1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one has been researched along with methylene blue in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (26.92) | 18.2507 |
| 2000's | 18 (69.23) | 29.6817 |
| 2010's | 1 (3.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, SJ; Wu, CC; Yen, MH | 1 |
| Holmes, EP; Krautmann, MJ; Maher, TJ; Venugopalan, CS | 1 |
| Hwang, TL; Teng, CM; Wu, CC | 1 |
| Cena, C; Di Stilo, A; Ermondi, G; Gasco, A; Gasco, AM; Visentin, S | 1 |
| Kawana, S; Miyamoto, A; Namiki, A; Ohshika, H; Yamamoto, S | 1 |
| Dasso, M; Rosenzweig, S; Spielman, AI; Yan, W | 1 |
| Budelmann, BU; Tu, Y | 2 |
| Rosenberg, R; Volke, V; Wegener, G | 1 |
| Duarte, ID; Ferreira, SH | 1 |
| Chen, IJ; Chiang, LC; Lin, CY; Lin, RJ; Shen, KP; Wu, BN | 1 |
| Chai, CY; Kao, LS; Tang, FI; Wang, Y; Wu, WC | 1 |
| Bnouham, M; Fischmeister, R; Hoerter, J; Legssyer, A; Mekhfi, H; Tahri, A; Ziyyat, A | 1 |
| Jeong, MS; Kim, CJ; Kim, KW; Park, EY; Park, JW; Shin, BS; Shin, MS; Woo, RS; Zhao, RJ | 1 |
| Fujimoto, S; Mori, M; Tsushima, H | 1 |
| Chen, CJ; Chen, JS; Chen, LW; Hsu, CM; Hwang, YC; Wang, JS | 1 |
| Jun, CH; Lee, TS; Sohn, UD | 1 |
| Ekerhovd, E; Norström, A | 1 |
| Altura, BM; Altura, BT; Li, J; Li, W | 1 |
| Cao, LH; Choi, DH; Kang, DG; Kim, JS; Kim, SJ; Lee, H; Lee, HS; Lee, JK | 1 |
| da-Silva, CA; Del Bel, EA; Echeverry, MB; Ferreira, FR; Salgado, ML | 1 |
| Cui, S; Liu, W; Shibamoto, T; Takano, H; Zhang, W; Zhao, Z | 1 |
| Capra, NF; Lee, J; Ro, JY; Zhang, Y | 1 |
| Bose, R; Cheng, ZQ; Jacobs, H; Kasian, K; Light, RB; Mink, SN; Santos Martinez, LE | 1 |
| Assreuy, J; Barja-Fidalgo, C; Fernandes, D; Heckert, BT; Lobo, AR; Nardi, GM; Pacheco, LK; Sordi, R; Villela, CG | 1 |
| Kang, YH; Morgan, KG; Shin, HM; Yang, IJ | 1 |
26 other study(ies) available for 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and methylene blue
| Article | Year |
|---|---|
Nitric oxide-independent activation of soluble guanylyl cyclase contributes to endotoxin shock in rats.
Topics: Animals; Aorta; Blood Pressure; Charybdotoxin; Dexamethasone; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Guanidines; Guanylate Cyclase; Heart Rate; In Vitro Techniques; Lipopolysaccharides; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Oxadiazoles; Quinoxalines; Rats; Rats, Inbred WKY; Shock, Septic; Tetraethylammonium | 1998 |
Involvement of nitric oxide in the mediation of NANC inhibitory neurotransmission of guinea-pig trachea.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Guinea Pigs; Male; Methemoglobin; Methylene Blue; Neural Inhibition; Nitric Oxide; Oxadiazoles; Quinoxalines; Receptors, Adrenergic; Receptors, Cholinergic; Synaptic Transmission; Trachea | 1998 |
Comparison of two soluble guanylyl cyclase inhibitors, methylene blue and ODQ, on sodium nitroprusside-induced relaxation in guinea-pig trachea.
Topics: Animals; Cyclic GMP; Drug Interactions; Enzyme Inhibitors; Guanylate Cyclase; Guinea Pigs; Methylene Blue; Mice; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Oxadiazoles; Quinoxalines; Signal Transduction; Solubility; Trachea; Vasodilator Agents | 1998 |
New 1,4-dihydropyridines conjugated to furoxanyl moieties, endowed with both nitric oxide-like and calcium channel antagonist vasodilator activities.
Topics: Animals; Aorta, Thoracic; Binding, Competitive; Calcium Channel Blockers; Cerebral Cortex; Dihydropyridines; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide Donors; Oxadiazoles; Quinoxalines; Radioligand Assay; Rats; Rats, Wistar; Structure-Activity Relationship; Vasodilator Agents | 1998 |
Role of nitric oxide production in carbachol-induced negative chronotropy in cultured rat ventricular myocytes.
