Page last updated: 2024-09-04

2-(phenylmethyl)-1-naphthol and lonapalene

2-(phenylmethyl)-1-naphthol has been researched along with lonapalene in 3 studies

Compound Research Comparison

Studies (2-(phenylmethyl)-1-naphthol)	Trials (2-(phenylmethyl)-1-naphthol)	Recent Studies (post-2010) (2-(phenylmethyl)-1-naphthol)	Studies (lonapalene)	Trials (lonapalene)	Recent Studies (post-2010) (lonapalene)
9	0	0	18	2	1

Protein Interaction Comparison

Protein	Taxonomy	2-(phenylmethyl)-1-naphthol (IC50)	lonapalene (IC50)
Polyunsaturated fatty acid 5-lipoxygenase	Rattus norvegicus (Norway rat)		0.6467
5-lipoxygenase	Bos taurus (cattle)		0.5

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Batt, DG; Collins, RJ; Corbett, RL; Green, AM; Harris, RR; Wadman, EA; Wright, SW	1
Kreft, AF; Musser, JH	1
Batt, DG; Galbraith, W; Harris, RR; Maynard, GD; Petraitis, JJ; Shaw, JE	1

Reviews

1 review(s) available for 2-(phenylmethyl)-1-naphthol and lonapalene

Article	Year
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors. Journal of medicinal chemistry, 1992, Jul-10, Volume: 35, Issue:14 Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases; Neutrophils; Quinolines	1992

Other Studies

2 other study(ies) available for 2-(phenylmethyl)-1-naphthol and lonapalene

Article	Year
Novel 1-(pyridylphenyl)-1-phenyl-2-imidazolylethanols with topical antiinflammatory activity. Journal of medicinal chemistry, 1992, Aug-21, Volume: 35, Issue:17 Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Calcimycin; Cyclooxygenase Inhibitors; Dermatitis; Edema; Imidazoles; Lipoxygenase Inhibitors; Male; Mice; Molecular Structure; Phospholipases A; Pyridines; Structure-Activity Relationship; Tetradecanoylphorbol Acetate	1992
2-substituted-1-naphthols as potent 5-lipoxygenase inhibitors with topical antiinflammatory activity. Journal of medicinal chemistry, 1990, Volume: 33, Issue:1 Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Chemical Phenomena; Chemistry; Dermatitis; Ear Diseases; Edema; Leukemia, Basophilic, Acute; Lipoxygenase Inhibitors; Molecular Structure; Naphthols; Rats; Structure-Activity Relationship; Tumor Cells, Cultured	1990

Article

Year

Novel 1-(pyridylphenyl)-1-phenyl-2-imidazolylethanols with topical antiinflammatory activity.

Journal of medicinal chemistry, 1992, Aug-21, Volume: 35, Issue:17

Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Calcimycin; Cyclooxygenase Inhibitors; Dermatitis; Edema; Imidazoles; Lipoxygenase Inhibitors; Male; Mice; Molecular Structure; Phospholipases A; Pyridines; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1992

2-substituted-1-naphthols as potent 5-lipoxygenase inhibitors with topical antiinflammatory activity.

Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Chemical Phenomena; Chemistry; Dermatitis; Ear Diseases; Edema; Leukemia, Basophilic, Acute; Lipoxygenase Inhibitors; Molecular Structure; Naphthols; Rats; Structure-Activity Relationship; Tumor Cells, Cultured

1990