2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with sphingosine in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (18.52) | 18.2507 |
| 2000's | 14 (51.85) | 29.6817 |
| 2010's | 8 (29.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Conway, AM; Pyne, NJ; Pyne, S | 1 |
| Bilney, AJ; Hartfield, PJ; Murray, AW | 1 |
| Bitar, KN; Ibitayo, AI; Nozu, F; Owyang, C; Tsunoda, Y | 1 |
| Downward, J; Watton, SJ | 1 |
| Christensen, RA; de Aos Scherpenseel, I; Fujikawa, K; Jain, SK; Presman, E; Varticovski, L | 1 |
| Cho, S; Dawson, G | 1 |
| Conway, A; Pyne, NJ; Pyne, S | 1 |
| Cho, S; Dawson, G; Dawson, PE | 1 |
| Calcerrada, MC; Catalán, RE; Martín, L; Martínez, AM; Miguel, BG | 1 |
| Chung, JH; Eun, HC; Kim, DS; Kim, KH; Kim, SY; Park, KC | 1 |
| Buckley, A; Chilvers, ER; Haslett, C; MacKinnon, AC; Rossi, AG; Sethi, T | 1 |
| Dawson, G; Dawson, SA; Moskal, JR | 1 |
| Davies, MG; Fegley, AJ; Kim, D; Nicholl, SM; Roztocil, E; Tanski, WJ | 1 |
| Bradford, HN; Colman, RW; Gaughan, JP; Isordia-Salas, I; Katkade, V; Panetti, TS; Soyombo, AA | 1 |
| Hanai, Y; Kato, K; Kozawa, O; Matsushima-Nishiwaki, R; Takai, S; Tokuda, H | 1 |
| Bae, YS; Kim, JM; Kim, MK; Kim, SD; Lee, HY; Lee, SY; Park, KS; Ryu, SH | 1 |
| Chatterjee, S; Kolmakova, A; Pili, R; Rajesh, M; Zang, D | 1 |
| Cattaneo, MG; Lucci, G; Vicentini, LM | 1 |
| Baek, KJ; Jeong, HS; Kim, DS; Kwon, NS; Lee, SH; Park, KC; Yun, HY | 1 |
| Bredow, M; Brünnert, D; Ehrhardt, J; Goyal, P; Piccenini, S; Zygmunt, M | 1 |
| Cheng, R; Hu, T; Pan, HY; Shao, MY; Xu, J; Yang, H; Zhang, P | 1 |
| Han, Z; Li, L; Mai, P; Tian, L; Wang, L; Yang, L; Zhang, Y | 1 |
| Bao, XH; Chen, BD; Li, HX; Li, XM; Ma, YT; Tao, J; Yang, YN | 1 |
| Fang, R; Li, M; Li, W; Wen, K; Zhang, LL; Zhang, LZ | 1 |
| Ji, X; Li, L; Tian, L; Yang, J; Yang, L | 1 |
| Lu, G; Mu, Q; Wang, X; Yang, N; Zhan, E; Zhang, T | 1 |
27 other study(ies) available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and sphingosine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Sphingosine 1-phosphate activation of MAP kinase--involvement of PI 3-kinase and protein kinase C.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromones; Enzyme Activation; Enzyme Inhibitors; Guinea Pigs; Indoles; Lysophospholipids; Maleimides; Morpholines; Muscle, Smooth; Phosphatidylinositol 3-Kinases; Protein Kinase C; Respiratory System; Sphingosine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1997 |
Neurotrophic factors prevent ceramide-induced apoptosis downstream of c-Jun N-terminal kinase activation in PC12 cells.
Topics: Amino Acid Chloromethyl Ketones; Androstadienes; Animals; Apoptosis; Cell Survival; Chromones; Cyclic AMP; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Fibroblast Growth Factor 2; Flavonoids; Hypoglycemic Agents; Insulin; Morpholines; Nerve Growth Factors; Neurons; Neuropeptides; Neuroprotective Agents; PC12 Cells; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-jun; Rats; Sphingosine; Thionucleotides; Wortmannin | 1998 |
Src kinase and PI 3-kinase as a transduction pathway in ceramide-induced contraction of colonic smooth muscle.
