Compounds > 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one

1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and colforsin

1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one has been researched along with colforsin in 28 studies

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (17.86)	18.2507
2000's	16 (57.14)	29.6817
2010's	7 (25.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Katusic, ZS; Onoue, H	1
Polte, T; Schröder, H	1
Carlson, EJ; Drewett, JG; Kreklau, EL	1
Gong, GX; Scholz, PM; Straznicka, M; Tse, J; Weiss, HR; Yan, L	1
Gupte, SA; Phillibert, D; Rupawalla, T; Wolin, MS	1
Dick, JM; Lefebvre, RA	1
Berggren, PO; Cooney, RV; Sjöholm, A	1
Eguchi, D; Katusic, ZS	1
Gupte, SA; Okada, T	1
Argibay, J; Hoebeke, J; Nascimento, JH; Peineau, N; Sallé, L	1
Jacobson, KL; Ott, SM; Singh, JC; Watson, EL	1
Bessard, G; Bréant, D; Caron, F; Corompt, E; Devillier, P	1
Bers, DM; Katoh, H; Ziolo, MT	1
Chen, YH; LaPolt, PS; Ngo, A; Tafoya, M	1
Diamond, J; Sandirasegarane, L	1
Barahona, MV; Benedito, S; García-Sacristán, A; Hernández, M; Martínez, AC; Orensanz, LM; Prieto, D; Recio, P; Rivera, L	1
MacNaughton, WK; Skinn, AC	1
Elmedal Laursen, B; Mulvany, MJ; Simonsen, U	1
Antunes, E; Baracat, JS; Claudino, MA; De Nucci, G; Priviero, FB; Teixeira, CE; Webb, RC	1
Genade, S; Genis, A; Huisamen, B; Lochner, A; Ytrehus, K	1
Goy, D; Gummersbach, C; Hemmrich, K; Kröncke, KD; Pallua, N; Paul, NE; Suschek, CV	1
Moonen, RM; Villamor, E	1
Blouquit-Laye, S; Braun, C; Chinet, T; Dannhoffer, L; Dinh-Xuan, AT; Sage, E	1
Agazatian, D; Froehlich, O; Kim, YH; Pech, V; Thumova, M; Verlander, JW; Wall, SM; Wang, X	1
Bae, H; Bang, H; Kim, JH; Kim, K; Kim, T; Ko, JH; Lee, HJ; Lim, I	1
Alexander, SP; Garle, MJ; Randall, MD; Roberts, RE; Wong, PS	1
Fernández-Fernández, D; Kroker, KS; Rosenbrock, H	1

Other Studies

28 other study(ies) available for 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and colforsin

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
The effect of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ) and charybdotoxin (CTX) on relaxations of isolated cerebral arteries to nitric oxide. Brain research, 1998, Feb-23, Volume: 785, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Bradykinin; Cerebral Arteries; Charybdotoxin; Colforsin; Cyclic GMP; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; In Vitro Techniques; Isometric Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitrogen Oxides; Oxadiazoles; Quinoxalines; Uridine Triphosphate	1998
Cyclic AMP mediates endothelial protection by nitric oxide. Biochemical and biophysical research communications, 1998, Oct-20, Volume: 251, Issue:2 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Alkaloids; Animals; Carbazoles; Cattle; Cell Line; Cell Survival; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic N-Oxides; Dideoxyadenosine; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Imidazoles; Indoles; Kinetics; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Pulmonary Artery; Pyrroles; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; Tumor Necrosis Factor-alpha	1998
Nitric oxide inhibits human aldosteronogenesis without guanylyl cyclase stimulation. Molecular and cellular endocrinology, 1999, Jul-20, Volume: 153, Issue:1-2 Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Animals; Cell Line; Colforsin; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Humans; Hydroxycholesterols; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Nitroso Compounds; Oxadiazoles; PC12 Cells; Quinoxalines; Rats	1999
Cyclic GMP and cyclic AMP induced changes in control and hypertrophic cardiac myocyte function interact through cyclic GMP affected cyclic-AMP phosphodiesterases. Canadian journal of physiology and pharmacology, 1999, Volume: 77, Issue:6 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cardiomegaly; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Heart; Milrinone; Oxadiazoles; Oxygen Consumption; Purinones; Quinoxalines	1999
