2-(2,3-dicarboxycyclopropyl)glycine has been researched along with glutamic acid in 36 studies
| Studies (2-(2,3-dicarboxycyclopropyl)glycine) | Trials (2-(2,3-dicarboxycyclopropyl)glycine) | Recent Studies (post-2010) (2-(2,3-dicarboxycyclopropyl)glycine) | Studies (glutamic acid) | Trials (glutamic acid) | Recent Studies (post-2010) (glutamic acid) |
|---|---|---|---|---|---|
| 14 | 0 | 1 | 41,757 | 452 | 12,876 |
| 166 | 0 | 27 | 41,757 | 452 | 12,876 |
| Protein | Taxonomy | 2-(2,3-dicarboxycyclopropyl)glycine (IC50) | glutamic acid (IC50) |
|---|---|---|---|
| Chain A, GLUTAMATE RECEPTOR SUBUNIT 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain A, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain B, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | 0.0057 | |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor 1 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 2 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 3 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | 0.38 | |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | 207 | |
| Glutamate receptor 4 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.1533 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (33.33) | 18.2507 |
| 2000's | 17 (47.22) | 29.6817 |
| 2010's | 6 (16.67) | 24.3611 |
| 2020's | 1 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Allgeier, H; Knöpfel, T; Kuhn, R | 1 |
| Acher, F; Bockaert, J; Brabet, I; De Colle, C; Parmentier, ML; Pin, JP | 1 |
| Faull, RL; Kratzeisen, C; Lundstrom, K; Malherbe, P; Mutel, V; Richards, JG | 1 |
| Acher, FC; Brabet, I; Jullian, N; Pin, JP | 1 |
| Arnold, MB; Johnson, BG; Ornstein, PL; Schoepp, DD; Wheeler, WJ; Wright, RA | 1 |
| Adam, G; Bleuel, Z; Chaboz, S; Ellis, GJ; Faull, RL; Malherbe, P; Messer, J; Metzler, V; Mutel, V; Nilly, A; Richards, JG; Roughley, BS; Schlaeger, EJ | 1 |
| Arnold, MB; Ornstein, PL; Schoepp, DD; Wheeler, WJ; Wright, RA | 1 |
| Acher, FC; Bertrand, HO; Bessis, AS; Pin, JP | 1 |
| Blanco-Urgoiti, J; Collado, I; Espinosa, JF; Johnson, BG; Kingston, AE; Mazón, A; Pedregal, C; Schoepp, DD; Wright, RA | 1 |
| Assaf, Z; Bjørn-Yoshimoto, WE; Brodbeck, R; Bunch, L; Erichsen, MN; Gefflaut, T; Goudet, C; Huynh, TH; Nielsen, B; Pin, JP; Sagot, E; Stensbøl, TB; Thomsen, C; Tora, AS | 1 |
| Hayashi, Y; Mizuno, N; Momiyama, A; Nakanishi, S; Ogawa-Meguro, R; Ohishi, H; Shigemoto, R; Takahashi, T | 1 |
| Ballerini, P; Battaglia, G; Caciagli, F; Ciccarelli, R; Di Iorio, P; Giuliani, P; Nicoletti, F; Poli, A | 1 |
| Bischofberger, J; Schild, D | 1 |
| Glitsch, M; Llano, I; Marty, A | 1 |
| Attwell, PJ; Bradford, HF; Croucher, MJ; Jane, DE; Singh Kent, N | 1 |
| Casabona, G; De Paolis, P; Lucchi, R; Nicoletti, F; Notari, S; Poli, A; Storto, M | 1 |
| Aggleton, JP; Bashir, ZI; Bortolotto, ZA; Brown, MW; Cho, K; Collingridge, GL; Conquet, F; McCaffery, B | 1 |
| Crawford, JH; Heavens, R; Martin, DJ; Pollock, J; Scott, RH; Seabrook, GR; Wainwright, A | 1 |
| Cai, Z; Conn, PJ; Hubalek, F; Macek, TA; Murphy, TJ; Pohl, J; Schaffhauser, H | 1 |
| Savić, N; Sciancalepore, M | 1 |
| Abraham, WC; Mellentin, C | 1 |
