2-(n,n-dimethylamino)-6,7-dihydroxytetralin has been researched along with yohimbine in 9 studies
| Studies (2-(n,n-dimethylamino)-6,7-dihydroxytetralin) | Trials (2-(n,n-dimethylamino)-6,7-dihydroxytetralin) | Recent Studies (post-2010) (2-(n,n-dimethylamino)-6,7-dihydroxytetralin) | Studies (yohimbine) | Trials (yohimbine) | Recent Studies (post-2010) (yohimbine) |
|---|---|---|---|---|---|
| 46 | 0 | 0 | 5,893 | 253 | 532 |
| Protein | Taxonomy | 2-(n,n-dimethylamino)-6,7-dihydroxytetralin (IC50) | yohimbine (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0353 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 1.02 | |
| D(2) dopamine receptor | Homo sapiens (human) | 2.06 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0428 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0466 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.126 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0682 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0682 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0682 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.013 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.126 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.074 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 1.689 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moulds, RF; Stevens, MJ | 1 |
| Cannon, JG; Hicks, PE | 1 |
| Bendesky, RJ; Jones, JH; Martin, GE | 1 |
| Horn, AS; Mulder, AH; Sminia, P; Van Oene, JC | 1 |
| Baldwin, JJ; Martin, GE; McClure, DE; Watling, KJ; Williams, M | 1 |
| Arnerić, SP; Chow, SA; Fischer, LJ; Long, JP | 1 |
| De Jonge, A; Thoolen, MJ; Timmermans, PB; Van Zwieten, PA; Wilffert, B | 1 |
| Fallon, S; Liebman, JM; Pastor, G; Welch, JJ | 1 |
| Burke, JA; Chang, FW; Potter, DE | 1 |
9 other study(ies) available for 2-(n,n-dimethylamino)-6,7-dihydroxytetralin and yohimbine
| Article | Year |
|---|---|
Antagonism by nifedipine of alpha-1 and alpha-2 adrenoceptor-mediated responses of human digital arteries.
Topics: Electric Stimulation; Fingers; Humans; In Vitro Techniques; Methoxamine; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Tetrahydronaphthalenes; Tritium; Vasoconstriction; Yohimbine | 1986 |
Cardiovascular effects of 2-(NN-dimethyl)amino-6,7-dihydroxy-1,2,3,4 tetrahydronaphthalene in pithed rats: differential antagonism by yohimbine and prazosin.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Male; Naphthols; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Tetrahydronaphthalenes; Yohimbine | 1980 |
Different actions of TL-99 and 3-PPP in producing contraversive turning in the 6-OHDA-lesioned rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Apomorphine; Female; Hydroxydopamines; Motor Activity; Naphthalenes; Oxidopamine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra; Tetrahydronaphthalenes; Yohimbine | 1983 |
The purported dopamine agonist DPI inhibits [3H]noradrenaline release from rat cortical slices but not [3H]dopamine and [14C]acetylcholine release from rat striatal slices in-vitro.
Topics: Acetylcholine; Animals; Catecholamines; Cerebral Cortex; Corpus Striatum; Dopamine; Imidazolines; In Vitro Techniques; Male; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes; Yohimbine | 1983 |
Interaction of the component enantiomers of the putative dopamine autoreceptor agonist, TL-99 (6,7-dihydroxy-2-dimethylamino tetralin) with dopaminergic systems in mammalian brain and teleost retina.
Topics: Adrenergic alpha-Agonists; Animals; Apomorphine; Brain; Female; Fishes; Male; Mice; Motor Activity; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Dopamine; Retina; Spiperone; Stereoisomerism; Sulpiride; Tetrahydronaphthalenes; Yohimbine | 1983 |
Inhibition of insulin release from rat pancreatic islets by drugs that are analogues of dopamine.
Topics: Adrenal Medulla; Animals; Apomorphine; Cells, Cultured; Dopamine; Epinephrine; Ergolines; Glucose; Indans; Insulin; Insulin Antagonists; Insulin Secretion; Islets of Langerhans; Male; Pergolide; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes; Yohimbine | 1984 |
Heterogeneity of the interaction between alpha 1- and alpha 2-adrenoceptor agonists with their respective receptors in the vascular system of the pithed rat.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Cocaine; Dopamine; Electric Stimulation; Emetics; Ethanolamines; Hemodynamics; Male; Naphthols; Prazosin; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetrahydronaphthalenes; Yohimbine | 1984 |
Postsynaptic dopamine agonist properties of TL-99 are revealed by yohimbine co-treatment.
Topics: Animals; Male; Motor Activity; Naphthalenes; Piperidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Rotation; Tetrahydronaphthalenes; Yohimbine | 1983 |
Effects of aminotetralins on intraocular pressure and pupillary function in rabbits.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Intraocular Pressure; Male; Naphthalenes; Pupil; Rabbits; Receptors, Dopamine; Sulpiride; Tetrahydronaphthalenes; Yohimbine | 1984 |