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2-(n,n-dipropyl)amino-6,7-dihydroxytetralin and 2-(n,n-dipropyl)amino-5,6-dihydroxytetralin

2-(n,n-dipropyl)amino-6,7-dihydroxytetralin has been researched along with 2-(n,n-dipropyl)amino-5,6-dihydroxytetralin in 7 studies

Compound Research Comparison

Studies
(2-(n,n-dipropyl)amino-6,7-dihydroxytetralin)
Trials
(2-(n,n-dipropyl)amino-6,7-dihydroxytetralin)
Recent Studies (post-2010)
(2-(n,n-dipropyl)amino-6,7-dihydroxytetralin)
Studies
(2-(n,n-dipropyl)amino-5,6-dihydroxytetralin)
Trials
(2-(n,n-dipropyl)amino-5,6-dihydroxytetralin)
Recent Studies (post-2010) (2-(n,n-dipropyl)amino-5,6-dihydroxytetralin)
11003700

Protein Interaction Comparison

ProteinTaxonomy2-(n,n-dipropyl)amino-6,7-dihydroxytetralin (IC50)2-(n,n-dipropyl)amino-5,6-dihydroxytetralin (IC50)
DRattus norvegicus (Norway rat)0.1355
D(3) dopamine receptorRattus norvegicus (Norway rat)0.1355
D(1B) dopamine receptorRattus norvegicus (Norway rat)0.1355
D(4) dopamine receptorRattus norvegicus (Norway rat)0.1355
D(2) dopamine receptorRattus norvegicus (Norway rat)0.1355

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batink, H; de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B1
Broekkamp, CL; Gower, AJ1
Hoyng, PF; Thörig, L; Timmermans, PB; van Zwieten, PA1
Feenstra, MG; Goedemoed, JH; Horn, AS; Rollema, H1
Feenstra, MG; Horn, AS; Westerink, BH; Wirix, E1
Bradbury, AJ; Costall, B; Naylor, RJ1
Feenstra, MG; Horn, AS; Mulder, TB; Rollema, H; Westerink, BH1

Other Studies

7 other study(ies) available for 2-(n,n-dipropyl)amino-6,7-dihydroxytetralin and 2-(n,n-dipropyl)amino-5,6-dihydroxytetralin

ArticleYear
Quantitative relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cell Membrane; Clonidine; Kinetics; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Vasoconstriction

1984
Dopaminergic agents including 3-PPP and its enantiomers on medial septal self-stimulation.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Appetite Depressants; Benzazepines; Dextroamphetamine; Drug Interactions; Haloperidol; Male; Nomifensine; Piperidines; Rats; Receptors, Dopamine; Self Stimulation; Stereoisomerism; Sulpiride; Tetrahydronaphthalenes

1985
M-7 lowers rabbit intraocular pressure.
    Ophthalmic research, 1985, Volume: 17, Issue:6

    Topics: Animals; Depression, Chemical; Dopamine; Female; Intraocular Pressure; Male; Naphthols; Rabbits; Sympatholytics; Tetrahydronaphthalenes

1985
Possible anomalous behaviour of apomorphine in relation to other dopamine receptor agonists.
    The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:7

    Topics: Adenylyl Cyclases; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Corpus Striatum; Female; Homovanillic Acid; Levodopa; Rats; Rats, Inbred Strains; Receptors, Dopamine; Tetrahydronaphthalenes

1983
Certain dopamine agonists increase dopamine synthesis in the striatum of rat brain.
    European journal of pharmacology, 1984, Jun-01, Volume: 101, Issue:3-4

    Topics: 4-Butyrolactone; Animals; Cerebral Cortex; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Female; Haloperidol; Kinetics; Olfactory Bulb; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes

1984
Inhibition and facilitation of motor responding of the mouse by actions of dopamine agonists in the forebrain.
    Neuropharmacology, 1984, Volume: 23, Issue:9

    Topics: Animals; Brain; Dopamine; Injections; Male; Methysergide; Mice; Motor Activity; Nucleus Accumbens; Sympatholytics; Tetrahydronaphthalenes

1984
Amperometric detection of low concentrations of dopamine receptor agonists after liquid chromatographic on-column sample enrichment: effect of o-methylation on brain concentrations of dipropyl-5,6-ADTN and dipropyl-6,7-ADTN.
    Life sciences, 1983, Jan-31, Volume: 32, Issue:5

    Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Microchemistry; Naphthalenes; Rats; Tetrahydronaphthalenes

1983