NADPH and heme redox modulate pulmonary artery relaxation and guanylate cyclase activation by NO. The American journal of physiology, 1999, Volume: 277, Issue:6 Topics: Animals; Cattle; Colforsin; Cyclic GMP; Electron Transport; Enzyme Activation; Enzyme Inhibitors; Ferricyanides; Flavoproteins; Glutathione; Guanylate Cyclase; Heme; In Vitro Techniques; NADH, NADPH Oxidoreductases; NADP; Nitric Oxide; Oxadiazoles; Oxidation-Reduction; Penicillamine; Pentose Phosphate Pathway; Pulmonary Artery; Quinoxalines; Reactive Oxygen Species; Sulfhydryl Compounds	1999
Interplay between nitric oxide and vasoactive intestinal polypeptide in the pig gastric fundus smooth muscle. European journal of pharmacology, 2000, Jun-02, Volume: 397, Issue:2-3 Topics: Adenine; Adenylyl Cyclase Inhibitors; Amidines; Animals; Arginine; Benzylamines; Carbazoles; Colforsin; Cyclic AMP; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastric Fundus; In Vitro Techniques; Indoles; Isoquinolines; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Oxadiazoles; Protein Kinase Inhibitors; Pyrroles; Quinoxalines; Sulfonamides; Swine; Thionucleotides; Vasoactive Intestinal Peptide	2000
gamma-tocopherol partially protects insulin-secreting cells against functional inhibition by nitric oxide. Biochemical and biophysical research communications, 2000, Oct-22, Volume: 277, Issue:2 Topics: Adenylyl Cyclases; Animals; Calcium; Calcium Channels; Carbachol; Cell Division; Cell Line; Cell Survival; Cholinergic Agonists; Colforsin; Cyclic GMP; Enzyme Inhibitors; Insulin; Insulin Secretion; Insulinoma; Interleukin-1; Islets of Langerhans; Models, Chemical; Nitric Oxide; Nitrogen Oxides; Oxadiazoles; Phorbol Esters; Protein Kinase C; Quinoxalines; Rats; Spermine; Type C Phospholipases; Vitamin E	2000
Inhibitory effect of valves on endothelium-dependent relaxations to calcium ionophore in canine saphenous vein. American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcimycin; Calcium; Colforsin; Cyclic GMP; Cyclooxygenase Inhibitors; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Hydrazines; In Vitro Techniques; Indomethacin; Ionophores; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Potassium Chloride; Quinoxalines; Saphenous Vein; Vasoconstrictor Agents; Vasodilation	2001
Prostaglandins and nitric oxide mediate superoxide-induced myocardial contractile dysfunction in isolated rat hearts. Journal of molecular and cellular cardiology, 2001, Volume: 33, Issue:6 Topics: 1-Methyl-3-isobutylxanthine; Animals; Aspartate Aminotransferases; Colforsin; Enzyme Inhibitors; Heart; Myocardial Contraction; Myocardium; Nitrates; Nitric Acid; Nitroarginine; Nitroglycerin; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Prostaglandins; Quinoxalines; Rats; Superoxides; Thromboxane A2; Vasodilator Agents	2001
cGMP-mediated inhibition of cardiac L-type Ca(2+) current by a monoclonal antibody against the M(2) ACh receptor. American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:4 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Antibodies, Monoclonal; Autoantibodies; Calcium Channels, L-Type; Colforsin; Cyclic GMP; Enzyme Inhibitors; Guanosine; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Isoproterenol; Membrane Potentials; Muscle Fibers, Skeletal; Myocardium; Oxadiazoles; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Quinoxalines; Receptor, Muscarinic M2; Receptors, Muscarinic	2001
Nitric oxide inhibition of cAMP synthesis in parotid acini: regulation of type 5/6 adenylyl cyclase. Cellular signalling, 2001, Volume: 13, Issue:10 Topics: Adenylyl Cyclases; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoenzymes; Isoproterenol; Mice; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Parotid Gland; Phosphoric Diester Hydrolases; Quinoxalines; Thapsigargin; Triazoles	2001
Relaxation and modulation of cyclic AMP production in response to atrial natriuretic peptides in guinea pig tracheal smooth muscle. European journal of pharmacology, 2001, Nov-02, Volume: 430, Issue:2-3 Topics: Adenylyl Cyclases; Animals; Apamin; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Glyburide; Guanylate Cyclase; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Natriuretic Peptide, C-Type; Nitroprusside; Oxadiazoles; Peptide Fragments; Peptides; Phosphodiesterase Inhibitors; Potassium Channel Blockers; Quinoxalines; Rolipram; Trachea	2001