Topics: Animals; Animals, Newborn; Atropine; Carbachol; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Heart Ventricles; Methylene Blue; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; omega-N-Methylarginine; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Signal Transduction | 1999 |
Possible novel mechanism for bitter taste mediated through cGMP.
Topics: Aminoquinolines; Animals; Caffeine; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Glycine Agents; Methylene Blue; Mice; Nitro Compounds; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Quaternary Ammonium Compounds; Quinoxalines; Signal Transduction; Strychnine; Sulfhydryl Reagents; Taste; Theophylline | 1999 |
Effects of L-arginine on the afferent resting activity in the cephalopod statocyst.
Topics: Action Potentials; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Arginine; Cyclic AMP; Cyclic GMP; Cystamine; DDT; Decapodiformes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Hair Cells, Vestibular; Imines; Immunosuppressive Agents; Male; Methylene Blue; Mollusca; NADP; NG-Nitroarginine Methyl Ester; Niacin; Nitric Oxide; Nitroarginine; Oxadiazoles; Postural Balance; Quinoxalines; Sodium Chloride | 1999 |
Endogenous nitric oxide decreases hippocampal levels of serotonin and dopamine in vivo.
Topics: Animals; Arginine; Dopamine; Enzyme Inhibitors; Extracellular Space; Hippocampus; Indazoles; Male; Methylene Blue; Microdialysis; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Serotonin | 2000 |
L-NAME causes antinociception by stimulation of the arginine-NO-cGMP pathway.
Topics: Analgesics; Animals; Arginine; Carrageenan; Cyclic GMP; Dinoprostone; Hyperalgesia; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Phosphodiesterase Inhibitors; Phthalazines; Quinoxalines; Rats; Rats, Wistar; Signal Transduction | 2000 |
Inhibitory effect of cyclic guanosine 3',5'-monophosphate (cGMP) on the afferent resting activity in the cephalopod statocyst.
Topics: Afferent Pathways; Animals; Cyclic GMP; Cystamine; Decapodiformes; Dibutyryl Cyclic GMP; Dideoxyadenosine; Enzyme Inhibitors; Imines; Methylene Blue; Mollusca; NG-Nitroarginine Methyl Ester; Niacin; Nitroarginine; Oxadiazoles; Quinoxalines; Sense Organs | 2000 |
A xanthine-based KMUP-1 with cyclic GMP enhancing and K(+) channels opening activities in rat aortic smooth muscle.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Aorta; Aorta, Thoracic; Blood Pressure; Cells, Cultured; Cromakalim; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Heart Rate; In Vitro Techniques; Methylene Blue; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Phosphoric Diester Hydrolases; Piperidines; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Solubility; Vasodilation; Vasodilator Agents; Xanthine; Xanthines | 2001 |
Nitric oxide reduces blood pressure in the nucleus tractus solitarius: a real time electrochemical study.
Topics: Animals; Arginine; Biosensing Techniques; Blood Pressure; Bradycardia; Cats; Computer Systems; Electrochemistry; Enzyme Inhibitors; Extracellular Space; Female; Guanosine Monophosphate; Guanylate Cyclase; Hemoglobins; Hypertension; Hypotension; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Pressoreceptors; Quinoxalines; Reflex; Sensitivity and Specificity; Solitary Nucleus; Tachycardia; Vagotomy | 2002 |
Arbutus unedo induces endothelium-dependent relaxation of the isolated rat aorta.
Topics: Animals; Aorta, Thoracic; Atropine; Carbachol; Dogs; Drug Interactions; Endothelium, Vascular; Ericaceae; In Vitro Techniques; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Norepinephrine; Oxadiazoles; Plant Extracts; Plant Roots; Quinoxalines; Rats; Rats, Wistar; Vasoconstriction; Vasodilation | 2002 |
Mechanism of nicotine-evoked release of 3H-noradrenaline in human cerebral cortex slices.
Topics: Adolescent; Adult; Arginine; Calcium; Calcium Channel Blockers; Cerebral Cortex; Dihydro-beta-Erythroidine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoxetine; Ganglionic Stimulants; Guanylate Cyclase; Humans; In Vitro Techniques; Indazoles; Male; Mecamylamine; Methylene Blue; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nicotine; Nicotinic Antagonists; Nitrendipine; Nitric Oxide Synthase; Norepinephrine; omega-Conotoxin GVIA; Oxadiazoles; Purinones; Quinoxalines; Tetrodotoxin; Tritium; Tubocurarine | 2002 |
Mechanisms underlying the hydrogen peroxide-induced, endothelium-independent relaxation of the norepinephrine-contraction in guinea-pig aorta.