Topics: Amino Acid Sequence; Androstadienes; Animals; Benzoquinones; Calcium; Chromones; Colon; Egtazic Acid; Enzyme Inhibitors; In Vitro Techniques; Kinetics; Lactams, Macrocyclic; Models, Biological; Molecular Sequence Data; Morpholines; Muscle Contraction; Muscle, Smooth; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Quinones; Rabbits; Rifabutin; Signal Transduction; Sphingosine; src Homology Domains; Substrate Specificity; Wortmannin | 1998 |
Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction.
Topics: 3T3 Cells; Animals; Binding Sites; Blood Proteins; Cattle; Cell Communication; Cell Line; Chromones; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Extracellular Matrix; Fetal Blood; Fluorescent Antibody Technique; Green Fluorescent Proteins; Insulin; Luminescent Proteins; Mice; Morpholines; Phosphatidylinositols; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Fusion Proteins; Sphingosine | 1999 |
Role of PI 3-kinase in angiopoietin-1-mediated migration and attachment-dependent survival of endothelial cells.
Topics: Angiopoietin-1; Apoptosis; Cell Adhesion; Cell Movement; Cell Survival; Chromones; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Fibroblast Growth Factor 2; Humans; Lymphokines; Membrane Glycoproteins; Mitogen-Activated Protein Kinases; Morpholines; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sphingosine; Umbilical Veins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1999 |
Palmitoyl protein thioesterase 1 protects against apoptosis mediated by Ras-Akt-caspase pathway in neuroblastoma cells.
Topics: Apoptosis; Caspase 3; Caspases; Cell Division; Cell Membrane; Cell Survival; Chromones; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Morpholines; Neuroblastoma; Neurons; Palmitoyl Coenzyme A; Palmitoyl-CoA Hydrolase; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins p21(ras); Sphingosine; Transfection; Tumor Cells, Cultured | 2000 |
Ceramide-dependent regulation of p42/p44 mitogen-activated protein kinase and c-Jun N-terminal-directed protein kinase in cultured airway smooth muscle cells.
Topics: Animals; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Ceramides; Chromones; Enzyme Activation; Guinea Pigs; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Lysophospholipids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Muscle, Smooth; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet-Derived Growth Factor; Precipitin Tests; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; Quinazolines; Respiratory System; Signal Transduction; Sphingosine; Tyrphostins | 2000 |
Role of palmitoyl-protein thioesterase in cell death: implications for infantile neuronal ceroid lipofuscinosis.
Topics: Antibiotics, Antineoplastic; Apoptosis; Chromones; Daunorubicin; Enzyme Inhibitors; Etoposide; Humans; Infant; Morpholines; Nerve Degeneration; Neuroblastoma; Neuronal Ceroid-Lipofuscinoses; Neurons; Nucleic Acid Synthesis Inhibitors; Sphingosine; Staurosporine; Thiolester Hydrolases; Transfection; Tumor Cells, Cultured | 2001 |
Involvement of phosphatidylinositol 3-kinase in nuclear translocation of protein kinase C zeta induced by C2-ceramide in rat hepatocytes.
Topics: Active Transport, Cell Nucleus; Androstadienes; Animals; Cell Membrane; Cell Nucleus; Cell Separation; Chromones; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hepatocytes; Isoenzymes; Male; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Rats; Rats, Wistar; Sphingosine; Subcellular Fractions; Wortmannin | 2002 |
Delayed ERK activation by ceramide reduces melanin synthesis in human melanocytes.
Topics: Adolescent; Cells, Cultured; Chromones; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Kinetics; Lysophospholipids; Melanins; Melanocytes; Microphthalmia-Associated Transcription Factor; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Monophenol Monooxygenase; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrones; Sphingosine; Transcription Factors | 2002 |
Sphingosine kinase: a point of convergence in the action of diverse neutrophil priming agents.
Topics: Adult; Apoptosis; Calcium Signaling; Cell Polarity; Cell Size; Chromones; Enzyme Activation; Enzyme Inhibitors; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Fragments; Phosphoinositide-3 Kinase Inhibitors; Phosphotransferases (Alcohol Group Acceptor); Platelet Activating Factor; Recombinant Proteins; Respiratory Burst; Signal Transduction; Sphingosine; Substance P; Superoxides; Tumor Necrosis Factor-alpha | 2002 |
Transfection of 2,6 and 2,3-sialyltransferase genes and GlcNAc-transferase genes into human glioma cell line U-373 MG affects glycoconjugate expression and enhances cell death.
