1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and nitrites

1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one has been researched along with nitrites in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (15.38)18.2507
2000's20 (76.92)29.6817
2010's2 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burke-Gaffney, A; Hellewell, PG1
Frölich, JC; Ikic, M; Raida, M; Tewes, KS; Tsikas, D1
Kawana, S; Miyamoto, A; Namiki, A; Ohshika, H; Yamamoto, S1
Haskó, G; Salzman, AL; Szabó, C; Zingarelli, B1
Brune, K; Hinz, B; Pahl, A1
Gandhi, CR; Kuddus, R; Uemura, T1
Barron, LA; Giardina, JB; Granger, JP; Khalil, RA1
Ball, SL; Duncan, A; Martin, W; McPate, MJ; Nelli, S; Rafique, KM; Shahidullah, M; Strachan, PD1
Cunha, FQ; Prado, WA; Schiavon, VF1
Bloodsworth, A; Chumley, PH; Eiserich, JP; Freeman, BA; Krishna, NR; Lim, DG; O'Donnell, VB; Schopfer, F; Sweeney, S; White, CR1
Kankuri, E; Kotikoski, H; Vapaatalo, H1
Favaloro, JL; Irvine, JC; Kemp-Harper, BK1
Cho, KW; Cui, Y; Kim, HJ; Koh, GY; Oh, HK; Park, JK1
Condorelli, G; Del Soldato, P; Dieterle, T; Gu, Y; Iwanaga, Y; Ongini, E; Peterson, KL; Presotto, C; Ross, J1
Khalil, RA; Orshal, JM1
Abebe, W; Maddux, WF1
Gupte, SA; McMurtry, IF; Oka, M; Okada, T1
Favaloro, JL; Kemp-Harper, BK2
Favaloro, JL; Irvine, JC; Kemp-Harper, BK; Widdop, RE1
Cuvelier, C; Demetter, P; Lefebvre, RA; Timmermans, JP; Van Crombruggen, K; Van Nassauw, L1
Alzawahra, WF; Liu, X; Samouilov, A; Talukder, MA; Zweier, JL1
Gladwin, M; Isenberg, JS; Shiva, S1
Kerschbaum, HH; Nimmervoll, B; Sacha, B; Svoboda, N1
Antunes-Rodrigues, J; Cunha, FQ; Elias, LL; Giusti-Paiva, A; Gomes, DA; Ventura, RR1
Almeida, R; Duarte, ID; Fontes, MA; Galdino, GS; Menezes, G; Perez, AC; Silva, G; Xavier, CH1

Other Studies

26 other study(ies) available for 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and nitrites

ArticleYear
Endogenous nitric oxide limits cytokine-induced damage of murine lung epithelial cells.
    The American journal of physiology, 1997, Volume: 272, Issue:4 Pt 1

    Topics: Animals; Arginine; Cytokines; Drug Combinations; Enzyme Inhibitors; Epithelium; Ethidium; Glutathione; Guanylate Cyclase; Interferon-gamma; Interleukin-1; Lung; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroso Compounds; Oxadiazoles; Quinoxalines; S-Nitrosoglutathione; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1997
Inhibition of platelet aggregation by S-nitroso-cysteine via cGMP-independent mechanisms: evidence of inhibition of thromboxane A2 synthesis in human blood platelets.
    FEBS letters, 1999, Jan-15, Volume: 442, Issue:2-3

    Topics: Arachidonic Acid; Aspirin; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Collagen; Cyclic GMP; Cysteine; Fatty Acids, Unsaturated; Glutathione; Guanylate Cyclase; Humans; Hydrazines; Inhibitory Concentration 50; Nitric Oxide; Nitrites; Nitroprusside; Nitroso Compounds; Oxadiazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Quinoxalines; S-Nitrosoglutathione; S-Nitrosothiols; Thromboxane A2

1999
Role of nitric oxide production in carbachol-induced negative chronotropy in cultured rat ventricular myocytes.
    European journal of pharmacology, 1999, Jan-29, Volume: 366, Issue:1

    Topics: Animals; Animals, Newborn; Atropine; Carbachol; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Heart Ventricles; Methylene Blue; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; omega-N-Methylarginine; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Signal Transduction

1999
Effects of a novel guanylyl cyclase inhibitor on the vascular actions of nitric oxide and peroxynitrite in immunostimulated smooth muscle cells and in endotoxic shock.
    Critical care medicine, 1999, Volume: 27, Issue:9

    Topics: Animals; Aorta; Cell Respiration; Cells, Cultured; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Interferon-gamma; Lipopolysaccharides; Male; Mice; Mitochondria; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitrites; Oxadiazoles; Oxidants; Quinoxalines; Rats; Rats, Wistar; Shock, Septic; Survival Analysis; Vasodilation

1999
Nitric oxide inhibits inducible nitric oxide synthase mRNA expression in RAW 264.7 macrophages.
    Biochemical and biophysical research communications, 2000, May-10, Volume: 271, Issue:2

