2-(4-ethoxybenzyl)-1-diethylaminoethyl-5-isothiocyanatobenzimidazole has been researched along with fentanyl in 7 studies
| Studies (2-(4-ethoxybenzyl)-1-diethylaminoethyl-5-isothiocyanatobenzimidazole) | Trials (2-(4-ethoxybenzyl)-1-diethylaminoethyl-5-isothiocyanatobenzimidazole) | Recent Studies (post-2010) (2-(4-ethoxybenzyl)-1-diethylaminoethyl-5-isothiocyanatobenzimidazole) | Studies (fentanyl) | Trials (fentanyl) | Recent Studies (post-2010) (fentanyl) |
|---|---|---|---|---|---|
| 14 | 0 | 2 | 15,288 | 4,310 | 4,483 |
| Protein | Taxonomy | 2-(4-ethoxybenzyl)-1-diethylaminoethyl-5-isothiocyanatobenzimidazole (IC50) | fentanyl (IC50) |
|---|---|---|---|
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 6.5 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.6342 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0122 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.1888 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0122 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.0058 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.3092 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 5.893 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 1.58 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0031 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 1.8197 | |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | 4.973 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.354 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blalock, JE; Bost, KL; Carr, DJ; DeCosta, BR; Jacobson, AE; Kim, CH; Rice, KC | 1 |
| Chuang, DM; Coscia, CJ; McLean, S; Rice, KC; Roth, BL; Rothman, RB; Spain, JW | 1 |
| Aceto, MD; Bajwa, BS; Harris, LS; Jacobson, AE; Klee, WA; Lessor, RA; May, EL; Rice, KC; Smith, CB; Streaty, RA | 1 |
| Bowen, WD; Burke, TR; Bykov, V; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB; Schumacher, UK | 1 |
| Burke, TR; Danks, JA; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB | 2 |
| Mash, DC; Partilla, J; Rice, KC; Rothman, RB; Staley, JK | 1 |
7 other study(ies) available for 2-(4-ethoxybenzyl)-1-diethylaminoethyl-5-isothiocyanatobenzimidazole and fentanyl
| Article | Year |
|---|---|
Anti-opioid receptor antibody recognition of a binding site on brain and leukocyte opioid receptors.
Topics: Animals; Antibodies, Monoclonal; Brain; Chromatography, Affinity; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Fentanyl; Immunochemistry; Indicators and Reagents; Isothiocyanates; Leukocytes; Membranes; Mice; Mice, Inbred C57BL; Receptors, Opioid; Thiocyanates; Tritium | 1990 |
Cross-linking of [125I]beta-endorphin to mu-opioid receptors during development.
Topics: Alkylation; Animals; Autoradiography; beta-Endorphin; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Female; Fentanyl; Isothiocyanates; Male; Microsomes; Rats; Receptors, Opioid; Receptors, Opioid, mu; Succinimides; Synaptic Membranes; Thiocyanates | 1989 |
Probes for narcotic receptor mediated phenomena. 13. Potential irreversible narcotic antagonist-based ligands derived from 6,14-endo-ethenotetrahydronororipavine with 7-(methoxyfumaroyl)amino, (bromoacetyl)amino, or isothiocyanate electrophiles: chemistry
Topics: Animals; Brain; Enkephalin, Leucine; Fentanyl; In Vitro Techniques; Isothiocyanates; Ligands; Male; Mice; Mice, Inbred ICR; Narcotic Antagonists; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship; Thebaine; Thiocyanates | 1986 |
Preparation of rat brain membranes greatly enriched with either type-I-delta or type-II-delta opiate binding sites using site directed alkylating agents: evidence for a two-site allosteric model.
Topics: Alkylating Agents; Allosteric Regulation; Animals; Brain; Cell Membrane; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Isothiocyanates; Kinetics; Male; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Thiocyanates | 1984 |
Ionic conditions differentially affect 3H-DADL binding to type-I and type-II opiate delta receptors in vitro.
Topics: Animals; Brain; Calcium; Cell Membrane; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Isothiocyanates; Kinetics; Manganese; Osmolar Concentration; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Sodium; Thiocyanates | 1984 |
Tritiated-6-beta-fluoro-6-desoxy-oxymorphone: a highly selective ligand for the opiate mu receptor whose binding is characterized by low nonspecific binding.
Topics: Animals; Benzomorphans; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Hydromorphone; Isothiocyanates; Kinetics; Oxymorphone; Rats; Receptors, Opioid; Receptors, Opioid, mu; Thiocyanates; Tomography, Emission-Computed | 1984 |
Kappa2 opioid receptors in limbic areas of the human brain are upregulated by cocaine in fatal overdose victims.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adult; Amygdala; Benzeneacetamides; Benzomorphans; Binding, Competitive; Brain; Brain Chemistry; Caudate Nucleus; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Drug Overdose; Female; Fentanyl; Gyrus Cinguli; Humans; Isothiocyanates; Kinetics; Male; Morphinans; Protein Binding; Pyrrolidines; Receptors, Opioid, kappa; Tissue Distribution; Up-Regulation | 1997 |