Page last updated: 2024-09-03

2-(2,3-dicarboxycyclopropyl)glycine and cycloleucine

2-(2,3-dicarboxycyclopropyl)glycine has been researched along with cycloleucine in 26 studies

Compound Research Comparison

Studies
(2-(2,3-dicarboxycyclopropyl)glycine)
Trials
(2-(2,3-dicarboxycyclopropyl)glycine)
Recent Studies (post-2010)
(2-(2,3-dicarboxycyclopropyl)glycine)
Studies
(cycloleucine)
Trials
(cycloleucine)
Recent Studies (post-2010) (cycloleucine)
1660271,238455

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's17 (65.38)18.2507
2000's9 (34.62)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Battaglia, G; Bruno, V; Copani, A; Nicoletti, F; Raffaele, R; Shinozaki, H1
Casabona, G; Genazzani, AA; L'Episcopo, MR; Nicoletti, F; Shinozaki, H1
Ishida, M; Kwak, S; Miyamoto, M; Shinozaki, H1
Hayashi, Y; Higuchi, T; Kaba, H; Nakanishi, S1
Caciagli, F; Casabona, G; Ciccarelli, R; De Bernardis, E; Di Iorio, P; L'Episcopo, MR; Nicoletti, F; Shinozaki, H1
Ishida, M; Saitoh, T; Shinozaki, H1
Ishida, M; Ohfune, Y; Saitoh, T; Shimamoto, K; Shinozaki, H1
Choi, S; Lovinger, DM1
Ballerini, P; Battaglia, G; Caciagli, F; Ciccarelli, R; Di Iorio, P; Giuliani, P; Nicoletti, F; Poli, A1
Kamiya, H; Sawada, S; Yamamoto, C; Yoshino, M1
Coderre, TJ; Fisher, K1
Abbott, A; Lacey, MG; Wigmore, MA1
Maccaferri, G; McBain, CJ; Tóth, K1
Cassidy, EM; O'Connor, JJ; O'Leary, DM1
Alger, BE; Kirov, SA; Morishita, W1
Kalda, A; Zharkovsky, A1
Aggleton, JP; Bashir, ZI; Bortolotto, ZA; Brown, MW; Cho, K; Collingridge, GL; Conquet, F; McCaffery, B1
Hülsmann, S; Oku, Y; Richter, DW; Zhang, W1
Crawford, JH; Heavens, R; Martin, DJ; Pollock, J; Scott, RH; Seabrook, GR; Wainwright, A1
Casabona, G; Copani, A; Di Giorgi Gerevini, V; Mutel, V; Nicoletti, F; Nicosia, A; Romano, C; Storto, M1
Balcar, VJ; FitzGibbon, T; Lawrance, ML; Pliss, L; Shave, E; Stastny, F1
Oja, SS; Saransaari, P1
Meeker, RB1
Maeda, J; Okauchi, T; Semba, J; Suhara, T1
Kanumilli, S; Roberts, PJ1
Dietrich, D; Wostrack, M1

Other Studies

26 other study(ies) available for 2-(2,3-dicarboxycyclopropyl)glycine and cycloleucine

ArticleYear
Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death.
    European journal of pharmacology, 1994, Apr-11, Volume: 256, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Amino Acids, Dicarboxylic; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Cycloleucine; Cyclopropanes; Glycine; Kainic Acid; Mice; N-Methylaspartate; Neurons; Neurotoxins; Phosphatidylinositols; Receptors, Metabotropic Glutamate

1994
(2s,1'R,2'R,3'R)-2-(2,3-Dicarboxycyclopropyl) glycine enhances quisqualate-stimulated inositol phospholipid hydrolysis in hippocampal slices.
    European journal of pharmacology, 1993, May-15, Volume: 245, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Cycloleucine; Cyclopropanes; Glycine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate

1993
Agonists for metabotropic glutamate receptors in the rat delay recovery from halothane anesthesia.
    European journal of pharmacology, 1994, Jul-21, Volume: 260, Issue:1

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Anesthesia; Animals; Cycloleucine; Cyclopropanes; Glycine; Halothane; Injections, Intraventricular; Male; Neurotoxins; Postural Balance; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate

1994
Induction of an olfactory memory by the activation of a metabotropic glutamate receptor.
    Science (New York, N.Y.), 1994, Jul-08, Volume: 265, Issue:5169

    Topics: Animals; Cycloleucine; Cyclopropanes; Estrus; Female; gamma-Aminobutyric Acid; Glycine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Neuronal Plasticity; Olfactory Bulb; Phentolamine; Pheromones; Pregnancy; Pregnancy, Animal; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Sexual Behavior, Animal

1994
Interaction between metabotropic receptors and purinergic transmission in rat hippocampal slices.
    Brain research, 1994, May-09, Volume: 645, Issue:1-2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cycloleucine; Cyclopropanes; Glycine; Hippocampus; In Vitro Techniques; Male; Neurotoxins; Purines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission

