Compounds > 2-(2-hydroxy-4-methylphenyl)aminothiazole
Page last updated: 2024-09-05

2-(2-hydroxy-4-methylphenyl)aminothiazole and indomethacin

2-(2-hydroxy-4-methylphenyl)aminothiazole has been researched along with indomethacin in 3 studies

Compound Research Comparison

Studies
(2-(2-hydroxy-4-methylphenyl)aminothiazole)		Trials
(2-(2-hydroxy-4-methylphenyl)aminothiazole)		Recent Studies (post-2010)
(2-(2-hydroxy-4-methylphenyl)aminothiazole)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
71029,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomy2-(2-hydroxy-4-methylphenyl)aminothiazole (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bonne, C; Meynier, F; Muller, A1
Bonne, C; Coquelet, C; Latour, E; Tissié, G; Trong, HN1
Bodin, C; Bonne, C; Chastel, C; Colin, J; Jouppe, B; Malet, F1

Other Studies

3 other study(ies) available for 2-(2-hydroxy-4-methylphenyl)aminothiazole and indomethacin

ArticleYear
PAF-induced conjunctivitis in the rabbit is mediated by peptido-leukotrienes.
    Journal of ocular pharmacology, 1990,Fall, Volume: 6, Issue:3

    Topics: Animals; Azepines; Conjunctiva; Conjunctivitis; Cyclooxygenase Inhibitors; Dicarboxylic Acids; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Indomethacin; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Rabbits; Second Messenger Systems; Tetrazoles; Thiazoles; Thienopyridines; Triazoles

1990
Free radical scavenging capacity and anti-inflammatory activity of CBS-113 A.
    Advances in experimental medicine and biology, 1990, Volume: 264

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Free Radical Scavengers; Free Radicals; In Vitro Techniques; Indomethacin; Iron; Liposomes; Male; Oxygen Consumption; Peroxides; Phosphatidylcholines; Rabbits; Superoxides; Thiazoles; Uveitis; Xanthine Oxidase

1990
[Experimental herpes simplex keratitis in rabbits. Evaluation of pro-infectious effects of topical non-steroidal anti-inflammatory agents].
    Journal francais d'ophtalmologie, 1989, Volume: 12, Issue:4

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Evaluation; Flurbiprofen; Indomethacin; Infections; Keratitis, Dendritic; Rabbits; Thiazoles; Time Factors

1989