2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one and glycine

2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one has been researched along with glycine in 2 studies

Compound Research Comparison

Studies (2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one)	Trials (2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one)	Recent Studies (post-2010) (2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one)	Studies (glycine)	Trials (glycine)	Recent Studies (post-2010) (glycine)
56	0	2	35,163	756	8,415

Protein Interaction Comparison

Protein	Taxonomy	glycine (IC50)
Glutamate receptor ionotropic, NMDA 1	Rattus norvegicus (Norway rat)	1.4852
Sodium- and chloride-dependent glycine transporter 1	Homo sapiens (human)	106
Glutamate receptor ionotropic, NMDA 2A	Rattus norvegicus (Norway rat)	0.3253
Glutamate receptor ionotropic, NMDA 2B	Rattus norvegicus (Norway rat)	0.3253
Glutamate receptor ionotropic, NMDA 2C	Rattus norvegicus (Norway rat)	0.3253
Glutamate receptor ionotropic, NMDA 2D	Rattus norvegicus (Norway rat)	0.3253
Glutamate receptor ionotropic, NMDA 3B	Rattus norvegicus (Norway rat)	0.3253
Glutamate receptor ionotropic, NMDA 3A	Rattus norvegicus (Norway rat)	0.3253
Sodium- and chloride-dependent glycine transporter 2	Homo sapiens (human)	128

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
De Deyn, PP; Macdonald, RL; Marescau, B	1
De Deyn, PP; Macdonald, RL	1

Other Studies

2 other study(ies) available for 2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one and glycine

Article	Year
Guanidino compounds that are increased in hyperargininemia inhibit GABA and glycine responses on mouse neurons in cell culture. Epilepsy research, 1991, Volume: 8, Issue:2 Topics: Animals; Arginine; Cells, Cultured; Electrophysiology; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Guanidines; Homoarginine; Mice; Neurons; Pregnancy; Pyrazoles; Spinal Cord	1991
Guanidino compounds that are increased in cerebrospinal fluid and brain of uremic patients inhibit GABA and glycine responses on mouse neurons in cell culture. Annals of neurology, 1990, Volume: 28, Issue:5 Topics: Animals; Brain Chemistry; Cells, Cultured; Creatinine; Drug Synergism; GABA Antagonists; Glycine; Guanidine; Guanidines; Methylguanidine; Mice; Neurons; Pyrazoles; Spinal Cord; Succinates; Uremia	1990

Article

Year

Guanidino compounds that are increased in hyperargininemia inhibit GABA and glycine responses on mouse neurons in cell culture.

Epilepsy research, 1991, Volume: 8, Issue:2

Topics: Animals; Arginine; Cells, Cultured; Electrophysiology; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Guanidines; Homoarginine; Mice; Neurons; Pregnancy; Pyrazoles; Spinal Cord

1991

Guanidino compounds that are increased in cerebrospinal fluid and brain of uremic patients inhibit GABA and glycine responses on mouse neurons in cell culture.

Annals of neurology, 1990, Volume: 28, Issue:5

Topics: Animals; Brain Chemistry; Cells, Cultured; Creatinine; Drug Synergism; GABA Antagonists; Glycine; Guanidine; Guanidines; Methylguanidine; Mice; Neurons; Pyrazoles; Spinal Cord; Succinates; Uremia

1990