1994
A new metabotropic glutamate receptor agonist: developmental change of its sensitivity to receptors in the newborn rat spinal cord.
    Neuroscience letters, 1993, Oct-01, Volume: 160, Issue:2

    Topics: Amino Acids, Dicarboxylic; Animals; Animals, Newborn; Baclofen; Cycloleucine; Cyclopropanes; Dose-Response Relationship, Drug; Glycine; In Vitro Techniques; Neurotoxins; Rats; Rats, Wistar; Receptors, Glutamate; Spinal Cord; Synapses

1993
A novel metabotropic glutamate receptor agonist: marked depression of monosynaptic excitation in the newborn rat isolated spinal cord.
    British journal of pharmacology, 1993, Volume: 109, Issue:4

    Topics: Amino Acids; Amino Acids, Dicarboxylic; Animals; Animals, Newborn; Cycloleucine; Cyclopropanes; Electric Stimulation; Electrophysiology; Glycine; In Vitro Techniques; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurotoxins; Rats; Rats, Wistar; Receptors, Glutamate; Reflex, Monosynaptic; Spinal Cord

1993
Metabotropic glutamate receptor modulation of voltage-gated Ca2+ channels involves multiple receptor subtypes in cortical neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Volume: 16, Issue:1

    Topics: Animals; Benzoates; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Cycloleucine; Cyclopropanes; Electrophysiology; Ethylmaleimide; Excitatory Amino Acid Agonists; Glycine; Ion Channel Gating; Neurons; Neurotoxins; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spider Venoms

1996
Interaction between A1 adenosine and class II metabotropic glutamate receptors in the regulation of purine and glutamate release from rat hippocampal slices.
    Journal of neurochemistry, 1996, Volume: 67, Issue:1

    Topics: Adenosine; Animals; Cycloleucine; Cyclopropanes; Excitatory Amino Acids; Glutamic Acid; Glycine; Hippocampus; Male; Neuroprotective Agents; Neurotoxins; Organ Culture Techniques; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Xanthines

1996
A metabotropic glutamate receptor agonist DCG-IV suppresses synaptic transmission at mossy fiber pathway of the guinea pig hippocampus.
    Neuroscience letters, 1996, Mar-22, Volume: 207, Issue:1

    Topics: Aminobutyrates; Animals; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agonists; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; Receptors, Metabotropic Glutamate

1996
The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception.
    Pain, 1996, Volume: 68, Issue:2-3

    Topics: Aminobutyrates; Analysis of Variance; Animals; Benzoates; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Formaldehyde; Glycine; Male; Pain; Rats; Receptors, Metabotropic Glutamate; Resorcinols

1996
Excitation of rat subthalamic nucleus neurones in vitro by activation of a group I metabotropic glutamate receptor.
    Brain research, 1997, Aug-22, Volume: 766, Issue:1-2

    Topics: Adenine Nucleotides; Affinity Labels; Animals; Benzoates; Cycloleucine; Cyclopropanes; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Male; Neurons; Neuroprotective Agents; Pyridoxal; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Thalamic Nuclei

1997
Target-specific expression of presynaptic mossy fiber plasticity.
    Science (New York, N.Y.), 1998, Feb-27, Volume: 279, Issue:5355

    Topics: Afferent Pathways; Animals; Colforsin; Cyclic AMP; Cycloleucine; Cyclopropanes; Electric Stimulation; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Long-Term Potentiation; Mossy Fibers, Hippocampal; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission

1998
Group II and III metabotropic glutamate receptors modulate paired pulse depression in the rat dentate gyrus in vitro.
    European journal of pharmacology, 1997, Dec-04, Volume: 340, Issue:1

    Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Benzoates; Cycloleucine; Cyclopropanes; Dentate Gyrus; Evoked Potentials, Somatosensory; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Neuroprotective Agents; Rats; Receptors, Metabotropic Glutamate; Resorcinols

1997
Evidence for metabotropic glutamate receptor activation in the induction of depolarization-induced suppression of inhibition in hippocampal CA1.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Jul-01, Volume: 18, Issue:13

    Topics: 4-Aminopyridine; Amino Acids, Dicarboxylic; Animals; Benzoates; Calcium Channels; Cycloleucine; Cyclopropanes; Enzyme Inhibitors; Ethylmaleimide; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Male; Membrane Potentials; Neural Inhibition; Neuroprotective Agents; Patch-Clamp Techniques; Pyramidal Cells; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Signal Transduction; Synapses

1998
Metabotropic glutamate receptor agonists protect from oxygen-glucose deprivation- and colchicine-induced apoptosis in primary cultures of cerebellar granule cells.
    Neuroscience, 1999, Volume: 92, Issue:1

    Topics: Animals; Apoptosis; Cell Hypoxia; Cells, Cultured; Cerebellum; Colchicine; Cycloleucine; Cyclopropanes; Glucose; Glycine; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate

