Compounds > 2-(2,3-dicarboxycyclopropyl)glycine
Page last updated: 2024-09-03

2-(2,3-dicarboxycyclopropyl)glycine and ly 379268

2-(2,3-dicarboxycyclopropyl)glycine has been researched along with ly 379268 in 7 studies

Compound Research Comparison

Studies
(2-(2,3-dicarboxycyclopropyl)glycine)		Trials
(2-(2,3-dicarboxycyclopropyl)glycine)		Recent Studies (post-2010)
(2-(2,3-dicarboxycyclopropyl)glycine)		Studies
(ly 379268)		Trials
(ly 379268)		Recent Studies (post-2010) (ly 379268)
14012210116
1660272210116

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (71.43)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Blanco-Urgoiti, J; Collado, I; Espinosa, JF; Johnson, BG; Kingston, AE; Mazón, A; Pedregal, C; Schoepp, DD; Wright, RA1
O'Neill, MJ1
Clinckers, R; Ebinger, G; Lindekens, H; Lodge, D; Meurs, A; Michotte, Y; O'Neill, MJ; Smolders, I1
Alexander, GM; Godwin, DW1
Hsu, KS; Huang, CC1
Broad, LM; Colvin, EM; Findlay, JD; Grubisha, O; Hanna, L; Heinz, BA; Lodge, D; Monn, JA; Sanger, H; Sher, E; Ursu, D; Vivier, RG1
Afsari, HS; Liauw, BW; Vafabakhsh, R1

Other Studies

7 other study(ies) available for 2-(2,3-dicarboxycyclopropyl)glycine and ly 379268

ArticleYear
(2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-methylcyclopropyl) glycine is a potent and selective metabotropic group 2 receptor agonist with anxiolytic properties.
    Journal of medicinal chemistry, 2002, Aug-15, Volume: 45, Issue:17

    Topics: Animals; Anti-Anxiety Agents; Bridged Bicyclo Compounds; Cell Line; Cyclopropanes; Glycine; Ligands; Models, Molecular; Rats; Receptors, Metabotropic Glutamate; Reflex, Startle; Stereoisomerism

2002
Pharmacology and neuroprotective actions of mGlu receptor ligands.
    Developmental medicine and child neurology. Supplement, 2001, Volume: 86

    Topics: Amino Acids; Brain; Brain Ischemia; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Glycine; Hippocampus; Humans; Kainic Acid; Ligands; Nerve Degeneration; Neuroprotective Agents; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate

2001
In vivo modulation of extracellular hippocampal glutamate and GABA levels and limbic seizures by group I and II metabotropic glutamate receptor ligands.
    Journal of neurochemistry, 2004, Volume: 88, Issue:5

    Topics: Amino Acids; Animals; Anticonvulsants; Benzoates; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Ligands; Limbic System; Male; Microdialysis; Pilocarpine; Pyridines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Seizures

2004
Presynaptic inhibition of corticothalamic feedback by metabotropic glutamate receptors.
    Journal of neurophysiology, 2005, Volume: 94, Issue:1

    Topics: Amino Acids; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Feedback; Ferrets; Geniculate Bodies; Glycine; In Vitro Techniques; Male; Neural Inhibition; Neural Pathways; Neurons; Presynaptic Terminals; Receptors, Metabotropic Glutamate; Synaptic Transmission; Time Factors; Xanthenes

2005
The role of NMDA receptors in regulating group II metabotropic glutamate receptor-mediated long-term depression in rat medial prefrontal cortex.
    Neuropharmacology, 2008, Volume: 54, Issue:7

    Topics: Amino Acids; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Long-Term Synaptic Depression; Male; N-Methylaspartate; Patch-Clamp Techniques; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Valine

2008
Pharmacological profiling of native group II metabotropic glutamate receptors in primary cortical neuronal cultures using a FLIPR.
    Neuropharmacology, 2013, Volume: 66

    Topics: Allosteric Regulation; Amino Acids; Amino Acids, Dicarboxylic; Animals; Biphenyl Compounds; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Calcium Signaling; Cerebral Cortex; Cyclic AMP; Cyclopropanes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Indans; Ligands; Mice; Mice, Inbred ICR; Mice, Knockout; Mice, Transgenic; Neurons; Optical Imaging; Primary Cell Culture; Proline; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Sulfonamides

2013
Conformational rearrangement during activation of a metabotropic glutamate receptor.
    Nature chemical biology, 2021, Volume: 17, Issue:3

    Topics: Allosteric Regulation; Amino Acids; Binding Sites; Biosensing Techniques; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Fluorescence Resonance Energy Transfer; Gene Expression; Genetic Vectors; Glutamic Acid; Glycine; HEK293 Cells; Humans; Ligands; Models, Molecular; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Receptors, Metabotropic Glutamate; Single Molecule Imaging

2021