2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one has been researched along with diazepam in 18 studies
| Studies (2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one) | Trials (2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one) | Recent Studies (post-2010) (2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one) | Studies (diazepam) | Trials (diazepam) | Recent Studies (post-2010) (diazepam) |
|---|---|---|---|---|---|
| 56 | 0 | 2 | 18,377 | 2,329 | 1,790 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (83.33) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bernasconi, R; Leonhardt, T; Martin, P; Portet, C; Schmutz, M; Steulet, AF | 1 |
| Galecka, E; Gidynska, T; Raszewski, W; Rump, S | 1 |
| Randall, JI; Rodgers, RJ | 1 |
| Joly, D; Sanger, DJ | 1 |
| Bennett, DA | 2 |
| De Deyn, PP; Macdonald, RL | 2 |
| Bennett, DA; Bernard, PS; Liebman, JM; Pastor, G; Yokoyama, N | 1 |
| Shannon, HE; Thompson, WA | 1 |
| Meiners, BA; Salama, AI | 1 |
| Bernasconi, R; Klebs, K; Klein, M; Maitre, L; Marescaux, C; Martin, P; Portet, C; Schmutz, M; Vergnes, M | 1 |
| Boast, CA; Gerhardt, SC | 1 |
| Brown, C; Jones, B; Martin, I; Oakley, N | 1 |
| Brown, CL; Martin, IL | 1 |
| Bernard, P; Cassidy, JP; Czernik, AJ; Petrack, B; Yokoyama, N | 1 |
| Herling, S; Shannon, HE | 1 |
| Blaney, FE; Edge, C; Phippen, RW | 1 |
1 review(s) available for 2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one and diazepam
| Article | Year |
|---|---|
Pharmacology of the pyrazolo-type compounds: agonist, antagonist and inverse agonist actions.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Diazepam; Hypnotics and Sedatives; Muscle Relaxants, Central; Pyrazoles; Rats; Receptors, GABA-A | 1987 |
17 other study(ies) available for 2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one and diazepam
| Article | Year |
|---|---|
Effects of benzodiazepine receptor ligands with different intrinsic activities on seizures induced by inhibition of GAD.
Topics: Animals; Anti-Anxiety Agents; Carbolines; Diazepam; Flumazenil; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Isoniazid; Male; Mice; Mice, Inbred Strains; Pyrazoles; Reaction Time; Receptors, GABA-A; Seizures | 1992 |
Effects of CGS 9896 in acute experimental intoxication with fluostigmine.
Topics: Animals; Atropine; Diazepam; Female; Isoflurophate; Lethal Dose 50; Mice; Obidoxime Chloride; Pyrazoles | 1990 |
Are the analgesic effects of social defeat mediated by benzodiazepine receptors?
Topics: Analgesia; Animals; Behavior, Animal; Carbolines; Diazepam; Flumazenil; Male; Mice; Mice, Inbred DBA; Pyrazoles; Receptors, GABA-A; Social Behavior | 1987 |
Anxiolytic drugs and the acquisition of conditioned fear in mice.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Chlordiazepoxide; Conditioning, Psychological; Diazepam; Fear; Male; Mice; Motor Activity; Piperazines; Pyrazoles | 1985 |
The non-sedating anxiolytic CGS 9896 produces discriminative stimuli that may be related to an anxioselective effect.
Topics: Animals; Anti-Anxiety Agents; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Meprobamate; Pyrazoles; Pyridazines; Rats; Rats, Inbred Strains | 1985 |
Effects of non-sedative anxiolytic drugs on responses to GABA and on diazepam-induced enhancement of these responses on mouse neurones in cell culture.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Buspirone; Carbolines; Cells, Cultured; Convulsants; Diazepam; Electrophysiology; Flumazenil; gamma-Aminobutyric Acid; Mice; Neurons; Pyrazoles; Quinolines; Spinal Cord | 1988 |
CGS 9896: agonist-antagonist benzodiazepine receptor activity revealed by anxiolytic, anticonvulsant and muscle relaxation assessment in rodents.
Topics: Acoustic Stimulation; Aggression; Agonistic Behavior; Animals; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Electroshock; Male; Motor Activity; Muscle Contraction; Muscle Relaxation; Pentylenetetrazole; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures | 1985 |
Pyrazoloquinoline benzodiazepine receptor ligands: effects on schedule-controlled behavior in dogs.
Topics: Animals; Conditioning, Operant; Convulsants; Diazepam; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Ligands; Male; Pyrazoles; Receptors, GABA-A; Reinforcement Schedule | 1985 |
Enhancement of GABA binding by the benzodiazepine partial agonist CGS9896.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Calcium Chloride; Diazepam; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; Pyrazoles; Pyridazines; Rats; Receptors, GABA-A | 1985 |
CGS 9896 and ZK 91296, but not CGS 8216 and RO 15-1788, are pure benzodiazepine receptor antagonists on mouse neurons in culture.
Topics: Animals; Brain; Carbolines; Cells, Cultured; Diazepam; Electrophysiology; Flumazenil; gamma-Aminobutyric Acid; Mice; Neurons; Pyrazoles; Receptors, GABA-A; Spinal Cord | 1987 |
Evaluation of the anticonvulsant and biochemical activity of CGS 8216 and CGS 9896 in animal models.
Topics: Animals; Anticonvulsants; Brain; Diazepam; Electric Stimulation; Epilepsy; gamma-Aminobutyric Acid; Male; Pyrazoles; Rats; Rats, Inbred Strains | 1988 |
Lack of tolerance or withdrawal effects in mice after chronic administration of the non-sedating anxiolytic, CGS 9896.
Topics: Animals; Diazepam; Drug Tolerance; Male; Mice; Mice, Inbred Strains; Motor Activity; Pyrazoles; Reflex; Seizures; Substance Withdrawal Syndrome | 1987 |
In vivo determination of efficacy of pyrazoloquinolinones at the benzodiazepine receptor.
Topics: Animals; Binding, Competitive; Brain; Convulsants; Diazepam; Flunitrazepam; Male; Mice; Pentylenetetrazole; Pyrazoles; Receptors, GABA-A | 1984 |
Modification of pyrazoloquinolinone affinity by GABA predicts efficacy at the benzodiazepine receptor.
Topics: Animals; Diazepam; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kinetics; Male; Membranes; Mice; Mice, Inbred Strains; Pentylenetetrazole; Pyrazoles; Radioligand Assay; Receptors, GABA-A; Seizures | 1984 |
Benzodiazepine receptor ligands with opposing pharmacologic actions.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Diazepam; Flumazenil; Flunitrazepam; Kinetics; Ligands; Membranes; Models, Psychological; Pyrazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A; Temperature | 1983 |
Antagonism of the discriminative effects of diazepam by pyrazoloquinolines in rats.
Topics: Animals; Diazepam; Discrimination Learning; Male; Pyrazoles; Rats; Rats, Inbred F344; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Molecular surface comparison. 2. Similarity of electrostatic vector fields in drug design.
Topics: Anti-Anxiety Agents; Benzamides; Benzazepines; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Diazepam; Drug Design; Electricity; GABA-A Receptor Agonists; Granisetron; Indoles; Isomerism; Molecular Conformation; Ondansetron; Pharmaceutical Preparations; Protein Binding; Pyrazoles; Pyridazines; Receptors, Drug; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Structure-Activity Relationship; Surface Properties; Triazolam; Tropisetron | 1995 |