2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and triciribine

2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with triciribine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Hu, C; Lee, H; Solomon, VR; Ulibarri, G1
Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A1
Chiu, JF; Fukagawa, NK; Gagne, J; Li, M1
Axanova, LS; Chen, YQ; Cramer, SD; McCoy, T; Sui, G1
Au, LC; Chang, CL; Fai Kwok, C; Ho, LT; Huang, SW; Juan, CC1
Chen, W; Cheng, J; Ji, X; Kong, J; Li, J; Mujahid, H; Wang, H; Yin, Y; Zhai, C; Zhang, Y1
Gao, M; He, D; Shen, J; Zhang, B1
Kang, C; Li, L; Li, Z; Pan, X; Wang, Y; Zhou, Q1

Other Studies

8 other study(ies) available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and triciribine

ArticleYear
The efficacy and selectivity of tumor cell killing by Akt inhibitors are substantially increased by chloroquine.
    Bioorganic & medicinal chemistry, 2008, Sep-01, Volume: 16, Issue:17

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Chloroquine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Molecular Structure; Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinoxalines; Stereoisomerism; Structure-Activity Relationship

2008
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
    The Biochemical journal, 2013, Apr-15, Volume: 451, Issue:2

    Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase

2013
Age-related differences in insulin-like growth factor-1 receptor signaling regulates Akt/FOXO3a and ERK/Fos pathways in vascular smooth muscle cells.
    Journal of cellular physiology, 2008, Volume: 217, Issue:2

    Topics: Age Factors; Aging; Animals; Catalase; Cells, Cultured; Chromones; Crosses, Genetic; Cyclin-Dependent Kinase Inhibitor p27; Extracellular Signal-Regulated MAP Kinases; Forkhead Box Protein O3; Forkhead Transcription Factors; Insulin-Like Growth Factor I; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Proliferating Cell Nuclear Antigen; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred BN; Rats, Inbred F344; Receptor, IGF Type 1; Ribonucleosides; RNA Interference; RNA, Small Interfering; Signal Transduction; Superoxide Dismutase; Transfection; Tyrphostins

2008
1,25-dihydroxyvitamin D(3) and PI3K/AKT inhibitors synergistically inhibit growth and induce senescence in prostate cancer cells.
    The Prostate, 2010, Nov-01, Volume: 70, Issue:15

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Chromones; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Flow Cytometry; Humans; Immunoblotting; Male; Mice; Mice, Knockout; Morpholines; Oxadiazoles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Ribonucleosides; Vitamin D

2010
Insulin up-regulates heme oxygenase-1 expression in 3T3-L1 adipocytes via PI3-kinase- and PKC-dependent pathways and heme oxygenase-1-associated microRNA downregulation.
    Endocrinology, 2011, Volume: 152, Issue:2

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Cells, Cultured; Chromones; Heme Oxygenase-1; Immunoblotting; Indoles; Insulin; Male; Mice; MicroRNAs; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleosides; Signal Transduction

2011
Selective inhibition of PI3K/Akt/mTOR signaling pathway regulates autophagy of macrophage and vulnerability of atherosclerotic plaque.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Animals; Atherosclerosis; Autophagy; Cells, Cultured; Chromones; Cytokines; Lipids; Macrophages, Peritoneal; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Plaque, Atherosclerotic; Proto-Oncogene Proteins c-akt; Rabbits; Ribonucleosides; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2014
Inhaled Methane Protects Rats Against Neurological Dysfunction Induced by Cerebral Ischemia and Reperfusion Injury: PI3K/Akt/HO-1 Pathway Involved.
    Archives of medical research, 2017, Volume: 48, Issue:6

    Topics: Analysis of Variance; Animals; Antioxidants; Biomarkers; Brain Diseases; Brain Ischemia; Chromones; Disease Models, Animal; Enzyme Inhibitors; Heme Oxygenase-1; Male; Malondialdehyde; Methane; Morpholines; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Ribonucleosides; Signal Transduction; Tumor Necrosis Factor-alpha

2017
Assessment of tantalum nanoparticle-induced MC3T3-E1 proliferation and underlying mechanisms.
    Journal of materials science. Materials in medicine, 2021, Oct-23, Volume: 32, Issue:11

    Topics: 3T3 Cells; Animals; Apoptosis; Biocompatible Materials; Cell Proliferation; Chromones; Gene Expression Regulation; Materials Testing; Metal Nanoparticles; Mice; Microtubule-Associated Proteins; Morpholines; Ribonucleosides; Sirolimus; Tantalum

2021