| Bernardi, G; Bonsi, P; Calabresi, P; Centonze, D; Conquet, F; Gubellini, P; Picconi, B; Pisani, A | 1 |
| Chen, WP; Kirchgessner, AL | 1 |
| Clinckers, R; Ebinger, G; Lindekens, H; Lodge, D; Meurs, A; Michotte, Y; O'Neill, MJ; Smolders, I | 1 |
| Inoue, M; Kawamura, Y; Kudo, Y; Manita, S; Miyakawa, H; Nakamura, T | 1 |
| Glitsch, M | 1 |
| Ding, JH; Hu, G; Wu, JY; Yang, YJ; Yao, HH; Zhang, J; Zhou, F | 1 |
| Mateo, Z; Porter, JT | 1 |
| Chittajallu, R; Gallo, V; Kunze, A; Mangin, JM | 1 |
| Kinouchi, H; Sugita, M; Yoshioka, H | 1 |
| Breustedt, J; Kintscher, M; Miceli, S; Schmitz, D; Wozny, C | 1 |
| Li, DP; Pan, HL; Ye, ZY | 1 |
| Dionísio, JC; Matias, CM; Quinta-Ferreira, ME; Saggau, P | 1 |
| Blaabjerg, M; Bogetofte, H; Dindler, A; Kamand, M; Meyer, M | 1 |
| Baty, D; Blanc, E; Bossi, S; Chames, P; Daniel, H; de Bundel, D; Dupuis, E; El Moustaine, D; Mathieu, M; Mathis, G; McLean, H; Moreno-Delgado, D; Møller, TC; Nevoltris, D; Pin, JP; Rondard, P; Rovira, X; Scholler, P; Trinquet, E; Valjent, E | 1 |
| Afsari, HS; Liauw, BW; Vafabakhsh, R | 1 |
1 review(s) available for 2-(2,3-dicarboxycyclopropyl)glycine and glutamic acid
| Article | Year |
|---|---|
Metabotropic glutamate receptors: novel targets for drug development.
Topics: Animals; Cloning, Molecular; Drug Design; Humans; Receptors, Metabotropic Glutamate | 1995 |
35 other study(ies) available for 2-(2,3-dicarboxycyclopropyl)glycine and glutamic acid
| Article | Year |
|---|---|
Comparative effect of L-CCG-I, DCG-IV and gamma-carboxy-L-glutamate on all cloned metabotropic glutamate receptor subtypes.
Topics: 1-Carboxyglutamic Acid; Amino Acids, Dicarboxylic; Cell Line; Cloning, Molecular; Cyclopropanes; Excitatory Amino Acid Agonists; Glycine; Humans; Receptors, Metabotropic Glutamate; Structure-Activity Relationship | 1998 |
Cloning and functional expression of alternative spliced variants of the human metabotropic glutamate receptor 8.
Topics: Adult; Alternative Splicing; Animals; Blotting, Northern; Blotting, Southern; Brain Chemistry; CHO Cells; Cloning, Molecular; Cricetinae; DNA Probes; DNA, Complementary; Fetus; Gene Expression Regulation, Viral; Humans; In Situ Hybridization; Kidney; Molecular Sequence Data; Propionates; Receptors, Metabotropic Glutamate; RNA, Messenger; Semliki forest virus; Sequence Homology, Amino Acid; Transfection; Tritium | 1999 |
Agonist selectivity of mGluR1 and mGluR2 metabotropic receptors: a different environment but similar recognition of an extended glutamate conformation.
Topics: Animals; Binding Sites; Cell Line; CHO Cells; Cricetinae; Glutamates; Ligands; Models, Molecular; Molecular Conformation; Receptors, Metabotropic Glutamate; Structure-Activity Relationship | 1999 |
[3H]-LY341495 as a novel antagonist radioligand for group II metabotropic glutamate (mGlu) receptors: characterization of binding to membranes of mGlu receptor subtype expressing cells.
Topics: Amino Acids; Animals; Binding, Competitive; Calcium; Cell Membrane; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Kinetics; Radioligand Assay; Receptors, Metabotropic Glutamate; Recombinant Proteins; Transfection; Tritium; Xanthenes | 1999 |
Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections.
