2-(4-morpholinyl)-4h-1-benzopyran-4-one and nu 7441

2-(4-morpholinyl)-4h-1-benzopyran-4-one has been researched along with nu 7441 in 2 studies

Compound Research Comparison

Studies (2-(4-morpholinyl)-4h-1-benzopyran-4-one)	Trials (2-(4-morpholinyl)-4h-1-benzopyran-4-one)	Recent Studies (post-2010) (2-(4-morpholinyl)-4h-1-benzopyran-4-one)	Studies (nu 7441)	Trials (nu 7441)	Recent Studies (post-2010) (nu 7441)
6	0	0	93	0	82

Protein Interaction Comparison

Protein	Taxonomy	nu 7441 (IC50)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)	0.03
Bromodomain-containing protein 4	Homo sapiens (human)	1
Neuronal acetylcholine receptor subunit alpha-4	Rattus norvegicus (Norway rat)	0.03
Neuronal acetylcholine receptor subunit beta-2	Rattus norvegicus (Norway rat)	0.03
Type-1 angiotensin II receptor	Oryctolagus cuniculus (rabbit)	0.13
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)	1.7533
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)	0.016
Serine/threonine-protein kinase mTOR	Homo sapiens (human)	2.05
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)	0.22
DNA-dependent protein kinase catalytic subunit	Homo sapiens (human)	0.0242
Mu-type opioid receptor	Cavia porcellus (domestic guinea pig)	0.03
Bromodomain testis-specific protein	Homo sapiens (human)	3.5

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Golding, BT; Griffin, RJ; Hardcastle, IR; Leahy, JJ; Richardson, C; Rigoreau, L; Smith, GC	1
Bardos, J; Cano, C; Golding, BT; Griffin, RJ; Hardcastle, IR; Parveen, N; Payne, SL; Peacock, M; Rodriguez-Aristegui, S	1

Other Studies

2 other study(ies) available for 2-(4-morpholinyl)-4h-1-benzopyran-4-one and nu 7441

Article	Year
Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries. Bioorganic & medicinal chemistry letters, 2004, Dec-20, Volume: 14, Issue:24 Topics: Chromones; DNA-Activated Protein Kinase; DNA-Binding Proteins; Enzyme Inhibitors; Molecular Structure; Morpholines; Protein Serine-Threonine Kinases; Structure-Activity Relationship	2004
Mapping the ATP-binding domain of DNA-dependent protein kinase (DNA-PK) with coumarin- and isocoumarin-derived inhibitors. Bioorganic & medicinal chemistry letters, 2010, Jun-15, Volume: 20, Issue:12 Topics: Adenosine Triphosphate; Antineoplastic Agents; Binding Sites; Chromones; Coumarins; DNA-Activated Protein Kinase; Humans; Inhibitory Concentration 50; Isocoumarins; Structure-Activity Relationship	2010

Article

Year

Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries.

Bioorganic & medicinal chemistry letters, 2004, Dec-20, Volume: 14, Issue:24

Topics: Chromones; DNA-Activated Protein Kinase; DNA-Binding Proteins; Enzyme Inhibitors; Molecular Structure; Morpholines; Protein Serine-Threonine Kinases; Structure-Activity Relationship

2004

Mapping the ATP-binding domain of DNA-dependent protein kinase (DNA-PK) with coumarin- and isocoumarin-derived inhibitors.

Bioorganic & medicinal chemistry letters, 2010, Jun-15, Volume: 20, Issue:12

Topics: Adenosine Triphosphate; Antineoplastic Agents; Binding Sites; Chromones; Coumarins; DNA-Activated Protein Kinase; Humans; Inhibitory Concentration 50; Isocoumarins; Structure-Activity Relationship

2010