1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and vasoactive intestinal peptide

Topics: 1-Methyl-3-isobutylxanthine; Animals; Catechols; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Estrus; Female; Guanylate Cyclase; In Vitro Techniques; Mice; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Phosphodiesterase Inhibitors; Purinones; Quinoxalines; Synaptic Transmission; Vasoactive Intestinal Peptide; Vasodilator Agents

Topics: Animals; Apamin; Colon; Female; Indazoles; Muscle Relaxation; Muscle, Smooth; Myenteric Plexus; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Pituitary Adenylate Cyclase-Activating Polypeptide; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I; Receptors, Pituitary Hormone; Receptors, Vasoactive Intestinal Peptide; Tetrodotoxin; Vasoactive Intestinal Peptide

Topics: Adenine; Adenylyl Cyclase Inhibitors; Amidines; Animals; Arginine; Benzylamines; Carbazoles; Colforsin; Cyclic AMP; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastric Fundus; In Vitro Techniques; Indoles; Isoquinolines; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Oxadiazoles; Protein Kinase Inhibitors; Pyrroles; Quinoxalines; Sulfonamides; Swine; Thionucleotides; Vasoactive Intestinal Peptide

Topics: Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Male; Muscle Relaxation; Neuropeptides; Nitroarginine; Oxadiazoles; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Quinoxalines; Rats; Rats, Wistar; Rectum; Vasoactive Intestinal Peptide

Topics: Animals; Atropine; Cyclic GMP; Enteric Nervous System; Enzyme Inhibitors; Esophagogastric Junction; Female; Gastrointestinal Motility; Guanylate Cyclase; In Vitro Techniques; Male; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Smooth; Nitric Oxide; Opossums; Oxadiazoles; Parasympatholytics; Quinoxalines; Vasoactive Intestinal Peptide

Topics: Animals; Apamin; Carbachol; Cholinergic Agonists; Chymotrypsin; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; Guanylate Cyclase; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle Relaxation; Neuropeptides; Neurotransmitter Agents; Nitroarginine; Oxadiazoles; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Quinoxalines; Vasoactive Intestinal Peptide

Topics: Animals; Atropine; Enteric Nervous System; Enzyme Inhibitors; Esophagus; Galanin; Gastrointestinal Agents; Hexamethonium; Hydrazines; Male; Motor Neurons; Muscle Contraction; Muscle, Skeletal; Muscle, Smooth; Nicotinic Antagonists; Nitric Oxide Donors; Nitroarginine; Nitrogen Oxides; Oxadiazoles; Parasympatholytics; Quinoxalines; Rats; Rats, Wistar; Serotonin; Tetrodotoxin; Tubocurarine; Vagus Nerve; Vasoactive Intestinal Peptide

Topics: Animals; Carbazoles; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; Gastrointestinal Agents; Hydrazines; In Vitro Techniques; Indoles; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Nitrogen Oxides; Okadaic Acid; Oxadiazoles; Phosphodiesterase Inhibitors; Phosphoprotein Phosphatases; Purinones; Pyrroles; Quinoxalines; Rats; Rats, Wistar; Synaptic Transmission; Vasoactive Intestinal Peptide

Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Binding, Competitive; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrous Cycle; Female; Guanylate Cyclase; Imidazoles; In Vitro Techniques; Isoproterenol; Muscle Relaxation; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Oviducts; Oxadiazoles; Pituitary Adenylate Cyclase-Activating Polypeptide; Purinones; Quinoxalines; Radioligand Assay; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swine; Tritium; Vasoactive Intestinal Peptide

Topics: Adrenergic beta-Agonists; Amylases; Animals; Arginine; Autonomic Denervation; Bethanechol; Enzyme Inhibitors; Female; Gastrointestinal Agents; Guanylate Cyclase; In Vitro Techniques; Isoproterenol; Neuropeptide Y; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Parasympathomimetics; Parotid Gland; Quinoxalines; Rats; Rats, Sprague-Dawley; Vasoactive Intestinal Peptide

Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Apamin; Capsaicin; Charybdotoxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Female; Guanylate Cyclase; Male; Muscle, Smooth; Neurons, Afferent; Neuropeptide Y; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-Conotoxin GVIA; Oxadiazoles; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium Channels, Calcium-Activated; Quinoxalines; Receptors, Calcitonin Gene-Related Peptide; Receptors, Peptide; Receptors, Vasoactive Intestinal Peptide; Rolipram; Sensory Receptor Cells; Swine; Tetraethylammonium; Ureter; Vasoactive Intestinal Peptide

Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cats; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Esophagogastric Junction; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Molsidomine; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxadiazoles; Quinoxalines; Signal Transduction; Vasoactive Intestinal Peptide

Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Imines; Male; Mice; Mice, Inbred mdx; Muscle Relaxation; Muscle, Smooth; Muscular Dystrophy, Duchenne; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Organ Culture Techniques; Oxadiazoles; Quinoxalines; Receptors, Vasoactive Intestinal Peptide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach; Vasoactive Intestinal Peptide

Topics: Animals; Apamin; Blotting, Western; Colon; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; Gastrointestinal Motility; Guanylate Cyclase; Male; Mice; Mice, Knockout; Muscle Relaxation; Muscle, Smooth; Myenteric Plexus; Neural Inhibition; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Potassium Channel Blockers; Protein Subunits; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Small-Conductance Calcium-Activated Potassium Channels; Soluble Guanylyl Cyclase; Vasoactive Intestinal Peptide

Topics: Animals; Cyclic GMP; Dentate Gyrus; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Guanylate Cyclase; Hippocampus; Indazoles; Kainic Acid; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Vasoactive Intestinal Peptide