2-(4-ethoxybenzyl)-1-diethylaminoethyl-5-isothiocyanatobenzimidazole and u-50488

2-(4-ethoxybenzyl)-1-diethylaminoethyl-5-isothiocyanatobenzimidazole has been researched along with u-50488 in 1 studies

Compound Research Comparison

Studies (2-(4-ethoxybenzyl)-1-diethylaminoethyl-5-isothiocyanatobenzimidazole)	Trials (2-(4-ethoxybenzyl)-1-diethylaminoethyl-5-isothiocyanatobenzimidazole)	Recent Studies (post-2010) (2-(4-ethoxybenzyl)-1-diethylaminoethyl-5-isothiocyanatobenzimidazole)	Studies (u-50488)	Trials (u-50488)	Recent Studies (post-2010) (u-50488)
14	0	2	1,664	3	209

Protein Interaction Comparison

Protein	Taxonomy	u-50488 (IC50)
Delta-type opioid receptor	Rattus norvegicus (Norway rat)	2.15
Kappa-type opioid receptor	Mus musculus (house mouse)	0.0027
Mu-type opioid receptor	Rattus norvegicus (Norway rat)	2.15
Kappa-type opioid receptor	Rattus norvegicus (Norway rat)	0.7171
Kappa-type opioid receptor	Cavia porcellus (domestic guinea pig)	0.0958
Kappa-type opioid receptor	Homo sapiens (human)	0.0537

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Mash, DC; Partilla, J; Rice, KC; Rothman, RB; Staley, JK	1

Other Studies

1 other study(ies) available for 2-(4-ethoxybenzyl)-1-diethylaminoethyl-5-isothiocyanatobenzimidazole and u-50488

Article	Year
Kappa2 opioid receptors in limbic areas of the human brain are upregulated by cocaine in fatal overdose victims. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Nov-01, Volume: 17, Issue:21 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adult; Amygdala; Benzeneacetamides; Benzomorphans; Binding, Competitive; Brain; Brain Chemistry; Caudate Nucleus; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Drug Overdose; Female; Fentanyl; Gyrus Cinguli; Humans; Isothiocyanates; Kinetics; Male; Morphinans; Protein Binding; Pyrrolidines; Receptors, Opioid, kappa; Tissue Distribution; Up-Regulation	1997

Article

Year

Kappa2 opioid receptors in limbic areas of the human brain are upregulated by cocaine in fatal overdose victims.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Nov-01, Volume: 17, Issue:21

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adult; Amygdala; Benzeneacetamides; Benzomorphans; Binding, Competitive; Brain; Brain Chemistry; Caudate Nucleus; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Drug Overdose; Female; Fentanyl; Gyrus Cinguli; Humans; Isothiocyanates; Kinetics; Male; Morphinans; Protein Binding; Pyrrolidines; Receptors, Opioid, kappa; Tissue Distribution; Up-Regulation

1997