Topics: Antineoplastic Agents; beta-D-Galactoside alpha 2-6-Sialyltransferase; Caspase 3; Caspases; Cell Death; Cell Line, Tumor; Cell Membrane; Cell Survival; Chromones; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Glioma; Glycoconjugates; Glycosylation; Humans; Morpholines; N-Acetylglucosaminyltransferases; Oligosaccharides; Sialyltransferases; Sphingosine; Staurosporine; Transfection | 2004 |
Sphingosine-1-phosphate-induced smooth muscle cell migration involves the mammalian target of rapamycin.
Topics: Androstadienes; Animals; Blotting, Western; Cell Movement; Cells, Cultured; Chromones; Flavonoids; Lysophospholipids; Morpholines; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Sphingosine; Wortmannin | 2005 |
Domain 5 of cleaved high molecular weight kininogen inhibits endothelial cell migration through Akt.
Topics: Androstadienes; Animals; Cattle; Cell Movement; Cells, Cultured; Chemotaxis; Chromones; Endothelial Cells; Focal Adhesions; Glycogen Synthase Kinase 3; Humans; Kininogen, High-Molecular-Weight; Lysophospholipids; Morpholines; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Structure, Tertiary; Signal Transduction; Sphingosine; Time Factors; Vascular Endothelial Growth Factor A; Wortmannin | 2005 |
Phosphatidylinositol 3-kinase/Akt plays a role in sphingosine 1-phosphate-stimulated HSP27 induction in osteoblasts.
Topics: Androstadienes; Animals; Cell Line; Chromones; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heat-Shock Proteins; Lysophospholipids; Mice; Morpholines; Osteoblasts; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Sphingosine; Time Factors; Wortmannin | 2006 |
S1P stimulates chemotactic migration and invasion in OVCAR3 ovarian cancer cells.
Topics: Blotting, Western; Calcium; Cell Line, Tumor; Cell Movement; Chemotaxis; Chromones; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Lysophospholipids; Morpholines; Neoplasm Invasiveness; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphoinositide-3 Kinase Inhibitors; Protein Isoforms; Proto-Oncogene Proteins c-akt; Pyridines; Receptors, Lysosphingolipid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sphingosine | 2007 |
VEGF recruits lactosylceramide to induce endothelial cell adhesion molecule expression and angiogenesis in vitro and in vivo.
Topics: Animals; Antigens, CD; Blotting, Western; Cell Line; Cell Line, Tumor; Chromones; Endothelial Cells; Female; Fibroblast Growth Factor 2; Galactosyltransferases; Glucosyltransferases; Humans; Lactosylceramides; Mice; Mice, Nude; Morpholines; Neovascularization, Physiologic; Phosphoinositide-3 Kinase Inhibitors; Phosphotransferases (Alcohol Group Acceptor); Platelet Endothelial Cell Adhesion Molecule-1; Receptors, Lysosphingolipid; Sphingosine; Suramin; Vascular Endothelial Growth Factor A | 2009 |
Oxytocin stimulates in vitro angiogenesis via a Pyk-2/Src-dependent mechanism.
Topics: Cell Movement; Cells, Cultured; Chromones; Endothelial Cells; Enzyme Inhibitors; Estrenes; Focal Adhesion Kinase 2; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Morpholines; Neovascularization, Physiologic; Oxytocin; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrrolidinones; Receptors, Oxytocin; RNA, Small Interfering; Signal Transduction; Sphingosine; src-Family Kinases; Type C Phospholipases; Umbilical Veins; Vascular Endothelial Growth Factor A | 2009 |
Involvement of mTOR signaling in sphingosylphosphorylcholine-induced hypopigmentation effects.
