1h-benzotriazole-5-carboxylic acid has been researched along with trimethoprim in 1 studies
*Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported. [MeSH]
*Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bastien, D; Ebert, MC; Forge, D; Huang, TL; Kadnikova, N; Mayence, A; Pelletier, JN; Perron, F; Toulouse, J; Vanden Eynde, JJ | 1 |
1 other study(ies) available for 1h-benzotriazole-5-carboxylic acid and trimethoprim
| Article | Year |
|---|---|
Fragment-based design of symmetrical bis-benzimidazoles as selective inhibitors of the trimethoprim-resistant, type II R67 dihydrofolate reductase.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Benzimidazoles; Catalytic Domain; Cell Line; Cell Proliferation; Drug Design; Drug Resistance, Bacterial; Enzyme Assays; Fibroblasts; Folic Acid Antagonists; Humans; Kinetics; Mice; Models, Molecular; Protein Binding; Recombinant Proteins; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Trimethoprim | 2012 |