Compounds > 2-(2,3-dicarboxycyclopropyl)glycine
Page last updated: 2024-09-03

2-(2,3-dicarboxycyclopropyl)glycine and l-2-(carboxypropyl)glycine

2-(2,3-dicarboxycyclopropyl)glycine has been researched along with l-2-(carboxypropyl)glycine in 11 studies

Compound Research Comparison

Studies
(2-(2,3-dicarboxycyclopropyl)glycine)		Trials
(2-(2,3-dicarboxycyclopropyl)glycine)		Recent Studies (post-2010)
(2-(2,3-dicarboxycyclopropyl)glycine)		Studies
(l-2-(carboxypropyl)glycine)		Trials
(l-2-(carboxypropyl)glycine)		Recent Studies (post-2010) (l-2-(carboxypropyl)glycine)
14012908

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (54.55)18.2507
2000's5 (45.45)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Allgeier, H; Knöpfel, T; Kuhn, R1
Adam, G; Cartmell, J; Chaboz, S; Henningsen, R; Kemp, JA; Klingelschmidt, A; Metzler, V; Monsma, F; Mutel, V; Schaffhauser, H; Wichmann, J1
Acher, F; Bockaert, J; Brabet, I; De Colle, C; Parmentier, ML; Pin, JP1
Faull, RL; Kratzeisen, C; Lundstrom, K; Malherbe, P; Mutel, V; Richards, JG1
Acher, FC; Brabet, I; Jullian, N; Pin, JP1
Arnold, MB; Johnson, BG; Ornstein, PL; Schoepp, DD; Wheeler, WJ; Wright, RA1
Adam, G; Kratzeisen, C; Lundstrom, K; Malherbe, P; Mutel, V; Ohresser, S; Schweitzer, C; Stadler, H; Wichmann, J; Woltering, T1
Adam, G; Bleuel, Z; Chaboz, S; Ellis, GJ; Faull, RL; Malherbe, P; Messer, J; Metzler, V; Mutel, V; Nilly, A; Richards, JG; Roughley, BS; Schlaeger, EJ1
Arnold, MB; Ornstein, PL; Schoepp, DD; Wheeler, WJ; Wright, RA1
Blanco-Urgoiti, J; Collado, I; Espinosa, JF; Johnson, BG; Kingston, AE; Mazón, A; Pedregal, C; Schoepp, DD; Wright, RA1
Blanco-Urgoiti, J; Bueno, AB; Collado, I; González, R; Griffey, KI; Hoard, DW; Johnson, BG; Kingston, AE; Marcos, A; Moher, ED; Pedregal, C; Pérez-Castells, J; Schoepp, DD; Tizzano, JP; Wright, RA1

Reviews

1 review(s) available for 2-(2,3-dicarboxycyclopropyl)glycine and l-2-(carboxypropyl)glycine

ArticleYear
Metabotropic glutamate receptors: novel targets for drug development.
    Journal of medicinal chemistry, 1995, Apr-28, Volume: 38, Issue:9

    Topics: Animals; Cloning, Molecular; Drug Design; Humans; Receptors, Metabotropic Glutamate

1995

Other Studies

10 other study(ies) available for 2-(2,3-dicarboxycyclopropyl)glycine and l-2-(carboxypropyl)glycine

ArticleYear
Characterization of [3H]-(2S,2'R,3'R)-2-(2',3'-dicarboxy-cyclopropyl)glycine ([3H]-DCG IV) binding to metabotropic mGlu2 receptor-transfected cell membranes.
    British journal of pharmacology, 1998, Volume: 123, Issue:3

    Topics: Animals; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclopropanes; Glycine; Guanosine 5'-O-(3-Thiotriphosphate); Protein Binding; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Sulfur Radioisotopes; Transfection; Tritium

1998
Comparative effect of L-CCG-I, DCG-IV and gamma-carboxy-L-glutamate on all cloned metabotropic glutamate receptor subtypes.
    Neuropharmacology, 1998, Volume: 37, Issue:8

    Topics: 1-Carboxyglutamic Acid; Amino Acids, Dicarboxylic; Cell Line; Cloning, Molecular; Cyclopropanes; Excitatory Amino Acid Agonists; Glycine; Humans; Receptors, Metabotropic Glutamate; Structure-Activity Relationship