Topics: Animals; Aorta, Thoracic; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Guinea Pigs; Hydrogen Peroxide; In Vitro Techniques; Male; Methylene Blue; Myosin Light Chains; Nitroglycerin; Norepinephrine; Oxadiazoles; Phosphorylation; Purinones; Quinoxalines; Rats; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2003 |
Burn-induced lung damage in rat is mediated by a nitric oxide/cGMP system.
Topics: Animals; Base Sequence; Burns; Cyclic GMP; Enzyme Inhibitors; Female; Gene Expression; Guanylate Cyclase; Lung; Lung Injury; Male; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroprusside; Oxadiazoles; Peroxidase; Quinoxalines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction | 2003 |
NO/cyclic GMP pathway mediates the relaxation of feline lower oesophageal sphincter.
Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cats; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Esophagogastric Junction; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Molsidomine; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxadiazoles; Quinoxalines; Signal Transduction; Vasoactive Intestinal Peptide | 2003 |
Involvement of a nitric oxide-cyclic guanosine monophosphate pathway in control of fallopian tube contractility.
Topics: Adult; Cyclic GMP; Enzyme Inhibitors; Fallopian Tubes; Female; Guanylate Cyclase; Humans; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Quinoxalines; Spermine | 2004 |
Peroxynitrite-induced relaxation in isolated rat aortic rings and mechanisms of action.
Topics: Animals; Aorta; Calcium Chloride; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; In Vitro Techniques; Male; Marine Toxins; Methylene Blue; Oxadiazoles; Oxazoles; Peroxynitrous Acid; Phenylephrine; Piperazines; Potassium; Purines; Quinoxalines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Tetraethylammonium; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2005 |
Endothelium-dependent induction of vasorelaxation by the butanol extract of Phellinus igniarius in isolated rat aorta.
Topics: Animals; Aorta; Atropine; Butanols; Cyclic GMP; Diltiazem; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; In Vitro Techniques; Indomethacin; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Oxadiazoles; Polyporaceae; Propranolol; Quinoxalines; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Vasodilation; Vasodilator Agents; Verapamil | 2006 |
Intracerebroventricular administration of nitric oxide-sensitive guanylyl cyclase inhibitors induces catalepsy in mice.
Topics: Animals; Arginine; Behavior, Animal; Catalepsy; Corpus Striatum; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Indazoles; Injections, Intraventricular; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Time Factors | 2007 |
N(G)-nitro-L-arginine methyl ester, but not methylene blue, attenuates anaphylactic hypotension in anesthetized mice.
Topics: Anaphylaxis; Anesthesia; Animals; Blood Pressure; Enzyme Inhibitors; Guanylate Cyclase; Hypertension; Liver Circulation; Male; Methylene Blue; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Ovalbumin; Oxadiazoles; Quinoxalines | 2007 |
Role of soluble guanylate cyclase in the trigeminal subnucleus caudalis in capsaicin-induced muscle hypersensitivity.
Topics: Analysis of Variance; Animals; Area Under Curve; Behavior, Animal; Capsaicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Hyperalgesia; Male; Masseter Muscle; Methylene Blue; Mice; Nerve Tissue Proteins; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Sensory Thresholds; Soluble Guanylyl Cyclase; Time Factors; Trigeminal Caudal Nucleus | 2007 |
Lysozyme, a mediator of sepsis that produces vasodilation by hydrogen peroxide signaling in an arterial preparation.
Topics: Aminoquinolines; Animals; Carotid Artery, Internal; Catalase; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Free Radical Scavengers; Guanylate Cyclase; Humans; Hydrogen Peroxide; Hydroquinones; In Vitro Techniques; Indomethacin; Mannitol; Mesenteric Artery, Superior; Methylene Blue; Muramidase; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxadiazoles; Phenylephrine; Prostaglandins; Protein Kinase Inhibitors; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Sepsis; Signal Transduction; Soluble Guanylyl Cyclase; Thionucleotides; Time Factors; Vasoconstrictor Agents; Vasodilation | 2008 |
Late, but not early, inhibition of soluble guanylate cyclase decreases mortality in a rat sepsis model.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Cecum; Cyclic GMP; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Female; Guanylate Cyclase; Methylene Blue; Mortality; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; RNA, Messenger; Sepsis; Vasoconstriction | 2009 |
Cinnamyl alcohol attenuates vasoconstriction by activation of K⁺ channels via NO-cGMP-protein kinase G pathway and inhibition of Rho-kinase.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dipeptides; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Phenylephrine; Phosphorylation; Potassium Channel Blockers; Potassium Channels; Propanols; Quinoxalines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Vasoconstriction; Vasodilation | 2012 |