2-(n,n-dimethylamino)-6,7-dihydroxytetralin has been researched along with pergolide in 4 studies
| Studies (2-(n,n-dimethylamino)-6,7-dihydroxytetralin) | Trials (2-(n,n-dimethylamino)-6,7-dihydroxytetralin) | Recent Studies (post-2010) (2-(n,n-dimethylamino)-6,7-dihydroxytetralin) | Studies (pergolide) | Trials (pergolide) | Recent Studies (post-2010) (pergolide) |
|---|---|---|---|---|---|
| 46 | 0 | 0 | 845 | 123 | 87 |
| Protein | Taxonomy | 2-(n,n-dimethylamino)-6,7-dihydroxytetralin (IC50) | pergolide (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.379 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.385 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.264 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.2 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.111 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.385 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.064 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 1.41 | |
| D | Rattus norvegicus (Norway rat) | 0.0031 | |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0031 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.2 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.041 | |
| D(2) dopamine receptor | Bos taurus (cattle) | 0.0603 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.679 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.041 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.041 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.513 | |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0031 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.014 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.379 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.2 | |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | 0.385 | |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0031 | |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | 0.385 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.385 | |
| 5-hydroxytryptamine receptor 6 | Rattus norvegicus (Norway rat) | 0.385 | |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus (Norway rat) | 0.385 | |
| 5-hydroxytryptamine receptor 5A | Rattus norvegicus (Norway rat) | 0.385 | |
| 5-hydroxytryptamine receptor 5B | Rattus norvegicus (Norway rat) | 0.385 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.0054 | |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | 0.385 | |
| Alpha-synuclein | Homo sapiens (human) | 7.9 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.076 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.039 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0031 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.1202 | |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | 0.385 | |
| D | Bos taurus (cattle) | 0.0603 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.385 | |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | 0.385 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brusniak, MY; DuRand, C; Ginsburg, B; Neve, KA; Pearlman, RS; Starr, S; Teeter, M; Tseng, T; Wilcox, RE | 1 |
| Claustre, Y; Fage, D; Scatton, B; Zivkovic, B | 1 |
| Arnerić, SP; Chow, SA; Fischer, LJ; Long, JP | 2 |
4 other study(ies) available for 2-(n,n-dimethylamino)-6,7-dihydroxytetralin and pergolide
| Article | Year |
|---|---|
CoMFA-based prediction of agonist affinities at recombinant D1 vs D2 dopamine receptors.
Topics: Animals; Binding Sites; Databases, Factual; Dopamine Agonists; Humans; Ligands; Macaca mulatta; Models, Molecular; Molecular Conformation; Protein Structure, Secondary; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; Recombinant Proteins; Structure-Activity Relationship; Tumor Cells, Cultured | 1998 |
Relative selectivity of 6,7-dihydroxy-2-dimethylaminotetralin, N-n-propyl-3-(3-hydroxyphenyl)piperidine, N-n-propylnorapomorphine and pergolide as agonists at striatal dopamine autoreceptors and postsynaptic dopamine receptors.
Topics: Acetylcholine; Animals; Apomorphine; Corpus Striatum; Dihydroxyphenylalanine; Ergolines; Haloperidol; Homovanillic Acid; Male; Naphthalenes; Pergolide; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Sodium Oxybate; Tetrahydronaphthalenes; Tyrosine 3-Monooxygenase | 1985 |
Dopamine analog-induced hyperglycemia in rats: involvement of the adrenal medulla and the endocrine pancreas.
Topics: Adrenal Medulla; Animals; Apomorphine; Blood Glucose; Bromocriptine; Dextroamphetamine; Dihydroxyphenylalanine; Dopamine; Ergolines; Indans; Insulin; Islets of Langerhans; Male; Pergolide; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Tetrahydronaphthalenes | 1984 |
Inhibition of insulin release from rat pancreatic islets by drugs that are analogues of dopamine.
Topics: Adrenal Medulla; Animals; Apomorphine; Cells, Cultured; Dopamine; Epinephrine; Ergolines; Glucose; Indans; Insulin; Insulin Antagonists; Insulin Secretion; Islets of Langerhans; Male; Pergolide; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes; Yohimbine | 1984 |