Topics: Animals; Binding, Competitive; Brain; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Humans; Imidazoles; Indans; Intracellular Fluid; Kainic Acid; Male; Organ Specificity; Quinazolines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recombinant Proteins; Spinal Cord; Transfection | 2000 |
Binding of [3H](2S,1'S,2'S)-2-(9-xanthylmethyl)-2-(2'-carboxycyclopropyl) glycine ([3H]LY341495) to cell membranes expressing recombinant human group III metabotropic glutamate receptor subtypes.
Topics: Amino Acids; Binding, Competitive; Cell Membrane; Excitatory Amino Acid Antagonists; Humans; Kinetics; Radioligand Assay; Receptors, Metabotropic Glutamate; Recombinant Proteins; Substrate Specificity; Tritium; Xanthenes | 2000 |
Common and selective molecular determinants involved in metabotopic glutamate receptor agonist activity.
Topics: Binding Sites; Crystallography, X-Ray; Excitatory Amino Acid Agonists; Glutamic Acid; Ligands; Models, Molecular; Receptors, Metabotropic Glutamate; Sequence Homology, Amino Acid; Structure-Activity Relationship | 2002 |
(2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-methylcyclopropyl) glycine is a potent and selective metabotropic group 2 receptor agonist with anxiolytic properties.
Topics: Animals; Anti-Anxiety Agents; Bridged Bicyclo Compounds; Cell Line; Cyclopropanes; Glycine; Ligands; Models, Molecular; Rats; Receptors, Metabotropic Glutamate; Reflex, Startle; Stereoisomerism | 2002 |
New 4-Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III.
Topics: Animals; Cells, Cultured; Crystallography, X-Ray; Dose-Response Relationship, Drug; Glutamic Acid; HEK293 Cells; Humans; Models, Molecular; Molecular Structure; Rats; Receptors, Metabotropic Glutamate; Structure-Activity Relationship | 2016 |
Role of a metabotropic glutamate receptor in synaptic modulation in the accessory olfactory bulb.
Topics: Animals; CHO Cells; Cricetinae; Cyclopropanes; Dendrites; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Interneurons; Olfactory Bulb; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1993 |
Interaction between A1 adenosine and class II metabotropic glutamate receptors in the regulation of purine and glutamate release from rat hippocampal slices.
Topics: Adenosine; Animals; Cycloleucine; Cyclopropanes; Excitatory Amino Acids; Glutamic Acid; Glycine; Hippocampus; Male; Neuroprotective Agents; Neurotoxins; Organ Culture Techniques; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Xanthines | 1996 |
Glutamate and N-acetylaspartylglutamate block HVA calcium currents in frog olfactory bulb interneurons via an mGluR2/3-like receptor.
Topics: Animals; Calcium Channel Blockers; Cells, Cultured; Cyclopropanes; Dipeptides; Glutamic Acid; Glycine; Homovanillic Acid; Interneurons; Ion Channel Gating; Olfactory Bulb; Receptors, Metabotropic Glutamate; Synapses; Xenopus | 1996 |
Glutamate as a candidate retrograde messenger at interneurone-Purkinje cell synapses of rat cerebellum.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Benzoates; Colforsin; Cyclopropanes; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Interneurons; Kinetics; Presynaptic Terminals; Purkinje Cells; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Synapses; Synaptic Transmission; Tetrodotoxin | 1996 |
Anticonvulsant and glutamate release-inhibiting properties of the highly potent metabotropic glutamate receptor agonist (2S,2'R, 3'R)-2-(2',3'-dicarboxycyclopropyl)glycine (DCG-IV).
Topics: Amygdala; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Cyclopropanes; Glutamic Acid; Glycine; Kindling, Neurologic; Lamotrigine; Male; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Seizures; Synaptosomes; Triazines | 1998 |
Predominant expression of group-II metabotropic glutamate receptors in the goldfish brain.
Topics: Animals; Brain; Cyclopropanes; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine; Goldfish; Male; Proline; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Tissue Distribution | 1999 |
Synaptic depression induced by pharmacological activation of metabotropic glutamate receptors in the perirhinal cortex in vitro.
