Page last updated: 2024-08-24

1h-tetrazole and pyrroles

1h-tetrazole has been researched along with pyrroles in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fotsch, C; St Jean, DJ1
Limbach, M1
Demopoulos, VJ; Koukoulitsa, C; Nicolaou, I; Pegklidou, K1
He, XY; Hou, L; Jiang, S; Liu, S; Qiu, J; Xie, L; Zou, P1
Hof, F; Pinter, T; Simhadri, C1

Reviews

2 review(s) available for 1h-tetrazole and pyrroles

ArticleYear
Mitigating heterocycle metabolism in drug discovery.
    Journal of medicinal chemistry, 2012, Jul-12, Volume: 55, Issue:13

    Topics: Animals; Biotransformation; Databases, Factual; Drug Discovery; Drug Interactions; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Pharmaceutical Preparations; Rats

2012
5-(pyrrolidin-2-yl)-1H-tetrazole and 5-[(pyrrolidin-2-yl)methyl]-1H-tetrazole: proline surrogates with increased potential in asymmetric catalysis.
    Chemistry & biodiversity, 2006, Volume: 3, Issue:2

    Topics: Catalysis; Proline; Pyrroles; Pyrrolidines; Stereoisomerism; Tetrazoles

2006

Other Studies

3 other study(ies) available for 1h-tetrazole and pyrroles

ArticleYear
Design and synthesis of novel series of pyrrole based chemotypes and their evaluation as selective aldose reductase inhibitors. A case of bioisosterism between a carboxylic acid moiety and that of a tetrazole.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Aldehyde Reductase; Animals; Carboxylic Acids; Drug Design; Enzyme Inhibitors; Female; Male; Molecular Structure; Pyrroles; Rats; Rats, Inbred F344; Stereoisomerism; Structure-Activity Relationship; Tetrazoles

2010
Design, synthesis and biological evaluation of 3-substituted 2,5-dimethyl-N-(3-(1H-tetrazol-5-yl)phenyl)pyrroles as novel potential HIV-1 gp41 inhibitors.
    Bioorganic & medicinal chemistry, 2011, Nov-15, Volume: 19, Issue:22

    Topics: Anti-HIV Agents; Binding Sites; HIV Envelope Protein gp41; HIV-1; Humans; Pyrroles; Structure-Activity Relationship; Tetrazoles

2011
Dissecting the complex recognition interfaces of potent tetrazole- and pyrrole-based anion binders.
    The Journal of organic chemistry, 2013, May-17, Volume: 78, Issue:10

    Topics: Amides; Anions; Models, Molecular; Molecular Structure; Pyrroles; Tetrazoles

2013