Compounds > 2-(n,n-dimethylamino)-6,7-dihydroxytetralin
Page last updated: 2024-09-03

2-(n,n-dimethylamino)-6,7-dihydroxytetralin and nifedipine

2-(n,n-dimethylamino)-6,7-dihydroxytetralin has been researched along with nifedipine in 3 studies

Compound Research Comparison

Studies
(2-(n,n-dimethylamino)-6,7-dihydroxytetralin)		Trials
(2-(n,n-dimethylamino)-6,7-dihydroxytetralin)		Recent Studies (post-2010)
(2-(n,n-dimethylamino)-6,7-dihydroxytetralin)		Studies
(nifedipine)		Trials
(nifedipine)		Recent Studies (post-2010) (nifedipine)
460016,0242,4961,505

Protein Interaction Comparison

ProteinTaxonomy2-(n,n-dimethylamino)-6,7-dihydroxytetralin (IC50)nifedipine (IC50)
perilipin-5Homo sapiens (human)7.133
perilipin-1Homo sapiens (human)9.619
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)8.376
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.0429
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.035
Cytochrome P450 1A2Homo sapiens (human)0.3
Cytochrome P450 3A4Homo sapiens (human)10
Adenosine receptor A3Homo sapiens (human)7.214
Cytochrome P450 2C9 Homo sapiens (human)3.06
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)10
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)7.214
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.0385
Potassium voltage-gated channel subfamily A member 5Homo sapiens (human)6.1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Rattus norvegicus (Norway rat)1.12
Adenosine receptor A1Homo sapiens (human)7.701
3-oxo-5-alpha-steroid 4-dehydrogenase 2Rattus norvegicus (Norway rat)1.12
C-C chemokine receptor type 2Homo sapiens (human)2.191
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)7.214
Cytochrome P450 2J2Homo sapiens (human)3.06
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.4733
Voltage-dependent L-type calcium channel subunit alpha-1CMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.035
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.0394
Myosin light chain kinase, smooth muscleHomo sapiens (human)2.02
Potassium channel subfamily K member 2 Bos taurus (cattle)8.2
Indoleamine 2,3-dioxygenase 2Mus musculus (house mouse)1.5
Voltage-dependent L-type calcium channel subunit alpha-1DMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1FMus musculus (house mouse)1.2

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moulds, RF; Stevens, MJ2
Jenkin, RA; Moulds, RF; Stevens, MJ1

Other Studies

3 other study(ies) available for 2-(n,n-dimethylamino)-6,7-dihydroxytetralin and nifedipine

ArticleYear
Alpha adrenoceptor activation and postreceptor contractile mechanisms in the human digital artery.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:1

    Topics: Calcium; Dose-Response Relationship, Drug; Egtazic Acid; Humans; In Vitro Techniques; Inositol Phosphates; Methoxamine; Nifedipine; Norepinephrine; Receptors, Adrenergic, alpha; Tetrahydronaphthalenes; Vasoconstriction

1990
Human vascular alpha-adrenoceptors: the relevance of subtypes.
    Clinical and experimental pharmacology & physiology, 1987, Volume: 14, Issue:5

    Topics: Animals; Aorta; Arteries; Calcium; Fingers; Guinea Pigs; Humans; In Vitro Techniques; Inositol Phosphates; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Receptors, Adrenergic, alpha; Tetrahydronaphthalenes

1987
Antagonism by nifedipine of alpha-1 and alpha-2 adrenoceptor-mediated responses of human digital arteries.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:3

    Topics: Electric Stimulation; Fingers; Humans; In Vitro Techniques; Methoxamine; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Tetrahydronaphthalenes; Tritium; Vasoconstriction; Yohimbine

1986