Topics: Animals; Cycloleucine; Cyclopropanes; Electric Stimulation; Entorhinal Cortex; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Glycine; Hippocampus; Male; Neocortex; Neuronal Plasticity; Organ Culture Techniques; Propionates; Rats; Rats, Inbred Strains; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Synaptic Transmission; Temporal Lobe | 1999 |
Mobilisation of intracellular Ca2+ by mGluR5 metabotropic glutamate receptor activation in neonatal rat cultured dorsal root ganglia neurones.
Topics: Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Cells, Cultured; Cycloleucine; Cyclopropanes; Dantrolene; Fluorescence; Ganglia, Spinal; Glutamic Acid; Glycine; Indans; Phenylacetates; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ryanodine; Ryanodine Receptor Calcium Release Channel; Stereoisomerism | 2000 |
cAMP-dependent protein kinase inhibits mGluR2 coupling to G-proteins by direct receptor phosphorylation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Amino Acid Sequence; Animals; Anticonvulsants; CHO Cells; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclopropanes; Dentate Gyrus; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoquinolines; Molecular Sequence Data; Mutagenesis; Neurons; Perforant Pathway; Phosphorylation; Protein Binding; Rats; Receptors, Metabotropic Glutamate; Serine; Sulfonamides; Transfection | 2000 |
Electrophysiological characterization of "giant" cells in stratum radiatum of the CA3 hippocampal region.
Topics: 2-Amino-5-phosphonovalerate; 3,3'-Diaminobenzidine; Action Potentials; Animals; Axons; Bicuculline; Calcium; Cesium; Chlorides; Choline; Cyclopropanes; Dendrites; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Immunoenzyme Techniques; Microscopy, Video; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 2001 |
Priming stimulation of group II metabotropic glutamate receptors inhibits the subsequent induction of rat hippocampal long-term depression in vitro.
Topics: Animals; Anticonvulsants; Cyclopropanes; Electric Stimulation; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine; Hippocampus; Long-Term Potentiation; Male; Methoxyhydroxyphenylglycol; Neural Inhibition; Neuronal Plasticity; Neurons; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 2001 |
Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Action Potentials; Animals; Anticonvulsants; Benzoates; Cyclopropanes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Mice; Mice, Knockout; Muscarine; Muscarinic Agonists; N-Methylaspartate; Neostriatum; Neurons; Phenylacetates; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Synaptic Transmission | 2001 |
Activation of group II mGlu receptors inhibits voltage-gated Ca2+ currents in myenteric neurons.
Topics: Animals; Barium; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Cyclopropanes; Electric Conductivity; Glutamic Acid; Glycine; GTP-Binding Proteins; Guinea Pigs; Ion Channel Gating; Male; Myenteric Plexus; Neurons; Nifedipine; omega-Conotoxin GVIA; Pertussis Toxin; Proline; Receptors, Metabotropic Glutamate | 2002 |
In vivo modulation of extracellular hippocampal glutamate and GABA levels and limbic seizures by group I and II metabotropic glutamate receptor ligands.
Topics: Amino Acids; Animals; Anticonvulsants; Benzoates; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Ligands; Limbic System; Male; Microdialysis; Pilocarpine; Pyridines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Seizures | 2004 |
Glutamate release increases during mossy-CA3 LTP but not during Schaffer-CA1 LTP.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Aspartic Acid; Calcium; Colforsin; Coloring Agents; Cyclopropanes; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Long-Term Potentiation; Magnesium; Male; Mossy Fibers, Hippocampal; Neuroglia; Rats; Rats, Sprague-Dawley; Time Factors | 2004 |
Selective inhibition of spontaneous but not Ca2+ -dependent release machinery by presynaptic group II mGluRs in rat cerebellar slices.
Topics: Action Potentials; Animals; Cadmium; Calcium; Calcium Channels; Cerebellum; Colforsin; Cyclopropanes; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Interneurons; N-Methylaspartate; Nickel; Patch-Clamp Techniques; Presynaptic Terminals; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Vesicles | 2006 |
Activation of Group II/III metabotropic glutamate receptors attenuates LPS-induced astroglial neurotoxicity via promoting glutamate uptake.
