2-(4-morpholinoanilino)-6-cyclohexylaminopurine has been researched along with vx680 in 1 studies
| Studies (2-(4-morpholinoanilino)-6-cyclohexylaminopurine) | Trials (2-(4-morpholinoanilino)-6-cyclohexylaminopurine) | Recent Studies (post-2010) (2-(4-morpholinoanilino)-6-cyclohexylaminopurine) | Studies (vx680) | Trials (vx680) | Recent Studies (post-2010) (vx680) |
|---|---|---|---|---|---|
| 85 | 0 | 62 | 227 | 3 | 143 |
| Protein | Taxonomy | 2-(4-morpholinoanilino)-6-cyclohexylaminopurine (IC50) | vx680 (IC50) |
|---|---|---|---|
| Aurora kinase A | Homo sapiens (human) | 0.1805 | |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | 0.4538 | |
| Tyrosine-protein kinase ABL1 | Mus musculus (house mouse) | 5 | |
| Proto-oncogene tyrosine-protein kinase Src | Gallus gallus (chicken) | 0.34 | |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | 0.4432 | |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | 0.5 | |
| Beta-1 adrenergic receptor | Homo sapiens (human) | 0.055 | |
| Breakpoint cluster region protein | Homo sapiens (human) | 0.0501 | |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | 0.0006 | |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | 0.0092 | |
| G1/S-specific cyclin-D1 | Homo sapiens (human) | 0.0006 | |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | 0.4974 | |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | 0.03 | |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | 0.4974 | |
| Aurora kinase A | Mus musculus (house mouse) | 0.0006 | |
| Receptor-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | 0.208 | |
| Maternal embryonic leucine zipper kinase | Homo sapiens (human) | 0.42 | |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | 0.1295 | |
| Receptor-interacting serine/threonine-protein kinase 1 | Mus musculus (house mouse) | 1 | |
| Aurora kinase B-A | Xenopus laevis (African clawed frog) | 0.019 | |
| Aurora kinase B | Homo sapiens (human) | 0.2175 | |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | 3.1131 | |
| Aurora kinase C | Homo sapiens (human) | 0.3516 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, SW; Hao, SY; Li, WB; Qiao, XP; Wang, ZX; Xu, Y; Zhang, XJ | 1 |
1 other study(ies) available for 2-(4-morpholinoanilino)-6-cyclohexylaminopurine and vx680
| Article | Year |
|---|---|
Discovery of novel 2,4-disubstituted pyrimidines as Aurora kinase inhibitors.
Topics: Apoptosis; Aurora Kinase A; Aurora Kinase B; bcl-2-Associated X Protein; Binding Sites; Cell Line, Tumor; Drug Design; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Pyrimidines; Structure-Activity Relationship | 2020 |