Compounds > 2-(phenylmethyl)-1-naphthol
Page last updated: 2024-09-04

2-(phenylmethyl)-1-naphthol and masoprocol

2-(phenylmethyl)-1-naphthol has been researched along with masoprocol in 3 studies

Compound Research Comparison

Studies
(2-(phenylmethyl)-1-naphthol)		Trials
(2-(phenylmethyl)-1-naphthol)		Recent Studies (post-2010)
(2-(phenylmethyl)-1-naphthol)		Studies
(masoprocol)		Trials
(masoprocol)		Recent Studies (post-2010) (masoprocol)
900138063

Protein Interaction Comparison

ProteinTaxonomy2-(phenylmethyl)-1-naphthol (IC50)masoprocol (IC50)
RNA polymerase beta subunit (EC 2.7.7.6), partialEscherichia coli12.4362
90-kda heat shock protein beta HSP90 beta, partialHomo sapiens (human)2.6232
Estrogen receptor 1Homo sapiens (human)22.1937
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonasePlasmodium berghei61.65
heat shock protein HSP 90-alpha isoform 2Homo sapiens (human)2.6232
Proto-oncogene c-FosHomo sapiens (human)0.0079
Transcription factor AP-1Homo sapiens (human)0.0079
Insulin-like growth factor 1 receptorHomo sapiens (human)0.9
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)2.12
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)0.2915
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 22.59
AromataseHomo sapiens (human)0.011
Polyunsaturated fatty acid 5-lipoxygenaseRattus norvegicus (Norway rat)0.752
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)0.11
17-beta-hydroxysteroid dehydrogenase type 1Homo sapiens (human)5.5
Polyunsaturated fatty acid lipoxygenase ALOX15Homo sapiens (human)1.5114
Polyunsaturated fatty acid lipoxygenase ALOX12Homo sapiens (human)2.778
17-beta-hydroxysteroid dehydrogenase type 2Homo sapiens (human)0.38
Alpha-synucleinHomo sapiens (human)0.215
Polyunsaturated fatty acid 5-lipoxygenaseMus musculus (house mouse)0.4
Leukotriene B4 receptor 1Homo sapiens (human)0.085
Lipoxygenase Glycine max (soybean)4.865
5-lipoxygenase Bos taurus (cattle)0.7
large T antigenBetapolyomavirus macacae21.86

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kreft, AF; Musser, JH1
Batt, DG; Galbraith, W; Harris, RR; Maynard, GD; Petraitis, JJ; Shaw, JE1
Izumi, A; Matsumoto, H; Miki, T; Nihro, Y; Satoh, T; Sogawa, S; Ueda, H1

Reviews

1 review(s) available for 2-(phenylmethyl)-1-naphthol and masoprocol

ArticleYear
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.
    Journal of medicinal chemistry, 1992, Jul-10, Volume: 35, Issue:14

    Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases; Neutrophils; Quinolines

1992

Other Studies

2 other study(ies) available for 2-(phenylmethyl)-1-naphthol and masoprocol

ArticleYear
2-substituted-1-naphthols as potent 5-lipoxygenase inhibitors with topical antiinflammatory activity.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Chemical Phenomena; Chemistry; Dermatitis; Ear Diseases; Edema; Leukemia, Basophilic, Acute; Lipoxygenase Inhibitors; Molecular Structure; Naphthols; Rats; Structure-Activity Relationship; Tumor Cells, Cultured

1990
3,4-Dihydroxychalcones as potent 5-lipoxygenase and cyclooxygenase inhibitors.
    Journal of medicinal chemistry, 1993, Nov-26, Volume: 36, Issue:24

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Cell Line; Chalcone; Chalcones; Cyclooxygenase Inhibitors; Edema; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred ICR; Molecular Structure; Sheep; Structure-Activity Relationship

1993