Compounds > 2-(4-amidinophenyl)-1-benzofuran-5-carboxamidine
Page last updated: 2024-09-04

2-(4-amidinophenyl)-1-benzofuran-5-carboxamidine and pentamidine

2-(4-amidinophenyl)-1-benzofuran-5-carboxamidine has been researched along with pentamidine in 2 studies

Compound Research Comparison

Studies
(2-(4-amidinophenyl)-1-benzofuran-5-carboxamidine)		Trials
(2-(4-amidinophenyl)-1-benzofuran-5-carboxamidine)		Recent Studies (post-2010)
(2-(4-amidinophenyl)-1-benzofuran-5-carboxamidine)		Studies
(pentamidine)		Trials
(pentamidine)		Recent Studies (post-2010) (pentamidine)
5002,411136477

Protein Interaction Comparison

ProteinTaxonomy2-(4-amidinophenyl)-1-benzofuran-5-carboxamidine (IC50)pentamidine (IC50)
Solute carrier family 22 member 2Homo sapiens (human)1.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)3.278
Protein tyrosine phosphatase type IVA 3Homo sapiens (human)0.3
Solute carrier family 22 member 3Homo sapiens (human)9.5
PlasminogenHomo sapiens (human)7.3333
Urokinase-type plasminogen activatorHomo sapiens (human)10
Trypsin-1Homo sapiens (human)10
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)2.214
Muscarinic acetylcholine receptor M2Homo sapiens (human)1.425
Muscarinic acetylcholine receptor M4Homo sapiens (human)1.58
Muscarinic acetylcholine receptor M5Homo sapiens (human)2.885
Alpha-2A adrenergic receptorHomo sapiens (human)1.375
Cytochrome P450 2D6Homo sapiens (human)10
Amine oxidase [flavin-containing] AHomo sapiens (human)0.793
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.214
5-hydroxytryptamine receptor 2AHomo sapiens (human)1.639
5-hydroxytryptamine receptor 2CHomo sapiens (human)3.278
D(3) dopamine receptorHomo sapiens (human)3.998
Sodium-dependent dopamine transporter Homo sapiens (human)3.159
Glutamate receptor ionotropic, NMDA 1Homo sapiens (human)0.72
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)10
Glutamate receptor ionotropic, NMDA 2AHomo sapiens (human)0.72
Protein tyrosine phosphatase type IVA 2Homo sapiens (human)0.3
Multidrug and toxin extrusion protein 2Homo sapiens (human)2.7
Protein tyrosine phosphatase type IVA 1Homo sapiens (human)0.3
Multidrug and toxin extrusion protein 1Homo sapiens (human)1.7033

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Clercq, ED; Dann, O1
Bakunov, SA; Bakunova, SM; Barszcz, T; Brun, R; Tidwell, RR; Wenzler, T; Werbovetz, KA1

Other Studies

2 other study(ies) available for 2-(4-amidinophenyl)-1-benzofuran-5-carboxamidine and pentamidine

ArticleYear
Diaryl amidine derivatives as oncornaviral DNA polymerase inhibitors.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:7

    Topics: Amidines; Animals; Antineoplastic Agents; Kinetics; Leukemia, Experimental; Mice; Moloney murine leukemia virus; Retroviridae; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Tilorone

1980
Synthesis and antiprotozoal activity of cationic 2-phenylbenzofurans.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Animals; Antiprotozoal Agents; Benzofurans; Cations; Disease Models, Animal; Leishmania; Mice; Molecular Structure; Structure-Activity Relationship; Trypanosoma; Trypanosomiasis

2008