    Topics: Animals; Cell Line; Cell Survival; Enzyme Inhibitors; Indicators and Reagents; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitroprusside; Oxadiazoles; Quinoxalines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2000
Endotoxin causes up-regulation of endothelin receptors in cultured hepatic stellate cells via nitric oxide-dependent and -independent mechanisms.
    British journal of pharmacology, 2000, Volume: 131, Issue:2

    Topics: Animals; Cell Line, Transformed; Cells, Cultured; Endotoxins; Lipopolysaccharides; Liver; Male; Nitric Oxide; Nitrites; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Time Factors; Up-Regulation

2000
High-salt diet enhances vascular reactivity in pregnant rats with normal and reduced uterine perfusion pressure.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:3 Pt 2

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Nitroprusside; Oxadiazoles; Phenylephrine; Pregnancy; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Uterus; Vasoconstrictor Agents; Vasodilator Agents

2001
Role of catalase in the smooth muscle relaxant actions of sodium azide and cyanamide.
    European journal of pharmacology, 2002, Jan-18, Volume: 435, Issue:1

    Topics: Amitrole; Animals; Aorta; Catalase; Cattle; Cyanamide; Electrochemistry; Enzyme Inhibitors; Hemoglobins; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxadiazoles; Penis; Quinoxalines; Rats; Rats, Wistar; Sodium Azide; Spectrophotometry

2002
Dual effect of local application of nitric oxide donors in a model of incision pain in rats.
    European journal of pharmacology, 2002, Apr-19, Volume: 441, Issue:1-2

    Topics: Animals; Disease Models, Animal; Diuretics, Osmotic; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Hindlimb; Hyperalgesia; Isosorbide; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Donors; Nitrites; Ointments; Oxadiazoles; Pain Threshold; Pain, Postoperative; Penicillamine; Quinoxalines; Rats; Rats, Wistar; Time Factors

2002
Nitrolinoleate, a nitric oxide-derived mediator of cell function: synthesis, characterization, and vasomotor activity.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Dec-10, Volume: 99, Issue:25

    Topics: Animals; Aorta, Thoracic; Chromatography, High Pressure Liquid; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Free Radical Scavengers; Guanylate Cyclase; Inflammation; Linoleic Acids; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Nitro Compounds; Oxadiazoles; Oxidation-Reduction; Oxyhemoglobins; Quinoxalines; Rats; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Vasodilation

2002
Incubation of porcine iris-ciliary bodies to study the mechanisms by which nitric oxide donors lower intraocular pressure.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:1

    Topics: Animals; Captopril; Ciliary Body; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Intraocular Pressure; Iris; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitro Compounds; Nitrogen Oxides; Oxadiazoles; Penicillamine; Phosphodiesterase Inhibitors; Purinones; Quinoxalines; Rabbits; S-Nitrosothiols; Spermine; Swine; Time Factors

2003
NO- activates soluble guanylate cyclase and Kv channels to vasodilate resistance arteries.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:6

    Topics: Animals; Arteries; Benzoates; Culture Techniques; Cysteine; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Guanylate Cyclase; Imidazoles; Male; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitroprusside; Oxadiazoles; Potassium; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Quinoxalines; Rats; Rats, Inbred WKY; Vascular Resistance; Vasodilation

2003
Activation of nitric oxide-cyclic guanosine monophosphate signaling in kidney by extracorporeal shock wave therapy.
    The Journal of urology, 2003, Volume: 170, Issue:6 Pt 1

    Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Kidney; Lithotripsy; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxadiazoles; Quinoxalines; Rabbits; Signal Transduction

2003
A nitric oxide-releasing derivative of enalapril, NCX 899, prevents progressive cardiac dysfunction and remodeling in hamsters with heart failure.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Cardiomyopathy, Dilated; Cricetinae; Cytoskeletal Proteins; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Enalapril; Endothelium, Vascular; Enzyme Inhibitors; Heart Failure; Hemodynamics; Male; Membrane Glycoproteins; Mesocricetus; Myocardial Contraction; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Oxadiazoles; Quinoxalines; Rabbits; Sarcoglycans; Ultrasonography; Vasoconstriction; Ventricular Remodeling

2004
Interleukin-6 impairs endothelium-dependent NO-cGMP-mediated relaxation and enhances contraction in systemic vessels of pregnant rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2004, Volume: 286, Issue:6

    Topics: Acetylcholine; Animals; Blotting, Western; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Estradiol; Female; Interleukin-6; Isometric Contraction; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxadiazoles; Phenylephrine; Pregnancy; Pregnancy, Animal; Progesterone; Quinoxalines; Rats; Rats, Sprague-Dawley; Vasodilator Agents

2004
Roles of nitric oxide and prostacyclin in triethyleneglycol dimethacrylate (TEGDMA)-induced vasorelaxation.
    Dental materials : official publication of the Academy of Dental Materials, 2006, Volume: 22, Issue:1

    Topics: Adenine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Aorta, Thoracic; Composite Resins; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Guanylate Cyclase; Male; Nitric Oxide; Nitrites; Oxadiazoles; Polyethylene Glycols; Polymethacrylic Acids; Quinoxalines; Rats; Rats, Inbred WKY; Vasodilator Agents

