase bearing the K65R and L74V dideoxynucleoside resistance substitutions.
Topics: Cells, Cultured; Deoxyadenine Nucleotides; Didanosine; Dideoxynucleotides; DNA Replication; Drug Resistance, Viral; HIV Reverse Transcriptase; Humans; Kinetics; Mutation; Virus Replication | 2004 |
Simultaneous determination of 2',3'-dideoxyinosine and the active metabolite, 2',3'-dideoxyadenosine-5'-triphosphate in human peripheral-blood mononuclear cell by HPLC-MS/MS and the application to cell pharmacokinetics.
Topics: Adult; Anti-HIV Agents; Chromatography, High Pressure Liquid; Deoxyadenine Nucleotides; Didanosine; Dideoxynucleotides; HIV Infections; Humans; Limit of Detection; Middle Aged; Reproducibility of Results; Tandem Mass Spectrometry | 2015 |