2--3--dialdehyde-atp and carboxyatractyloside

2--3--dialdehyde-atp has been researched along with carboxyatractyloside* in 1 studies

Other Studies

1 other study(ies) available for 2--3--dialdehyde-atp and carboxyatractyloside

Article	Year
Affinity modification of creatine kinase and ATP-ADP translocase in heart mitochondria: determination of their molar stoichiometry. Biochemical and biophysical research communications, 1986, Jan-14, Volume: 134, Issue:1 Oxidized dialdehyde analogs of ADP or ATP (oADP and oATP) were shown to inhibit irreversibly adenine nucleotide translocator (T) and creatine kinase (CK) in heart mitochondria. Inactivation of T and CK was parallel with carboxyatractyloside - sensitive and (ADP + phosphocreatine) - sensitive incorporation of o[3H]ADP into mitochondria, respectively. o[3H]ADP incorporation sensitive to CAT or ADP+phosphocreatine was used to determine T and CK contents in mitochondria. T content in cardiac mitochondria from rat, rabbit, dog, and chicken was calculated to be 2.6 - 2.9 moles/mole cyt.aa3. The same value of T/cyt.aa3 ratio was found in liver mitochondria with lower cytochrome aa3 content. In all types of cardiac mitochondria CK content was found to be 2.4 - 2.6 moles/mole cyt.aa3. The data show that T and CK are present in molar ratio 1:1 in all types of cardiac mitochondria. Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Atractyloside; Carrier Proteins; Chickens; Creatine Kinase; Dogs; Kinetics; Mitochondria, Heart; Mitochondrial ADP, ATP Translocases; Nucleotidyltransferases; Rabbits; Rats	1986

Article

Year

Affinity modification of creatine kinase and ATP-ADP translocase in heart mitochondria: determination of their molar stoichiometry.

Biochemical and biophysical research communications, 1986, Jan-14, Volume: 134, Issue:1

Oxidized dialdehyde analogs of ADP or ATP (oADP and oATP) were shown to inhibit irreversibly adenine nucleotide translocator (T) and creatine kinase (CK) in heart mitochondria. Inactivation of T and CK was parallel with carboxyatractyloside - sensitive and (ADP + phosphocreatine) - sensitive incorporation of o[3H]ADP into mitochondria, respectively. o[3H]ADP incorporation sensitive to CAT or ADP+phosphocreatine was used to determine T and CK contents in mitochondria. T content in cardiac mitochondria from rat, rabbit, dog, and chicken was calculated to be 2.6 - 2.9 moles/mole cyt.aa3. The same value of T/cyt.aa3 ratio was found in liver mitochondria with lower cytochrome aa3 content. In all types of cardiac mitochondria CK content was found to be 2.4 - 2.6 moles/mole cyt.aa3. The data show that T and CK are present in molar ratio 1:1 in all types of cardiac mitochondria.

Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Atractyloside; Carrier Proteins; Chickens; Creatine Kinase; Dogs; Kinetics; Mitochondria, Heart; Mitochondrial ADP, ATP Translocases; Nucleotidyltransferases; Rabbits; Rats

1986