19-norprogesterone and 19-nordeoxycorticosterone

19-norprogesterone has been researched along with 19-nordeoxycorticosterone* in 1 studies

Other Studies

1 other study(ies) available for 19-norprogesterone and 19-nordeoxycorticosterone

Article	Year
The blood pressure and metabolic effects of 19-nor-deoxycorticosterone and 19-nor-progesterone in sheep. Clinical and experimental hypertension. Part A, Theory and practice, 1984, Volume: 6, Issue:9 The present study examines the blood pressure and metabolic effects of 5 day infusions of 19-nor-deoxycorticosterone (19-nor-DOC) and 19- nor-progesterone (19-nor-PROG) in the intact conscious sheep. Both these steroids raise blood pressure in the rat. 19-nor-DOC (5 mg/d) produced a significant increase in mean arterial pressure (MAP) of 17 mmHg on day 5 (p less than 0.001), associated with 'mineralocorticoid' effects hypokalaemia, hypernatraemia and an initial urinary sodium retention. In contrast 19-nor-PROG (5 mg/d and 50 mg/d) had no effect on MAP and displayed no 'mineralocorticoid' activity. Topics: Animals; Blood Pressure; Desoxycorticosterone; Dose-Response Relationship, Drug; Energy Metabolism; Female; Norpregnenes; Norprogesterones; Potassium; Sheep; Sodium; Water-Electrolyte Balance	1984

Article

Year

The blood pressure and metabolic effects of 19-nor-deoxycorticosterone and 19-nor-progesterone in sheep.

Clinical and experimental hypertension. Part A, Theory and practice, 1984, Volume: 6, Issue:9

The present study examines the blood pressure and metabolic effects of 5 day infusions of 19-nor-deoxycorticosterone (19-nor-DOC) and 19- nor-progesterone (19-nor-PROG) in the intact conscious sheep. Both these steroids raise blood pressure in the rat. 19-nor-DOC (5 mg/d) produced a significant increase in mean arterial pressure (MAP) of 17 mmHg on day 5 (p less than 0.001), associated with 'mineralocorticoid' effects hypokalaemia, hypernatraemia and an initial urinary sodium retention. In contrast 19-nor-PROG (5 mg/d and 50 mg/d) had no effect on MAP and displayed no 'mineralocorticoid' activity.

Topics: Animals; Blood Pressure; Desoxycorticosterone; Dose-Response Relationship, Drug; Energy Metabolism; Female; Norpregnenes; Norprogesterones; Potassium; Sheep; Sodium; Water-Electrolyte Balance

1984