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2-(1-octynyl)adenosine and adenosine-5'-(n-ethylcarboxamide)

2-(1-octynyl)adenosine has been researched along with adenosine-5'-(n-ethylcarboxamide) in 5 studies

Compound Research Comparison

Studies
(2-(1-octynyl)adenosine)
Trials
(2-(1-octynyl)adenosine)
Recent Studies (post-2010)
(2-(1-octynyl)adenosine)
Studies
(adenosine-5'-(n-ethylcarboxamide))
Trials
(adenosine-5'-(n-ethylcarboxamide))
Recent Studies (post-2010) (adenosine-5'-(n-ethylcarboxamide))
23031,3334133

Protein Interaction Comparison

ProteinTaxonomy2-(1-octynyl)adenosine (IC50)adenosine-5'-(n-ethylcarboxamide) (IC50)
Adenosine receptor A3Homo sapiens (human)0.0097
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.037
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.037
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.037
Adenosine receptor A1Rattus norvegicus (Norway rat)0.4498
Adenosine receptor A2aHomo sapiens (human)0.0336
Adenosine receptor A2bRattus norvegicus (Norway rat)0.0175
Adenosine receptor A1Homo sapiens (human)0.0007
Adenosine receptor A2aRattus norvegicus (Norway rat)0.0513
Adenosine receptor A1Gallus gallus (chicken)0.017

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abiru, T; Homma, H; Matsuda, A; Murayama, T; Nomura, Y; Watanabe, Y1
Cristalli, G; Eleuteri, A; Klotz, KN; Lohse, MJ; Vittori, S; Volpini, R1
Abiru, T; Homma, H; Matsuda, A; Miyasaka, T; Nomoto, R; Shinozaki, M; Watanabe, Y; Yamaguchi, T1
Jacobson, KA; van Galen, PJ; Williams, M1
Abiru, T; Aihara, K; Kogi, K; Matsuda, A; Watanabe, Y; Yamaguchi, T1

Reviews

1 review(s) available for 2-(1-octynyl)adenosine and adenosine-5'-(n-ethylcarboxamide)

ArticleYear
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
    Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3

    Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship

1992

Other Studies

4 other study(ies) available for 2-(1-octynyl)adenosine and adenosine-5'-(n-ethylcarboxamide)

ArticleYear
Nucleosides and nucleotides. 112. 2-(1-Hexyn-1-yl)adenosine-5'-uronamides: a new entry of selective A2 adenosine receptor agonists with potent antihypertensive activity.
    Journal of medicinal chemistry, 1992, Jul-24, Volume: 35, Issue:15

    Topics: Adenosine; Animals; Antihypertensive Agents; Brain; Male; Molecular Structure; Rats; Rats, Inbred SHR; Receptors, Purinergic; Substrate Specificity

1992
2-Alkynyl derivatives of adenosine and adenosine-5'-N-ethyluronamide as selective agonists at A2 adenosine receptors.
    Journal of medicinal chemistry, 1992, Jun-26, Volume: 35, Issue:13

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Binding, Competitive; Blood Platelets; Brain Chemistry; Cell Membrane; Cells, Cultured; Humans; Platelet Aggregation; Radioligand Assay; Rats; Receptors, Purinergic

1992
Nucleosides and nucleotides. 103. 2-Alkynyladenosines: a novel class of selective adenosine A2 receptor agonists with potent antihypertensive effects.
    Journal of medicinal chemistry, 1992, Jan-24, Volume: 35, Issue:2

    Topics: Adenosine; Adenosine Deaminase; Animals; Antihypertensive Agents; Blood Pressure; Brain; Female; Heart Rate; In Vitro Techniques; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Purinergic; Structure-Activity Relationship

1992
The antihypertensive effect of 2-alkynyladenosines and their selective affinity for adenosine A2 receptors.
    European journal of pharmacology, 1991, Apr-10, Volume: 196, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Alkynes; Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Brain; Cardiovascular System; Consciousness; Female; Heart Rate; Kinetics; Male; Rats; Rats, Inbred SHR; Receptors, Purinergic; Tritium; Vasodilator Agents

1991