Topics: Animals; Apoptosis; Astrocytes; Brain; Cells, Cultured; Cyclopropanes; Excitatory Amino Acid Agonists; Glutamic Acid; Glutathione; Glycine; Immunohistochemistry; Lipopolysaccharides; Neurons; Neuroprotective Agents; Phosphoserine; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 2006 |
Group II metabotropic glutamate receptors inhibit glutamate release at thalamocortical synapses in the developing somatosensory cortex.
Topics: Amino Acids; Animals; Anticonvulsants; Cerebral Cortex; Cyclopropanes; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Immunohistochemistry; In Vitro Techniques; Mice; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Somatosensory Cortex; Synapses; Thalamus; Xanthenes | 2007 |
Satellite NG2 progenitor cells share common glutamatergic inputs with associated interneurons in the mouse dentate gyrus.
Topics: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase; Animals; Animals, Newborn; Antigens; Benzothiadiazines; Cyclopropanes; Dentate Gyrus; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Glycine; Green Fluorescent Proteins; In Vitro Techniques; Interneurons; Mice; Mice, Transgenic; Patch-Clamp Techniques; Phosphopyruvate Hydratase; Phosphoric Diester Hydrolases; Picrotoxin; Proteoglycans; Satellite Cells, Perineuronal; Sodium Channel Blockers; Stem Cells; Tetrodotoxin | 2008 |
Neuroprotective effects of group II metabotropic glutamate receptor agonist DCG-IV on hippocampal neurons in transient forebrain ischemia.
Topics: Amino Acids; Animals; Carotid Stenosis; Cerebrovascular Circulation; Cyclopropanes; Extracellular Space; Glutamic Acid; Glycine; Hippocampus; Ischemic Attack, Transient; Male; Microdialysis; Neurons; Neuroprotective Agents; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Xanthenes | 2009 |
Group II metabotropic glutamate receptors depress synaptic transmission onto subicular burst firing neurons.
Topics: Amino Acids; Amino Acids, Dicarboxylic; Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Cyclopropanes; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Hippocampus; Male; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synaptic Transmission; Xanthenes | 2012 |
Regulation of Hypothalamic Presympathetic Neurons and Sympathetic Outflow by Group II Metabotropic Glutamate Receptors in Spontaneously Hypertensive Rats.
Topics: Adaptation, Physiological; Animals; Cyclopropanes; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Hypertension; Male; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Metabotropic Glutamate; Sympathetic Nervous System | 2013 |
Activation of group II metabotropic glutamate receptors blocks zinc release from hippocampal mossy fibers.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Cyclopropanes; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Mossy Fibers, Hippocampal; Presynaptic Terminals; Rats, Wistar; Receptors, Metabotropic Glutamate; Signal Transduction; Statistics, Nonparametric; Synaptic Transmission; Synaptic Vesicles; Zinc | 2014 |
Activation of Group II Metabotropic Glutamate Receptors Increases Proliferation but does not Influence Neuronal Differentiation of a Human Neural Stem Cell Line.
Topics: Amino Acids; Cell Differentiation; Cell Line; Cell Proliferation; Cell Survival; Cyclopropanes; Glutamic Acid; Glycine; Humans; Neural Stem Cells; Neurons; Receptors, Metabotropic Glutamate; Xanthenes | 2018 |
Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation.
Topics: Allosteric Regulation; Animals; Binding Sites; Camelids, New World; Cyclic AMP; Cyclopropanes; Fear; Glutamic Acid; Glycine; HEK293 Cells; Hippocampus; Humans; Inositol Phosphates; Male; Mice; Mice, Inbred C57BL; Models, Molecular; Neurons; Receptors, Metabotropic Glutamate; Receptors, Opioid; Single-Domain Antibodies | 2017 |
Conformational rearrangement during activation of a metabotropic glutamate receptor.
Topics: Allosteric Regulation; Amino Acids; Binding Sites; Biosensing Techniques; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Fluorescence Resonance Energy Transfer; Gene Expression; Genetic Vectors; Glutamic Acid; Glycine; HEK293 Cells; Humans; Ligands; Models, Molecular; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Receptors, Metabotropic Glutamate; Single Molecule Imaging | 2021 |