2006
Role of pentose phosphate pathway-derived NADPH in hypoxic pulmonary vasoconstriction.
    Pulmonary pharmacology & therapeutics, 2006, Volume: 19, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 6-Aminonicotinamide; Androsterone; Animals; Enzyme Inhibitors; Glucose-6-Phosphate; Glucosephosphate Dehydrogenase; Guanylate Cyclase; Hypoxia; In Vitro Techniques; Lung; Male; NADP; Nitrates; Nitrites; Oxadiazoles; Pentose Phosphate Pathway; Perfusion; Pulmonary Artery; Quinoxalines; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasoconstriction

2006
The nitroxyl anion (HNO) is a potent dilator of rat coronary vasculature.
    Cardiovascular research, 2007, Feb-01, Volume: 73, Issue:3

    Topics: Acetylcholine; Animals; Anions; Antioxidants; Calcitonin Gene-Related Peptide; Coronary Vessels; Dose-Response Relationship, Drug; Guanylate Cyclase; Heart Rate; Isoproterenol; Male; Myocardial Contraction; Nifedipine; Nitrites; Nitrogen Oxides; Oxadiazoles; Oxidation-Reduction; Peptide Fragments; Perfusion; Potassium; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Nitrite; Vasodilation

2007
Nitroxyl anion donor, Angeli's salt, does not develop tolerance in rat isolated aortae.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:4

    Topics: Animals; Aorta, Thoracic; Benzoates; Cyclic GMP-Dependent Protein Kinases; Cysteine; Drug Tolerance; Enzyme Inhibitors; Free Radical Scavengers; Hydrazines; Imidazoles; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitroglycerin; Oxadiazoles; Quinoxalines; Rats; Rats, Inbred WKY; Time Factors; Vasodilation

2007
Influence of soluble guanylate cyclase inhibition on inflammation and motility disturbances in DSS-induced colitis.
    European journal of pharmacology, 2008, Jan-28, Volume: 579, Issue:1-3

    Topics: Animals; Colitis; Cyclic GMP; Dextran Sulfate; Disease Models, Animal; Enzyme Inhibitors; Guanylate Cyclase; Inflammation; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Soluble Guanylyl Cyclase

2008
Heme proteins mediate the conversion of nitrite to nitric oxide in the vascular wall.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:2

    Topics: Animals; Aorta, Thoracic; Blood Pressure; Dose-Response Relationship, Drug; Electrochemistry; Electron Spin Resonance Spectroscopy; Endothelium-Dependent Relaxing Factors; Enzyme Inhibitors; Guanylate Cyclase; Heart Rate; Hemeproteins; In Vitro Techniques; Infusions, Intravenous; Male; Nitric Oxide; Nitrites; Oxadiazoles; Oxyhemoglobins; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Vasodilation

2008
Redox variants of NO (NO{middle dot} and HNO) elicit vasorelaxation of resistance arteries via distinct mechanisms.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: 4-Aminopyridine; Animals; Cyclic GMP; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Guanylate Cyclase; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Artery, Superior; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxadiazoles; Oxidation-Reduction; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vascular Resistance; Vasodilation; Vasodilator Agents

2009
Thrombospondin-1-CD47 blockade and exogenous nitrite enhance ischemic tissue survival, blood flow and angiogenesis via coupled NO-cGMP pathway activation.
    Nitric oxide : biology and chemistry, 2009, Volume: 21, Issue:1

    Topics: Analysis of Variance; Animals; Back; CD47 Antigen; Cyclic GMP; Enzyme Inhibitors; Gene Silencing; Ischemia; Male; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Nitric Oxide; Nitrites; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Signal Transduction; Surgical Flaps; Thrombospondin 1; Xanthine Dehydrogenase

2009
Sustained elevation of cyclic guanosine monophosphate induces apoptosis in microglia.
    Brain research bulletin, 2009, Dec-16, Volume: 80, Issue:6

    Topics: Animals; Apoptosis; Cell Death; Cell Line; Cell Membrane; Cell Nucleus; Cells, Cultured; Chromatin; Cyclic GMP; Enzyme Inhibitors; Intracellular Space; Mice; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; Nitrites; Oxadiazoles; Phosphatidylserines; Quaternary Ammonium Compounds; Quinoxalines

2009
Carbon monoxide and nitric oxide modulate hyperosmolality-induced oxytocin secretion by the hypothalamus in vitro.
    Bioscience reports, 2010, Jun-03, Volume: 30, Issue:5

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbon Monoxide; Enzyme Inhibitors; Hypothalamus; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroprusside; Osmotic Pressure; Oxadiazoles; Oxytocin; Quinoxalines; Rats; Rats, Wistar

2010
The Nitric oxide/CGMP/KATP pathway mediates systemic and central antinociception induced by resistance exercise in rats.
    The International journal of neuroscience, 2015, Volume: 125, Issue:10

    Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Glyburide; Guanidines; Guanylate Cyclase; KATP Channels; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Nociception; Ornithine; Oxadiazoles; Pain Measurement; Physical Conditioning, Animal; Quinoxalines; Rats; Signal Transduction

2015