Compounds > 2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one
Page last updated: 2024-09-02

2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one and naloxone

2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one has been researched along with naloxone in 1 studies

Compound Research Comparison

Studies
(2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one)		Trials
(2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one)		Recent Studies (post-2010)
(2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one)		Studies
(naloxone)		Trials
(naloxone)		Recent Studies (post-2010) (naloxone)
560220,1341,2573,321

Protein Interaction Comparison

ProteinTaxonomy2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one (IC50)naloxone (IC50)
Cytochrome P450 2D6Homo sapiens (human)2
Delta-type opioid receptorMus musculus (house mouse)0.043
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0219
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0019
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0019
Mu-type opioid receptorHomo sapiens (human)0.0397
Delta-type opioid receptorHomo sapiens (human)0.1896
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.05
Kappa-type opioid receptorHomo sapiens (human)0.0795
Mu-type opioid receptorMus musculus (house mouse)0.0154
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.0089
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.0055

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bianchi, M; Fumagalli, P; Mantegazza, P; Panerai, AE; Rovati, LC; Sacerdote, P1

Other Studies

1 other study(ies) available for 2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one and naloxone

ArticleYear
Benzodiazepines and their antagonists interfere with opioid-dependent stress-induced analgesia.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:1

    Topics: Analgesia; Animals; Benzodiazepines; Drug Interactions; Electroshock; Flumazenil; In Vitro Techniques; Male; Mesencephalon; Naloxone; Pain; Pyrazoles; Rats; Rats, Inbred Strains; Sensory Thresholds; Stress, Physiological

1990