Expression of inducible nitric oxide synthase depresses beta-adrenergic-stimulated calcium release from the sarcoplasmic reticulum in intact ventricular myocytes. Circulation, 2001, Dec-11, Volume: 104, Issue:24 Topics: Animals; Calcium; Colforsin; Cyclic GMP; Enzyme Inhibitors; Guanidines; Guanylate Cyclase; Heart Failure; Heart Ventricles; Humans; Lipopolysaccharides; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Sarcoplasmic Reticulum	2001
Effects of nitric oxide and cGMP on inhibin A and inhibin subunit mRNA levels from cultured rat granulosa cells. Fertility and sterility, 2003, Volume: 79 Suppl 1 Topics: Animals; Blotting, Northern; Colforsin; Cyclic GMP; Dibutyryl Cyclic GMP; Enzyme Inhibitors; Estradiol; Female; Follicle Stimulating Hormone; Granulosa Cells; Inhibins; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; RNA, Messenger	2003
Pertussis toxin-sensitive G protein but not NO/cGMP pathway mediates the negative inotropic effect of carbachol in adult rat cardiomyocytes. Pharmacology, 2004, Volume: 70, Issue:1 Topics: Adenylyl Cyclases; Animals; Carbachol; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Electric Stimulation; GTP-Binding Proteins; Injections, Intraperitoneal; Isoproterenol; Male; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide Synthase; omega-N-Methylarginine; Oxadiazoles; Pertussis Toxin; Quinoxalines; Rats; Time Factors	2004
Heterogeneity of neuronal and smooth muscle receptors involved in the VIP- and PACAP-induced relaxations of the pig intravesical ureter. British journal of pharmacology, 2004, Volume: 141, Issue:1 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Apamin; Capsaicin; Charybdotoxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Female; Guanylate Cyclase; Male; Muscle, Smooth; Neurons, Afferent; Neuropeptide Y; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-Conotoxin GVIA; Oxadiazoles; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium Channels, Calcium-Activated; Quinoxalines; Receptors, Calcitonin Gene-Related Peptide; Receptors, Peptide; Receptors, Vasoactive Intestinal Peptide; Rolipram; Sensory Receptor Cells; Swine; Tetraethylammonium; Ureter; Vasoactive Intestinal Peptide	2004
Nitric oxide inhibits cAMP-dependent CFTR trafficking in intestinal epithelial cells. American journal of physiology. Gastrointestinal and liver physiology, 2005, Volume: 289, Issue:4 Topics: Cell Line; Cell Membrane; Cell Membrane Permeability; Chlorides; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Epithelial Cells; Fluorescent Antibody Technique; Guanylate Cyclase; Humans; Intestinal Mucosa; Intestines; Isoquinolines; Nitric Oxide; Nitric Oxide Donors; Nocodazole; Oxadiazoles; Quinoxalines; Sulfonamides	2005
Involvement of guanylyl cyclase, protein kinase A and Na+ K+ ATPase in relaxations of bovine isolated bronchioles induced by GEA 3175, an NO donor. Pulmonary pharmacology & therapeutics, 2006, Volume: 19, Issue:3 Topics: Animals; Bronchi; Calcium; Cattle; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Guanylate Cyclase; In Vitro Techniques; Molsidomine; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; Ouabain; Oxadiazoles; Peptides; Potassium; Quinoxalines; S-Nitrosoglutathione; Serotonin; Sodium-Potassium-Exchanging ATPase; Thionucleotides; Triazoles	2006
Stimulation of soluble guanylyl cyclase by BAY 41-2272 relaxes anococcygeus muscle: interaction with nitric oxide. European journal of pharmacology, 2006, Jan-13, Volume: 530, Issue:1-2 Topics: Animals; Carbachol; Carbolines; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Enzyme Activation; Enzyme Inhibitors; Guanylate Cyclase; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroglycerin; Oxadiazoles; Pyrazoles; Pyridines; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Tadalafil; Tetrodotoxin	2006