1998
Cloning and functional expression of alternative spliced variants of the human metabotropic glutamate receptor 8.
    Brain research. Molecular brain research, 1999, Apr-20, Volume: 67, Issue:2

    Topics: Adult; Alternative Splicing; Animals; Blotting, Northern; Blotting, Southern; Brain Chemistry; CHO Cells; Cloning, Molecular; Cricetinae; DNA Probes; DNA, Complementary; Fetus; Gene Expression Regulation, Viral; Humans; In Situ Hybridization; Kidney; Molecular Sequence Data; Propionates; Receptors, Metabotropic Glutamate; RNA, Messenger; Semliki forest virus; Sequence Homology, Amino Acid; Transfection; Tritium

1999
Agonist selectivity of mGluR1 and mGluR2 metabotropic receptors: a different environment but similar recognition of an extended glutamate conformation.
    Journal of medicinal chemistry, 1999, May-06, Volume: 42, Issue:9

    Topics: Animals; Binding Sites; Cell Line; CHO Cells; Cricetinae; Glutamates; Ligands; Models, Molecular; Molecular Conformation; Receptors, Metabotropic Glutamate; Structure-Activity Relationship

1999
[3H]-LY341495 as a novel antagonist radioligand for group II metabotropic glutamate (mGlu) receptors: characterization of binding to membranes of mGlu receptor subtype expressing cells.
    Neuropharmacology, 1999, Volume: 38, Issue:10

    Topics: Amino Acids; Animals; Binding, Competitive; Calcium; Cell Membrane; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Kinetics; Radioligand Assay; Receptors, Metabotropic Glutamate; Recombinant Proteins; Transfection; Tritium; Xanthenes

1999
Characterization of [(3)H]-LY354740 binding to rat mGlu2 and mGlu3 receptors expressed in CHO cells using semliki forest virus vectors.
    Neuropharmacology, 2000, Jul-24, Volume: 39, Issue:10

    Topics: Amino Acids; Animals; Binding, Competitive; Bridged Bicyclo Compounds; Cell Membrane; Chlorides; CHO Cells; Cricetinae; DNA, Recombinant; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; Genetic Vectors; Glutamic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Rats; Receptors, Metabotropic Glutamate; Semliki forest virus; Tritium; Xanthenes; Zinc Compounds

2000
Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections.
    Journal of neurochemistry, 2000, Volume: 75, Issue:6

    Topics: Animals; Binding, Competitive; Brain; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Humans; Imidazoles; Indans; Intracellular Fluid; Kainic Acid; Male; Organ Specificity; Quinazolines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recombinant Proteins; Spinal Cord; Transfection

2000
Binding of [3H](2S,1'S,2'S)-2-(9-xanthylmethyl)-2-(2'-carboxycyclopropyl) glycine ([3H]LY341495) to cell membranes expressing recombinant human group III metabotropic glutamate receptor subtypes.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 362, Issue:6

    Topics: Amino Acids; Binding, Competitive; Cell Membrane; Excitatory Amino Acid Antagonists; Humans; Kinetics; Radioligand Assay; Receptors, Metabotropic Glutamate; Recombinant Proteins; Substrate Specificity; Tritium; Xanthenes

2000
(2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-methylcyclopropyl) glycine is a potent and selective metabotropic group 2 receptor agonist with anxiolytic properties.
    Journal of medicinal chemistry, 2002, Aug-15, Volume: 45, Issue:17

    Topics: Animals; Anti-Anxiety Agents; Bridged Bicyclo Compounds; Cell Line; Cyclopropanes; Glycine; Ligands; Models, Molecular; Rats; Receptors, Metabotropic Glutamate; Reflex, Startle; Stereoisomerism

2002
(2S,1'S,2'R,3'R)-2-(2'-Carboxy-3'-hydroxymethylcyclopropyl) glycine is a highly potent group 2 and 3 metabotropic glutamate receptor agonist with oral activity.
    Journal of medicinal chemistry, 2004, Jan-15, Volume: 47, Issue:2

    Topics: Administration, Oral; Animals; Cerebral Cortex; Cyclic AMP; Fear; Glycine; In Vitro Techniques; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Reflex, Startle; Stereoisomerism; Structure-Activity Relationship

2004