Compounds > 2-(4--(methylamino)phenyl)-6-hydroxybenzothiazole

2-(4--(methylamino)phenyl)-6-hydroxybenzothiazole and 12-crown-4

2-(4--(methylamino)phenyl)-6-hydroxybenzothiazole has been researched along with 12-crown-4* in 1 studies

Other Studies

1 other study(ies) available for 2-(4--(methylamino)phenyl)-6-hydroxybenzothiazole and 12-crown-4

Article	Year
Crown ethers attenuate aggregation of amyloid beta of Alzheimer's disease. Chemical communications (Cambridge, England), 2014, Dec-25, Volume: 50, Issue:99 In this report, we reasoned that non-covalent modification of amyloid beta (Aβ) by crown ethers could inhibit its aggregation. We demonstrated that PiB-C, a conjugate PiB and crown ether, could significantly reduce the aggregation in vitro. Additionally, two-photon imaging showed that PiB-C could efficiently label Aβ plaques and CAAs in AD mice. Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Animals; Crown Ethers; Hippocampus; Ligands; Mice; Microscopy, Confocal; Peptide Fragments; Thiazoles	2014

Article

Year

Crown ethers attenuate aggregation of amyloid beta of Alzheimer's disease.

Chemical communications (Cambridge, England), 2014, Dec-25, Volume: 50, Issue:99

In this report, we reasoned that non-covalent modification of amyloid beta (Aβ) by crown ethers could inhibit its aggregation. We demonstrated that PiB-C, a conjugate PiB and crown ether, could significantly reduce the aggregation in vitro. Additionally, two-photon imaging showed that PiB-C could efficiently label Aβ plaques and CAAs in AD mice.

Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Animals; Crown Ethers; Hippocampus; Ligands; Mice; Microscopy, Confocal; Peptide Fragments; Thiazoles

2014