Melatonin receptor-mediated protection against myocardial ischaemia/reperfusion injury: role of its anti-adrenergic actions. Journal of pineal research, 2008, Volume: 45, Issue:4 Topics: Adrenergic Antagonists; Animals; Colforsin; Cyclic AMP; Guanylate Cyclase; Heart; Indoles; Isoproterenol; Male; Maleimides; Melatonin; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; p38 Mitogen-Activated Protein Kinases; Propranolol; Protein Kinase C; Quinoxalines; Rats; Rats, Wistar; Receptors, Melatonin; Tryptamines	2008
Nitric oxide and downstream second messenger cGMP and cAMP enhance adipogenesis in primary human preadipocytes. Cytotherapy, 2010, Volume: 12, Issue:4 Topics: Adenylyl Cyclase Inhibitors; Adipocytes; Adipogenesis; Adult; Cell Proliferation; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; DDT; Guanylate Cyclase; Humans; Male; Middle Aged; Nitric Oxide; Oxadiazoles; Quinoxalines; Second Messenger Systems; Stem Cells; Subcutaneous Fat; Tissue Engineering	2010
Developmental changes in mesenteric artery reactivity in embryonic and newly hatched chicks. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2011, Volume: 181, Issue:8 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Animals, Newborn; Body Weight; Chick Embryo; Chickens; Colforsin; Embryonic Development; Endothelin-1; Enzyme Inhibitors; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitroprusside; Norepinephrine; Oxadiazoles; Potassium Chloride; Quinoxalines; Vasoconstriction; Vasodilation	2011
Effect of nitric oxide on epithelial ion transports in noncystic fibrosis and cystic fibrosis human proximal and distal airways. American journal of physiology. Lung cellular and molecular physiology, 2012, Oct-01, Volume: 303, Issue:7 Topics: Adenosine Triphosphate; Adult; Aged; Amiloride; Bronchi; Chloride Channels; Colforsin; Cyclic GMP; Cyclic N-Oxides; Cystic Fibrosis; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Free Radical Scavengers; Guanylate Cyclase; Humans; Imidazoles; Middle Aged; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Purinones; Quinoxalines; Young Adult	2012
Pendrin protein abundance in the kidney is regulated by nitric oxide and cAMP. American journal of physiology. Renal physiology, 2012, Sep-15, Volume: 303, Issue:6 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Anion Transport Proteins; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Inhibitors; Imidazoles; Kidney Tubules, Collecting; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroso Compounds; Oxadiazoles; Quinoxalines; Sulfate Transporters; Triazines	2012
The stimulating effects of nitric oxide on intermediate conductance Ca²⁺-activated K⁺ channels in human dermal fibroblasts through PKG pathways but not the PKA pathways. The Chinese journal of physiology, 2014, Jun-30, Volume: 57, Issue:3 Topics: 4-Aminopyridine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dermis; Enzyme Inhibitors; Fibroblasts; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Nitric Oxide; Oxadiazoles; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Quinoxalines; Signal Transduction; Toxins, Biological; Wound Healing	2014
A role for the sodium pump in H2O2-induced vasorelaxation in porcine isolated coronary arteries. Pharmacological research, 2014, Volume: 90 Topics: Animals; Bradykinin; Carbenoxolone; Catalase; Colforsin; Coronary Vessels; Female; Hydrogen Peroxide; In Vitro Techniques; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; Ouabain; Oxadiazoles; Peptides; Polyethylene Glycols; Quinoxalines; Sodium-Potassium-Exchanging ATPase; Swine; Vasoconstrictor Agents; Vasodilation; Verapamil	2014
Inhibition of PDE2A, but not PDE9A, modulates presynaptic short-term plasticity measured by paired-pulse facilitation in the CA1 region of the hippocampus. Synapse (New York, N.Y.), 2015, Volume: 69, Issue:10 Topics: Adenosine; Animals; CA1 Region, Hippocampal; Cadmium Chloride; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Long-Term Potentiation; Male; Morpholines; Neurons; Oxadiazoles; Presynaptic Terminals; Pyrimidines; Quinoxalines; Rats; Rats, Wistar	2015