Topics: Analysis of Variance; Animals; Blotting, Western; Cell Line; Chromones; Dose-Response Relationship, Drug; Hypopigmentation; Luciferases; Melanins; Mice; Microscopy, Phase-Contrast; Monophenol Monooxygenase; Morpholines; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; Sphingosine; TOR Serine-Threonine Kinases; Transfection | 2011 |
Cytokine IL-6 secretion by trophoblasts regulated via sphingosine-1-phosphate receptor 2 involving Rho/Rho-kinase and Rac1 signaling pathways.
Topics: Amides; Aminoquinolines; Cell Line; Chromones; Cycloheximide; Dactinomycin; Female; Humans; Interleukin-6; Lysophospholipids; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Pregnancy; Pyrazoles; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; Receptors, Lysosphingolipid; rho GTP-Binding Proteins; rho-Associated Kinases; RNA Interference; RNA, Small Interfering; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; Trophoblasts | 2013 |
Sphingosine-1-phosphate mediates AKT/ERK maintenance of dental pulp homoeostasis.
Topics: Adolescent; Adult; Amides; Apoptosis; Blotting, Western; Butadienes; Cell Culture Techniques; Cell Proliferation; Chromones; Dental Pulp; Homeostasis; Humans; In Vitro Techniques; Lysophospholipids; Membrane Potential, Mitochondrial; Molar, Third; Morpholines; Nitriles; Pyridines; Signal Transduction; Sphingosine | 2015 |
Sphingosine 1-Phosphate Receptor 2 and 3 Mediate Bone Marrow-Derived Monocyte/Macrophage Motility in Cholestatic Liver Injury in Mice.
Topics: Animals; Bone Marrow Cells; Cell Movement; Cells, Cultured; Chemokines; Chromones; Cytokines; Enzyme-Linked Immunosorbent Assay; Fatty Liver; Fibrosis; Liver; Lysophospholipids; Macrophages; Mice; Mice, Inbred ICR; Mice, Transgenic; Microscopy, Fluorescence; Morpholines; Neuropeptides; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyrazoles; Pyridines; rac1 GTP-Binding Protein; Real-Time Polymerase Chain Reaction; Receptors, Lysosphingolipid; RNA Interference; RNA, Small Interfering; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors | 2015 |
[Role and related mechanism of S1P/S1P1 signal pathway during post conditioning of hypertrophic cardiomyocytes].
Topics: Animals; Apoptosis; Caspase 3; Cells, Cultured; Chromones; Ischemic Postconditioning; Lysophospholipids; MAP Kinase Signaling System; Morpholines; Myocytes, Cardiac; Norepinephrine; Rats; Receptors, Lysosphingolipid; Sphingosine; Sphingosine-1-Phosphate Receptors | 2016 |
Sphingosine 1-Phosphate Postconditioning Protects Against Myocardial Ischemia/reperfusion Injury in Rats via Mitochondrial Signaling and Akt-Gsk3β Phosphorylation.
Topics: Animals; Chromones; Cytochromes c; Glycogen Synthase Kinase 3 beta; Ischemic Postconditioning; Lysophospholipids; Male; Membrane Potential, Mitochondrial; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Morpholines; Myocardial Infarction; Myocardial Reperfusion Injury; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-akt; Rats, Wistar; Signal Transduction; Sphingosine | 2017 |
Sphingosine 1-Phosphate (S1P)/S1P Receptor2/3 Axis Promotes Inflammatory M1 Polarization of Bone Marrow-Derived Monocyte/Macrophage via G(α)i/o/PI3K/JNK Pathway.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Arginase; Cell Movement; Chemokines; Chromones; Cytokines; GTP-Binding Protein alpha Subunits, Gi-Go; JNK Mitogen-Activated Protein Kinases; Lysophospholipids; Macrophages; Mice; Mice, Inbred ICR; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pyrazoles; Pyridines; Receptors, Cell Surface; Receptors, Lysosphingolipid; RNA Interference; RNA, Small Interfering; Signal Transduction; Sphingosine | 2018 |
Sphingosine-1-Phosphate Improves the Biological Features of Mouse Bone Marrow-Derived EPCs Partially through PI3K/AKT/eNOS/NO Pathway.
Topics: Animals; Cell Adhesion; Cell Survival; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Endothelial Progenitor Cells; Gene Expression Regulation; Lysophospholipids; Mice; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Sphingosine | 2019 |