2-(2,3-dicarboxycyclopropyl)glycine has been researched along with quisqualic acid in 10 studies
| Studies (2-(2,3-dicarboxycyclopropyl)glycine) | Trials (2-(2,3-dicarboxycyclopropyl)glycine) | Recent Studies (post-2010) (2-(2,3-dicarboxycyclopropyl)glycine) | Studies (quisqualic acid) | Trials (quisqualic acid) | Recent Studies (post-2010) (quisqualic acid) |
|---|---|---|---|---|---|
| 14 | 0 | 1 | 1,362 | 0 | 36 |
| 166 | 0 | 27 | 1,362 | 0 | 36 |
| Protein | Taxonomy | 2-(2,3-dicarboxycyclopropyl)glycine (IC50) | quisqualic acid (IC50) |
|---|---|---|---|
| Chain A, Glutamate Receptor 2 | Rattus norvegicus (Norway rat) | 0.02 | |
| Chain A, Glutamate Receptor 2 | Rattus norvegicus (Norway rat) | 0.02 | |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 5.1 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 5.1 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 5.1 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 5.1 | |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | 0.15 | |
| Glutamate receptor 1 | Mus musculus (house mouse) | 0.08 | |
| Glutamate receptor 2 | Mus musculus (house mouse) | 0.08 | |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | 0.15 | |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | 0.15 | |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | 0.15 | |
| Glutamate carboxypeptidase 2 | Homo sapiens (human) | 9.5 | |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | 0.15 | |
| Cystine/glutamate transporter | Homo sapiens (human) | 5 | |
| Glutamate receptor 4 | Mus musculus (house mouse) | 0.08 | |
| Glutamate receptor 3 | Mus musculus (house mouse) | 0.08 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Allgeier, H; Knöpfel, T; Kuhn, R | 1 |
| Acher, FC; Brabet, I; Jullian, N; Pin, JP | 1 |
| Adam, G; Bleuel, Z; Chaboz, S; Ellis, GJ; Faull, RL; Malherbe, P; Messer, J; Metzler, V; Mutel, V; Nilly, A; Richards, JG; Roughley, BS; Schlaeger, EJ | 1 |
| Acher, FC; Bertrand, HO; Bessis, AS; Pin, JP | 1 |
| Casabona, G; Genazzani, AA; L'Episcopo, MR; Nicoletti, F; Shinozaki, H | 2 |
| Choi, S; Lovinger, DM | 1 |
| Alger, BE; Kirov, SA; Morishita, W | 1 |
| Oja, SS; Saransaari, P | 1 |
| Casabona, G; Copani, A; Di Giorgi Gerevini, V; Mutel, V; Nicoletti, F; Nicosia, A; Romano, C; Storto, M | 1 |
1 review(s) available for 2-(2,3-dicarboxycyclopropyl)glycine and quisqualic acid
| Article | Year |
|---|---|
Metabotropic glutamate receptors: novel targets for drug development.
Topics: Animals; Cloning, Molecular; Drug Design; Humans; Receptors, Metabotropic Glutamate | 1995 |
9 other study(ies) available for 2-(2,3-dicarboxycyclopropyl)glycine and quisqualic acid
| Article | Year |
|---|---|
Agonist selectivity of mGluR1 and mGluR2 metabotropic receptors: a different environment but similar recognition of an extended glutamate conformation.
Topics: Animals; Binding Sites; Cell Line; CHO Cells; Cricetinae; Glutamates; Ligands; Models, Molecular; Molecular Conformation; Receptors, Metabotropic Glutamate; Structure-Activity Relationship | 1999 |
Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections.
Topics: Animals; Binding, Competitive; Brain; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Humans; Imidazoles; Indans; Intracellular Fluid; Kainic Acid; Male; Organ Specificity; Quinazolines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recombinant Proteins; Spinal Cord; Transfection | 2000 |
Common and selective molecular determinants involved in metabotopic glutamate receptor agonist activity.
Topics: Binding Sites; Crystallography, X-Ray; Excitatory Amino Acid Agonists; Glutamic Acid; Ligands; Models, Molecular; Receptors, Metabotropic Glutamate; Sequence Homology, Amino Acid; Structure-Activity Relationship | 2002 |
(2s,1'R,2'R,3'R)-2-(2,3-Dicarboxycyclopropyl) glycine enhances quisqualate-stimulated inositol phospholipid hydrolysis in hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Cycloleucine; Cyclopropanes; Glycine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1993 |
(2S,1'R,2'R,3'R)-2-(2,3-dicarboxycyclopropyl) glycine positively modulates metabotropic glutamate receptors coupled to polyphosphoinositide hydrolysis in rat hippocampal slices.
Topics: Animals; Cyclopropanes; Glycine; Hippocampus; Hydrolysis; In Vitro Techniques; Phosphatidylinositol Phosphates; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Stimulation, Chemical | 1994 |
Metabotropic glutamate receptor modulation of voltage-gated Ca2+ channels involves multiple receptor subtypes in cortical neurons.
Topics: Animals; Benzoates; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Cycloleucine; Cyclopropanes; Electrophysiology; Ethylmaleimide; Excitatory Amino Acid Agonists; Glycine; Ion Channel Gating; Neurons; Neurotoxins; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spider Venoms | 1996 |
Evidence for metabotropic glutamate receptor activation in the induction of depolarization-induced suppression of inhibition in hippocampal CA1.
Topics: 4-Aminopyridine; Amino Acids, Dicarboxylic; Animals; Benzoates; Calcium Channels; Cycloleucine; Cyclopropanes; Enzyme Inhibitors; Ethylmaleimide; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Male; Membrane Potentials; Neural Inhibition; Neuroprotective Agents; Patch-Clamp Techniques; Pyramidal Cells; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Signal Transduction; Synapses | 1998 |
Involvement of metabotropic glutamate receptors in taurine release in the adult and developing mouse hippocampus.
Topics: Age Factors; Animals; Cyclopropanes; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Mice; Quisqualic Acid; Receptors, Metabotropic Glutamate; Taurine; Time Factors | 1999 |
Reducing conditions differentially affect the functional and structural properties of group-I and -II metabotropic glutamate receptors.
Topics: Amino Acids, Dicarboxylic; Animals; Anticonvulsants; Carbachol; Cell Membrane; Cerebellum; CHO Cells; Cholinergic Agonists; Colforsin; Cricetinae; Cyclic AMP; Cycloleucine; Cyclopropanes; Dimerization; Dithiothreitol; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Humans; Kidney; Neurons; Neuroprotective Agents; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Signal Transduction | 2000 |