Page last updated: 2024-09-04

2-(1-octynyl)adenosine and glyburide

2-(1-octynyl)adenosine has been researched along with glyburide in 3 studies

Compound Research Comparison

Studies
(2-(1-octynyl)adenosine)
Trials
(2-(1-octynyl)adenosine)
Recent Studies (post-2010)
(2-(1-octynyl)adenosine)
Studies
(glyburide)
Trials
(glyburide)
Recent Studies (post-2010) (glyburide)
23036,5546201,344

Protein Interaction Comparison

ProteinTaxonomy2-(1-octynyl)adenosine (IC50)glyburide (IC50)
ATP-binding cassette sub-family C member 9Homo sapiens (human)0.22
Bile salt export pumpRattus norvegicus (Norway rat)5.7
Bile salt export pumpHomo sapiens (human)5.5333
Cytochrome P450 2C9 Homo sapiens (human)1.602
ATP-binding cassette sub-family C member 8Homo sapiens (human)0.0043
ATP-sensitive inward rectifier potassium channel 11Homo sapiens (human)0.1121
NACHT, LRR and PYD domains-containing protein 3 Mus musculus (house mouse)10
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)1.8

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Satoh, K; Taira, N; Yamada, H; Yoneyama, F1
Furukawa, S; Satoh, K; Taira, N1
Aihara, K; Kogi, K; Satoh, K; Taira, N; Yoneyama, F1

Other Studies

3 other study(ies) available for 2-(1-octynyl)adenosine and glyburide

ArticleYear
Vasodepressor mechanisms of 2-(1-octynyl)-adenosine (YT-146), a selective adenosine A2 receptor agonist, involve the opening of glibenclamide-sensitive K+ channels.
    European journal of pharmacology, 1992, Mar-24, Volume: 213, Issue:2

    Topics: Adenosine; Alkynes; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Female; Glyburide; Heart Rate; Injections, Intravenous; Male; Norepinephrine; Potassium Channels; Receptors, Purinergic; Theophylline

1992
Opening of ATP-sensitive K+ channels responsible for adenosine A2 receptor-mediated vasodepression does not involve a pertussis toxin-sensitive G protein.
    European journal of pharmacology, 1993, May-19, Volume: 236, Issue:2

    Topics: Adenosine; Adenosine Triphosphate; Alkynes; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Glyburide; GTP-Binding Proteins; Heart Rate; Male; Pertussis Toxin; Potassium Channels; Rats; Rats, Wistar; Receptors, Purinergic; Vagus Nerve; Virulence Factors, Bordetella

1993
Similarity and dissimilarity in mode and mechanism of action between YT-146, a selective adenosine receptor A2 agonist, and adenosine in isolated canine hearts.
    The Tohoku journal of experimental medicine, 1999, Volume: 188, Issue:1

    Topics: Adenosine; Alkynes; Animals; Atrioventricular Node; Blood Flow Velocity; Coronary Circulation; Dogs; Female; Glyburide; Heart; Heart Conduction System; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Papillary Muscles; Potassium Channel Blockers; Purinergic P1 Receptor Agonists; Vasodilator Agents

1999