2-((2-dimethylaminobenzyl)sulfinyl)benzimidazole has been researched along with omeprazole in 16 studies
| Studies (2-((2-dimethylaminobenzyl)sulfinyl)benzimidazole) | Trials (2-((2-dimethylaminobenzyl)sulfinyl)benzimidazole) | Recent Studies (post-2010) (2-((2-dimethylaminobenzyl)sulfinyl)benzimidazole) | Studies (omeprazole) | Trials (omeprazole) | Recent Studies (post-2010) (omeprazole) |
|---|---|---|---|---|---|
| 16 | 0 | 0 | 9,085 | 2,737 | 1,487 |
| Protein | Taxonomy | 2-((2-dimethylaminobenzyl)sulfinyl)benzimidazole (IC50) | omeprazole (IC50) |
|---|---|---|---|
| Mcl-1 | Homo sapiens (human) | 3.1448 | |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | 0.28 | |
| Potassium-transporting ATPase alpha chain 1 | Homo sapiens (human) | 1.45 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 2.315 | |
| Potassium-transporting ATPase subunit beta | Homo sapiens (human) | 1.45 | |
| WD repeat-containing protein 5 | Homo sapiens (human) | 1.7 | |
| Glutathione S-transferase omega-1 | Homo sapiens (human) | 4.6 | |
| Histone-lysine N-methyltransferase 2A | Homo sapiens (human) | 1.7 | |
| Muscarinic acetylcholine receptor | Cavia porcellus (domestic guinea pig) | 3.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (50.00) | 18.7374 |
| 1990's | 8 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adelstein, GW; Anglin, C; Decktor, DL; Gullikson, G; Haack, RA; Keith, RH; Price, DV; Tsai, H; Yen, CH; Yu, S | 1 |
| Igata, H; Okabe, S | 1 |
| Fusamoto, H; Kamada, T; Kawano, S; Nagano, K; Ogihara, T; Sato, N; Takei, Y; Tanimura, H; Tsuji, S | 1 |
| Ballabeni, V; Barocelli, E; Chiavarini, M; Impicciatore, M; Razzetti, R | 1 |
| Akimoto, Y; Kuwahara, K; Okabe, S; Yamasaki, S | 1 |
| Hotta, K; Ishihara, K; Komuro, Y; Ohara, S; Ohkawa, H; Okabe, H | 1 |
| Miyake, H; Okabe, S; Yamasaki, S | 1 |
| Okabe, S | 1 |
| Hara, K; Higaki, E; Higuchi, T; Okabe, S; Sato, M | 1 |
| Arisawa, T; Fukui, A; Goto, H; Hase, S; Kawabe, Y; Nakazawa, S; Osada, T; Segawa, K; Takano, K; Tsukamoto, Y | 1 |
| Akimoto, Y; Imada, J; Miyake, H; Okabe, S | 1 |
| Awane, Y; Miyake, H; Okabe, S | 1 |
| Hotta, K; Ichikawa, T; Ishihara, K; Komuro, Y; Ohara, S | 1 |
| Kamishiro, T; Kawaguchi, K; Masuda, M; Matsukura, H; Uchida, A | 1 |
| Inoue, K; Okabe, S; Takagi, K | 1 |
| Arakawa, T; Fukuda, T; Higuchi, K; Kobayashi, K; Koike, K; Satoh, H | 1 |
1 review(s) available for 2-((2-dimethylaminobenzyl)sulfinyl)benzimidazole and omeprazole
| Article | Year |
|---|---|
[Effects of gastric proton pump inhibitors on gastric secretion and peptic ulcers].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Bucladesine; Dogs; Duodenal Ulcer; Ethanol; Gastric Juice; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Histamine H2 Antagonists; Humans; Mice; Omeprazole; Parietal Cells, Gastric; Rats; Stomach Ulcer; Structure-Activity Relationship | 1986 |
15 other study(ies) available for 2-((2-dimethylaminobenzyl)sulfinyl)benzimidazole and omeprazole
| Article | Year |
|---|---|
Substituted 2-[(2-benzimidazolylsulfinyl)methyl]anilines as potential inhibitors of H+/K+ ATPase.