1999
Synaptic depression induced by pharmacological activation of metabotropic glutamate receptors in the perirhinal cortex in vitro.
    Neuroscience, 1999, Volume: 93, Issue:3

    Topics: Animals; Cycloleucine; Cyclopropanes; Electric Stimulation; Entorhinal Cortex; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Glycine; Hippocampus; Male; Neocortex; Neuronal Plasticity; Organ Culture Techniques; Propionates; Rats; Rats, Inbred Strains; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Synaptic Transmission; Temporal Lobe

1999
Metabotropic glutamate receptors and blockade of glial Krebs cycle depress glycinergic synaptic currents of mouse hypoglossal motoneurons.
    The European journal of neuroscience, 2000, Volume: 12, Issue:1

    Topics: Animals; Animals, Newborn; Aspartic Acid; Citric Acid Cycle; Cycloleucine; Cyclopropanes; Excitatory Postsynaptic Potentials; Female; Glycine; Hypoglossal Nerve; Male; Membrane Potentials; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred Strains; Motor Neurons; Neuroglia; Neuroprotective Agents; Patch-Clamp Techniques; Propionates; Receptors, Metabotropic Glutamate; Synapses

2000
Mobilisation of intracellular Ca2+ by mGluR5 metabotropic glutamate receptor activation in neonatal rat cultured dorsal root ganglia neurones.
    Neuropharmacology, 2000, Feb-14, Volume: 39, Issue:4

    Topics: Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Cells, Cultured; Cycloleucine; Cyclopropanes; Dantrolene; Fluorescence; Ganglia, Spinal; Glutamic Acid; Glycine; Indans; Phenylacetates; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ryanodine; Ryanodine Receptor Calcium Release Channel; Stereoisomerism

2000
Reducing conditions differentially affect the functional and structural properties of group-I and -II metabotropic glutamate receptors.
    Brain research, 2000, Jun-09, Volume: 867, Issue:1-2

    Topics: Amino Acids, Dicarboxylic; Animals; Anticonvulsants; Carbachol; Cell Membrane; Cerebellum; CHO Cells; Cholinergic Agonists; Colforsin; Cricetinae; Cyclic AMP; Cycloleucine; Cyclopropanes; Dimerization; Dithiothreitol; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Humans; Kidney; Neurons; Neuroprotective Agents; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Signal Transduction

2000
Regional distribution and pharmacological characteristics of [3H]N-acetyl-aspartyl-glutamate (NAAG) binding sites in rat brain.
    Neurochemistry international, 2001, Volume: 38, Issue:1

    Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Brain Chemistry; Carboxypeptidases; Cold Temperature; Cycloleucine; Cyclopropanes; Dipeptides; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamate Carboxypeptidase II; Glycine; Kainic Acid; Male; Nerve Tissue Proteins; Phosphoserine; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Tetrazoles

2001
Involvement of metabotropic glutamate receptors in ischemia-induced taurine release in the developing and adult hippocampus.
    Neurochemical research, 2000, Volume: 25, Issue:8

    Topics: Aging; Animals; Brain Ischemia; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamates; Glycine; Hippocampus; In Vitro Techniques; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred Strains; Neurons; Receptors, Metabotropic Glutamate; Taurine

2000
Metabotropic and NMDA glutamate receptor interactions with osmotic stimuli in supraoptic neurons.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 73, Issue:2

    Topics: Animals; Calcium Signaling; Cells, Cultured; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agonists; Female; Glycine; Image Processing, Computer-Assisted; Methoxyhydroxyphenylglycol; N-Methylaspartate; Neurons; Neurosecretory Systems; Osmolar Concentration; Pregnancy; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Supraoptic Nucleus

2002
Different roles of group I and group II metabotropic glutamate receptors on phencyclidine-induced dopamine release in the rat prefrontal cortex.
    Neuroscience letters, 2003, Jan-23, Volume: 336, Issue:3

    Topics: Animals; Anticonvulsants; Cycloleucine; Cyclopropanes; Dopamine; Dopamine Agents; Excitatory Amino Acid Antagonists; Extracellular Space; Glycine; Hallucinogens; Male; Microdialysis; Neuroprotective Agents; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Time Factors

2003
Mechanisms of glutamate receptor induced proliferation of astrocytes.
    Neuroreport, 2006, Dec-18, Volume: 17, Issue:18

    Topics: Animals; Animals, Newborn; Astrocytes; Cell Count; Cell Proliferation; Cells, Cultured; Cerebral Cortex; Cycloleucine; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycerophospholipids; Glycine; Indoles; Maleimides; Methoxyhydroxyphenylglycol; Phospholipase D; Pyridines; Rats; Rats, Wistar; Receptors, Glutamate; Tritium

2006
Involvement of Group II mGluRs in mossy fiber LTD.
    Synapse (New York, N.Y.), 2009, Volume: 63, Issue:12

    Topics: Amino Acids; Amino Acids, Dicarboxylic; Animals; Cycloleucine; Cyclopropanes; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Neural Inhibition; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synaptic Transmission; Xanthenes

2009