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2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one and chlordiazepoxide

2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one has been researched along with chlordiazepoxide in 7 studies

Compound Research Comparison

Studies
(2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one)
Trials
(2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one)
Recent Studies (post-2010)
(2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one)
Studies
(chlordiazepoxide)
Trials
(chlordiazepoxide)
Recent Studies (post-2010) (chlordiazepoxide)
56023,962385104

Protein Interaction Comparison

ProteinTaxonomy2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one (IC50)chlordiazepoxide (IC50)
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.216
Gamma-aminobutyric acid receptor subunit alpha-1Bos taurus (cattle)0.9967
Gamma-aminobutyric acid receptor subunit beta-1Bos taurus (cattle)0.9967
Gamma-aminobutyric acid receptor subunit alpha-2Bos taurus (cattle)0.9967
Gamma-aminobutyric acid receptor subunit alpha-3Bos taurus (cattle)0.9967
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.216
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.216
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.216
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)1.1
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.216
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.216
Gamma-aminobutyric acid receptor subunit alpha-4Bos taurus (cattle)0.9967
Gamma-aminobutyric acid receptor subunit gamma-2Bos taurus (cattle)0.9967
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.216
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.216
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.216
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.216
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.216
Histamine H1 receptorHomo sapiens (human)1.795
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.216
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.216
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.216
GABA theta subunitRattus norvegicus (Norway rat)0.216
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.216

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Galizio, M; Journey, JW; Royal, SA; Welker, JA1
Karim, KH; Najim, RA1
Leidenheimer, NJ; Schechter, MD1
Joly, D; Sanger, DJ; Zivkovic, B1
Joly, D; Sanger, DJ1
Ambrose, F; Barbaz, B; Bittiger, H; Iyengar, S; Neale, RF; Petrack, B; Rinehart, RK; Steel, DJ; Williams, M; Wood, PL1
Sanger, DJ; Zivkovic, B1

Other Studies

7 other study(ies) available for 2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one and chlordiazepoxide

ArticleYear
Variable-interval schedules of timeout from avoidance: effects of anxiolytic and antipsychotic drugs in rats.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Buspirone; Chlordiazepoxide; Chlorpromazine; Conditioning, Operant; Male; Pyrazoles; Rats; Rats, Inbred Strains; Reinforcement Schedule

1990
Effect of CGS 9896 on stress-induced gastric ulcer in rat.
    Clinical and experimental pharmacology & physiology, 1990, Volume: 17, Issue:2

    Topics: Animals; Benzodiazepines; Chlordiazepoxide; Cold Temperature; Drug Therapy, Combination; Flumazenil; Hyperglycemia; Male; Pyrazoles; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Physiological

1990
Discriminative stimulus properties of CGS 9896: interactions within the GABA/benzodiazepine receptor complex.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:2

    Topics: Animals; Carbolines; Chlordiazepoxide; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Male; Pentobarbital; Pentylenetetrazole; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A

1988
Behavioral effects of nonbenzodiazepine anxiolytic drugs: a comparison of CGS 9896 and zopiclone with chlordiazepoxide.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Behavior, Animal; Chlordiazepoxide; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Drinking Behavior; Feeding Behavior; Male; Piperazines; Punishment; Pyrazoles; Rats; Rats, Inbred Strains; Reinforcement Schedule; Reinforcement, Psychology

1985
Anxiolytic drugs and the acquisition of conditioned fear in mice.
    Psychopharmacology, 1985, Volume: 85, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Chlordiazepoxide; Conditioning, Psychological; Diazepam; Fear; Male; Mice; Motor Activity; Piperazines; Pyrazoles

1985
Benzodiazepine interactions with central thyroid-releasing hormone binding sites: characterization and physiological significance.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:1

    Topics: Amygdala; Animals; Benzodiazepines; Brain; Cerebral Cortex; Chlordiazepoxide; Corpus Striatum; Cyclic GMP; Flunitrazepam; Kinetics; Male; Membranes; Midazolam; Pentobarbital; Pyrazoles; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Thyrotropin-Releasing Hormone; Sleep; Thiazolidines; Thyrotropin; Thyrotropin-Releasing Hormone

1986
Discriminative stimulus properties of chlordiazepoxide and zolpidem. Agonist and antagonist effects of CGS 9896 and ZK 91296.
    Neuropharmacology, 1987, Volume: 26, Issue:5

    Topics: Animals; Brain; Carbolines; Chlordiazepoxide; Discrimination Learning; Drug Interactions; Generalization, Psychological; Male; Pyrazoles; Pyridines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Zolpidem

1987