Topics: Adenosine Triphosphatases; Aniline Compounds; Animals; Dogs; Female; Gastric Acid; H(+)-K(+)-Exchanging ATPase; Structure-Activity Relationship | 1988 |
[Discovery and development of the proton pump inhibitor].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Benzimidazoles; Depression, Chemical; Gastric Acid; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Humans; Lansoprazole; Microsomes; Omeprazole; Rabeprazole | 1992 |
Effects of proton pump inhibitor on gastric mucosa hemodynamics and tissue oxygenation in anesthetized rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anesthesia; Animals; Benzimidazoles; Gastric Mucosa; Hemodynamics; Injections, Intraperitoneal; Male; Omeprazole; Oxygen Consumption; Oxyhemoglobins; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase | 1992 |
Omeprazole-like compounds on histamine-stimulated acid and peptic secretions in conscious dog and cat.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Benzimidazoles; Cats; Consciousness; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Drug Administration Routes; Duodenum; Gastric Acid; Gastric Mucosa; Histamine; Molecular Structure; Omeprazole; Pepsin A; Secretory Rate; Structure-Activity Relationship | 1992 |
Effects of a new benzimidazole derivative, NC-1300-O-3, on gastric secretion and gastroduodenal lesions in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Benzimidazoles; Dogs; Duodenal Ulcer; Female; Gastric Mucosa; Histamine; Immersion; In Vitro Techniques; Indomethacin; Male; Omeprazole; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Psychological | 1991 |
Effect of the proton pump inhibitor, NC-1300, on gastric mucus secretion in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Benzimidazoles; Gastric Mucosa; Glycoproteins; Hexoses; Ion Channels; Male; Mucus; Omeprazole; Protons; Rats; Rats, Inbred Strains | 1989 |
Effects of NC-1300, a gastric proton pump inhibitor, on healing of acetic acid-induced gastric ulcers in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetates; Administration, Oral; Animals; Anti-Ulcer Agents; Benzimidazoles; Indomethacin; Male; Omeprazole; Rats; Stomach Ulcer | 1989 |
Biochemical and pharmacological analysis of 2-[(2-dimethylaminobenzyl)sulfinyl] benzimidazole (NC-1300), a new proton pump inhibitor.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetylcholine; Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Duodenum; Gastric Mucosa; Guinea Pigs; H(+)-K(+)-Exchanging ATPase; Heart Rate; Histamine; Ileum; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Omeprazole; Peptic Ulcer; Rabbits; Rats; Stress, Physiological | 1986 |
The effect of a new gastric proton pump inhibitor on serotonin-induced gastric mucosal lesions in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Benzimidazoles; Gastric Juice; Gastric Mucosa; Male; Omeprazole; Peptic Ulcer; Rats; Rats, Inbred Strains; Regional Blood Flow; Serotonin | 1988 |
Effects of NC-1300 and its degradation products on gastric secretion and HCl.ethanol-induced gastric lesions in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Benzimidazoles; Drug Stability; Ethanol; Gastric Acid; Gastric Juice; Gastric Mucosa; Hydrochloric Acid; Hydrogen-Ion Concentration; Ligation; Male; Omeprazole; Pylorus; Rats; Rats, Inbred Strains; Stomach Ulcer | 1987 |
Cytoprotective effects of NC-1300 and omeprazole on Hcl . ethanol-induced gastric lesions in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Benzimidazoles; Ethanol; Ethylmaleimide; Gastric Juice; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Omeprazole; Rats; Rats, Inbred Strains; Stomach Ulcer; Sulfones | 1986 |
Effect on gastric mucus of the proton pump inhibitor leminoprazole and its cytoprotective action against ethanol-induced gastric injury in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Benzimidazoles; Cell Survival; Gastric Mucosa; Male; Mucins; Mucus; Omeprazole; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 1994 |
Cytoprotective effect of NC-1300-O-3 against gastric lesions induced by necrotizing agents in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Capillary Permeability; Dose-Response Relationship, Drug; Ethanol; Gastric Mucosa; Glutathione; Hexosamines; Male; Membrane Potentials; Omeprazole; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 1994 |
Effect of NC-1300-O-3 on healing of acetic acid-induced gastric ulcers in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Benzimidazoles; Gastric Acid; Gastric Mucosa; Histamine; Indomethacin; Male; Omeprazole; Rats; Rats, Inbred Strains; Stomach Ulcer | 1993 |
NC-1300, a proton-pump inhibitor, requires gastric acid to exert cytoprotection in rat gastric mucosa.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Benzimidazoles; Cell Survival; Ethanol; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Male; Omeprazole; Proton Pumps; Pylorus; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Stomach Ulcer | 1993 |