2-(n,n-dimethylamino)-6,7-dihydroxytetralin has been researched along with spiperone in 4 studies
| Studies (2-(n,n-dimethylamino)-6,7-dihydroxytetralin) | Trials (2-(n,n-dimethylamino)-6,7-dihydroxytetralin) | Recent Studies (post-2010) (2-(n,n-dimethylamino)-6,7-dihydroxytetralin) | Studies (spiperone) | Trials (spiperone) | Recent Studies (post-2010) (spiperone) |
|---|---|---|---|---|---|
| 46 | 0 | 0 | 2,944 | 13 | 85 |
| Protein | Taxonomy | 2-(n,n-dimethylamino)-6,7-dihydroxytetralin (IC50) | spiperone (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0008 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.097 | |
| D(4) dopamine receptor | Homo sapiens (human) | 0.0005 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.097 | |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | 0.097 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.0635 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.097 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0001 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.955 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baldwin, JJ; Martin, GE; McClure, DE; Watling, KJ; Williams, M | 1 |
| Haubrich, DR; Martin, GE; Williams, M | 1 |
| De Vries, J; Dijkstra, D; Horn, AS; Mulder, AH | 1 |
| Totaro, JA; Williams, M | 1 |
4 other study(ies) available for 2-(n,n-dimethylamino)-6,7-dihydroxytetralin and spiperone
| Article | Year |
|---|---|
Interaction of the component enantiomers of the putative dopamine autoreceptor agonist, TL-99 (6,7-dihydroxy-2-dimethylamino tetralin) with dopaminergic systems in mammalian brain and teleost retina.
Topics: Adrenergic alpha-Agonists; Animals; Apomorphine; Brain; Female; Fishes; Male; Mice; Motor Activity; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Dopamine; Retina; Spiperone; Stereoisomerism; Sulpiride; Tetrahydronaphthalenes; Yohimbine | 1983 |
A pharmacological comparison of 6,7-dihydroxy-2-dimethylaminotetralin (TL-99) and N-n-propyl-3-(3-hydroxyphenyl)piperidine with (3-PPP) selected dopamine agonists.
Topics: 4-Butyrolactone; Animals; Apomorphine; Cell Membrane; Corpus Striatum; Female; Humans; Hydroxydopamines; Naphthalenes; Oxidopamine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Tetrahydronaphthalenes | 1982 |
Is TL-99 a selective presynaptic dopamine receptor agonist?
Topics: Acetylcholine; Animals; Corpus Striatum; Dopamine; Female; Fluphenazine; Male; Motor Activity; Naphthalenes; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Tetrahydronaphthalenes; Time Factors | 1982 |
Interaction of the putative dopamine autoreceptor agonists 3-PPP and TL-99 with [3H]apomorphine binding sites in rat striatal membranes.
Topics: Animals; Apomorphine; Binding Sites; Binding, Competitive; Corpus Striatum; In Vitro Techniques; Kinetics; Membranes; Naphthalenes; Piperidines; Rats; Receptors, Dopamine; Spiperone; Tetrahydronaphthalenes | 1982 |