Compounds > 2-(3,4-dichlorophenyl)-n-methyl-n-(1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl)acetamide
Page last updated: 2024-09-03

2-(3,4-dichlorophenyl)-n-methyl-n-(1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl)acetamide and naloxone

2-(3,4-dichlorophenyl)-n-methyl-n-(1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl)acetamide has been researched along with naloxone in 1 studies

Compound Research Comparison

Studies
(2-(3,4-dichlorophenyl)-n-methyl-n-(1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl)acetamide)		Trials
(2-(3,4-dichlorophenyl)-n-methyl-n-(1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl)acetamide)		Recent Studies (post-2010)
(2-(3,4-dichlorophenyl)-n-methyl-n-(1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl)acetamide)		Studies
(naloxone)		Trials
(naloxone)		Recent Studies (post-2010) (naloxone)
80220,1341,2573,321

Protein Interaction Comparison

ProteinTaxonomy2-(3,4-dichlorophenyl)-n-methyl-n-(1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl)acetamide (IC50)naloxone (IC50)
Cytochrome P450 2D6Homo sapiens (human)2
Delta-type opioid receptorMus musculus (house mouse)0.043
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0219
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0019
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0019
Mu-type opioid receptorHomo sapiens (human)0.0397
Delta-type opioid receptorHomo sapiens (human)0.1896
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.05
Kappa-type opioid receptorHomo sapiens (human)0.0795
Mu-type opioid receptorMus musculus (house mouse)0.0154
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.0089
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.0055

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kuzmin, A; Ogren, SO; Sandin, J; Terenius, L1

Other Studies

1 other study(ies) available for 2-(3,4-dichlorophenyl)-n-methyl-n-(1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl)acetamide and naloxone

ArticleYear
Dose- and time-dependent bimodal effects of kappa-opioid agonists on locomotor activity in mice.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetamides; Animals; Benzomorphans; Dose-Response Relationship, Drug; Isothiocyanates; Male; Mice; Morphine; Motor Activity; Naloxone; Naltrexone; Receptors, Opioid, kappa; Time Factors

2000