Page last updated: 2024-09-04

2-(1-octynyl)adenosine and n(6)-cyclopentyladenosine

2-(1-octynyl)adenosine has been researched along with n(6)-cyclopentyladenosine in 4 studies

Compound Research Comparison

Studies (2-(1-octynyl)adenosine)	Trials (2-(1-octynyl)adenosine)	Recent Studies (post-2010) (2-(1-octynyl)adenosine)	Studies (n(6)-cyclopentyladenosine)	Trials (n(6)-cyclopentyladenosine)	Recent Studies (post-2010) (n(6)-cyclopentyladenosine)
23	0	3	605	0	62

Protein Interaction Comparison

Protein	Taxonomy	n(6)-cyclopentyladenosine (IC50)
Adenosine receptor A1	Rattus norvegicus (Norway rat)	0.2256
Adenosine receptor A2b	Rattus norvegicus (Norway rat)	1.16
Adenosine receptor A1	Homo sapiens (human)	0.0027
Adenosine receptor A2a	Rattus norvegicus (Norway rat)	1.16

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (75.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (25.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cristalli, G; Eleuteri, A; Klotz, KN; Lohse, MJ; Vittori, S; Volpini, R	1
Abiru, T; Homma, H; Matsuda, A; Miyasaka, T; Nomoto, R; Shinozaki, M; Watanabe, Y; Yamaguchi, T	1
Jacobson, KA; van Galen, PJ; Williams, M	1
Donegan, RK; Lieberman, RL	1

Reviews

2 review(s) available for 2-(1-octynyl)adenosine and n(6)-cyclopentyladenosine

Article	Year
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3 Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship	1992
Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions. Journal of medicinal chemistry, 2016, Feb-11, Volume: 59, Issue:3 Topics: Adrenergic Agonists; Adrenergic Antagonists; Adrenergic beta-Antagonists; Animals; Drug Discovery; Glaucoma; Humans; Ligands; Protein Kinase Inhibitors; rho-Associated Kinases; Sympathomimetics	2016

Other Studies

2 other study(ies) available for 2-(1-octynyl)adenosine and n(6)-cyclopentyladenosine

Article	Year
2-Alkynyl derivatives of adenosine and adenosine-5'-N-ethyluronamide as selective agonists at A2 adenosine receptors. Journal of medicinal chemistry, 1992, Jun-26, Volume: 35, Issue:13 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Binding, Competitive; Blood Platelets; Brain Chemistry; Cell Membrane; Cells, Cultured; Humans; Platelet Aggregation; Radioligand Assay; Rats; Receptors, Purinergic	1992
Nucleosides and nucleotides. 103. 2-Alkynyladenosines: a novel class of selective adenosine A2 receptor agonists with potent antihypertensive effects. Journal of medicinal chemistry, 1992, Jan-24, Volume: 35, Issue:2 Topics: Adenosine; Adenosine Deaminase; Animals; Antihypertensive Agents; Blood Pressure; Brain; Female; Heart Rate; In Vitro Techniques; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Purinergic; Structure-Activity Relationship	1992

Article

Year

2-Alkynyl derivatives of adenosine and adenosine-5'-N-ethyluronamide as selective agonists at A2 adenosine receptors.

Journal of medicinal chemistry, 1992, Jun-26, Volume: 35, Issue:13

Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Binding, Competitive; Blood Platelets; Brain Chemistry; Cell Membrane; Cells, Cultured; Humans; Platelet Aggregation; Radioligand Assay; Rats; Receptors, Purinergic

1992

Nucleosides and nucleotides. 103. 2-Alkynyladenosines: a novel class of selective adenosine A2 receptor agonists with potent antihypertensive effects.

Journal of medicinal chemistry, 1992, Jan-24, Volume: 35, Issue:2

Topics: Adenosine; Adenosine Deaminase; Animals; Antihypertensive Agents; Blood Pressure; Brain; Female; Heart Rate; In Vitro Techniques; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Purinergic; Structure-Activity Relationship

1992