Page last updated: 2024-09-05

2-(4-morpholinoanilino)-6-cyclohexylaminopurine and nocodazole

2-(4-morpholinoanilino)-6-cyclohexylaminopurine has been researched along with nocodazole in 4 studies

Compound Research Comparison

Studies
(2-(4-morpholinoanilino)-6-cyclohexylaminopurine)
Trials
(2-(4-morpholinoanilino)-6-cyclohexylaminopurine)
Recent Studies (post-2010)
(2-(4-morpholinoanilino)-6-cyclohexylaminopurine)
Studies
(nocodazole)
Trials
(nocodazole)
Recent Studies (post-2010) (nocodazole)
850623,0780655

Protein Interaction Comparison

ProteinTaxonomy2-(4-morpholinoanilino)-6-cyclohexylaminopurine (IC50)nocodazole (IC50)
Chain A, Glutathione-requiring prostaglandin D synthaseHomo sapiens (human)65
nuclear receptor subfamily 0 group B member 1Homo sapiens (human)0.8334
Tyrosine-protein kinase ABL1Homo sapiens (human)0.64
Tubulin alpha-1A chainSus scrofa (pig)1.3775
Tubulin beta chainSus scrofa (pig)0.76
Tubulin beta-4A chainHomo sapiens (human)1.2975
Tubulin beta chainHomo sapiens (human)1.2975
Tubulin alpha-3C chainHomo sapiens (human)1.2975
Adenosine receptor A2aHomo sapiens (human)7.509
Tubulin alpha-1B chainHomo sapiens (human)1.2975
Tubulin alpha-4A chainHomo sapiens (human)1.2975
Tubulin beta-4B chainHomo sapiens (human)1.2975
Sodium-dependent dopamine transporter Homo sapiens (human)6.232
Tubulin beta-3 chainHomo sapiens (human)1.2975
Tubulin beta-2A chainHomo sapiens (human)1.2975
Tubulin beta-8 chainHomo sapiens (human)1.2975
Tubulin beta-2B chainBos taurus (cattle)2.3
Tubulin alpha-3E chainHomo sapiens (human)1.2975
Tubulin alpha-1A chainHomo sapiens (human)1.2975
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)2.3
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)2.3
Tubulin alpha-1C chainHomo sapiens (human)1.2975
Tubulin beta-6 chainHomo sapiens (human)1.2975
Tubulin beta-2B chainHomo sapiens (human)1.2975
Tubulin beta-1 chainHomo sapiens (human)1.2975

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brakenhoff, RH; de Lange, J; de Menezes, RX; de Winter, JP; Faramarz, A; King, RW; Oostra, AB; Rockx, DA; Rooimans, MA; van Beusechem, VW; van der Meulen, IH; Wolthuis, RMF1
Abrieu, A; Castedo, M; Chibon, F; JemaĆ , M; Kroemer, G; Lissa, D; Lledo, G; Manic, G; Morin, N; Reynes, C; Sistigu, A; Vitale, I1
Choudhary, C; Larsen, MS; Narita, T; Nilsson, J; Schou, J; Wild, T1
Benezra, R; Chin, Y; Khoo, C; Marks, DH; Shah, R; Thomas, R1

Other Studies

4 other study(ies) available for 2-(4-morpholinoanilino)-6-cyclohexylaminopurine and nocodazole

ArticleYear
Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function.
    Nature communications, 2015, Oct-01, Volume: 6

    Topics: Anaphase-Promoting Complex-Cyclosome; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line; Chromosome Segregation; Humans; Mitosis; Morpholines; Nocodazole; Paclitaxel; Protein Kinase Inhibitors; Purines; RNA, Small Interfering; Sister Chromatid Exchange; Tubulin Modulators

2015
Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition.
    Oncotarget, 2016, Jan-05, Volume: 7, Issue:1

    Topics: Apoptosis; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Diploidy; HCT116 Cells; Humans; Immunoblotting; M Phase Cell Cycle Checkpoints; Microscopy, Fluorescence; Mitosis; Morpholines; Neoplasms; Nocodazole; Paclitaxel; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Purines; RNA Interference; Tetraploidy; Time-Lapse Imaging; Tubulin Modulators

2016
The Spindle Assembly Checkpoint Is Not Essential for Viability of Human Cells with Genetically Lowered APC/C Activity.
    Cell reports, 2016, Mar-01, Volume: 14, Issue:8

    Topics: Anaphase; Anaphase-Promoting Complex-Cyclosome; Cell Cycle Proteins; Cell Survival; CRISPR-Cas Systems; Gene Deletion; Gene Expression; HCT116 Cells; Humans; M Phase Cell Cycle Checkpoints; Mad2 Proteins; Metaphase; Morpholines; Nocodazole; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Purines; Signal Transduction; Spindle Apparatus; Ubiquitin-Conjugating Enzymes

2016
Mad2 Overexpression Uncovers a Critical Role for TRIP13 in Mitotic Exit.
    Cell reports, 2017, 05-30, Volume: 19, Issue:9

    Topics: Animals; ATPases Associated with Diverse Cellular Activities; Base Sequence; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Proliferation; Gene Knockdown Techniques; Gene Knockout Techniques; Humans; Mad2 Proteins; Mice; Mitosis; Morpholines; Neoplasms; Nocodazole; Phenotype; Purines; Xenograft Model Antitumor Assays

2017